Tennis is a physically demanding sport that requires quick movements, rapid changes of direction, and powerful strokes. Core stabilization is essential for maintaining good posture, generating force, and reducing injury risk. This interventional study aimed to investigate the effectiveness of core stabilization exercises on lumbopelvic rhythm, speed, and agility in adolescent tennis players. Thus, the aim of this study was to assess the impact of core stabilization exercises on lumbopelvic rhythm, speed, and agility in adolescent tennis players. 45 participants (Age 15.66 year’s ± 1.14 years) of both genders: 31 male (height 154.23± 6.67CM weight 48.30±6.36kg) (B.M.I 20.04±1.39) and 14 female (height 15.79±1.05 CM weight 49.29±5.41Kg) (B.M.I 20.54±1.67) with 6 months to 2 years of tennis experience were included in this interventional study. Participant’s pre and post data were collected for lumbopelvic rhythm (Schobers test), speed (30 m sprint test) and agility (T- test). The study results showed significant improvements in lumbopelvic rhythm, speed, and agility among the participants following the core stabilization exercise program. These training programs can enhance athletic performance and reduce injury risk.

The neuropsychiatric conditions; depression and anxiety develop from oxidative stress together with neuroinflammation. The research evaluates if lutein ameliorates anxiety and depression symptoms in rats exposed to scopolamine. 36 male Wistar rats (105g - 153g) were distributed randomly into six distinct groups. Group 1: Negative Control, Group 2: Scopolamine only treated group, Group 3: Scopolamine + Lutein (20mg/kg), Group 4: Scopolamine + Lutein (40mg/kg), Group 5: Scopolamine + Lutein (60mg/kg), Group 6: Scopolamine + Imipramine (standard drug - 10mg/kg). Scopolamine was administered intraperitoneally and lutein orally. Statistical analysis was conducted through one way ANOVA with Post hoc Fischer’s LSD. The experiment used P<0.05 for multiple comparison significance detection. Superoxide Dismutase (SOD), and Glutathione (GSH) levels in Group 2 decreased substantially (p < 0.01 and p < 0.0001) when compared to control, Groups 4, 5, 6 which improved the SOD and GSH levels toward normal levels. Catalase decreased dramatically (p < 0.0001) in Group 2 but treatment in Groups 4 and 5 elevated significantly (p < 0.01). These outcomes establish that Lutein protects against scopolamine induced oxidative stress, behavioral deficits and neurotoxicity. The research established that lutein treatment produced positive results for reversing both oxidative stress conditions and neurotoxicity effects and behavioral deficits provoked by scopolamine. Scopolamine caused a decrease in antioxidant enzymes levels which Lutein treatment at middle and high doses (40 and 60 mg/kg) successfully countered by restoring biomarkers, boosting neurotrophic signals for better behavioral results.

Introduction: Cardiovascular risk factors (RDFs) are on the rise in developing countries, particularly in sub-Saharan Africa. Dyslipidemia, which is often found, can be linked to changes in eating habits. Material and Methods: We performed a prospective descriptive and analytical study to evaluate cardiovascular RDFs in patients who presented with dyslipidemia in general practice. Results: In the 58 patients included, the mean age was 54.15 years ± 13.85 years. The female sex was predominant with a sex ratio (M/F) of 0.41. High blood pressure was found in 68.96% of cases, diabetes mellitus in 32.75% of cases. The mean body mass index (BMI) was 27.65 kg/m2 with extremes of 17.57 and 49.99 kg/m2. The mean waist circumference was 95.94 cm with extremes of 62 and 170 cm. According to NCEP ATP III, 28 women had a waist circumference ≥ 88 cm or 48.27% and 3 men had a waist circumference ≥ 102 cm or 5.17%. The lipid abnormalities were distributed as follows: LDL cholesterol > 1.6 g/l (93.10%), HDL-cholesterol < 0.4 g/l (24.13%), total cholesterol > 2 g/l (96.55%), triglycerides > 1.5 g/l (32.14%). The most common electrical abnormalities on ECG were subepicardial ischemia (8.62%), right bundle branch block (5.17%) and left ventricular hypertrophy (5.17%). The overall cardiovascular risk was elevated in 30.62% of patients. Metabolic syndrome was reported in 82.75% of cases. Conclusion: Dyslipidemia may be the bedrock of latent elevated cardiovascular risk, especially if it is associated with other factors. Prevention involves screening and good awareness by the general practitioner.

Detergents are amphiphilic compounds with crucial roles in the extraction, purification and stabilization of integral membrane proteins and in experimental studies of their structure and function. One technique that is highly dependent on detergents for solubilization of membrane proteins is solution-state nuclear magnetic resonance (NMR) spectroscopy, where detergent micelles often serve as the best membrane mimetic for achieving particle sizes that tumble fast enough to produce high-resolution/high-sensitivity spectra. The best quality NMR spectra use detergents with partial or complete deuteration, which eliminate interfering proton signals from the detergent itself and eliminate potential proton relaxation pathways and strong dipole-dipole interactions that contribute line broadening effects. Another technique for which deuterated detergents have been crucial to obtain structural information about membrane proteins in solution is small-angle neutron scattering (SANS). Use of a deuterated detergent exploits the intrinsic neutron scattering length difference between hydrogen and deuterium, such that detergent is matched-out in D2O and only signal from the membrane protein remains visible in the scattering profile, simplifying data analysis. We provide an updated review on the properties, chemical synthesis and applications of detergents that are commercially available and/or that have been synthesized with partial or complete deuteration, and that have been used in NMR or SANS studies on membrane proteins. Specifically, the detergents are sodium dodecyl sulphate (SDS), lauryldimethylamine-oxide (LDAO), n-octyl-β-D-glucoside (β-OG), n-dodecyl-β-D-maltoside (DDM) and fos-cholines including dodecylphosphocholine (DPC). We also consider effects of deuteration, detergent screening and guidelines for detergent selection.

A series of novel substituted 2-((3-chloro-2-methylphenyl) ((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)amino) benzoic acid (5a-l) derivatives were synthesized using a multi-step synthetic route involving the click chemistry approach. The structures of the synthesized compounds were confirmed using various spectroscopic techniques, including NMR, IR, Mass and elemental analysis. The antibacterial and antifungal activities of the synthesized compounds were evaluated against a panel of bacterial strains (including B. Subtilis, B. Sphaericus, and S. Aureus, P. Aeruginosa, K. Aerogenes and C. violaceum) and fungal species (such as C. albicans, A. Fumigatus, T. Rubrum and T. mentagrophytes). The results revealed significant inhibitory effects, with some derivatives showing superior activity compared to standard drugs. Additionally, the cytotoxicity of these compounds was assessed against human cancer cell lines (MCF-7, PC-3, and HeLa) using MTT assays. Several derivatives exhibited potent cytotoxic effects, indicating their potential as anticancer agents. Molecular docking studies of newly synthesized derivatives 5a-l, along with Doxorubicin and Tamoxifen, against enoyl reductase (PDB ID: 1QSG) indicate potential inhibitors for lipid biosynthesis in cancer therapy.

Wearable cardiovascular devices have emerged as essential tools for continuous heart rate monitoring. Especially for the early detection and management of heart related conditions. This article explores the advancements and functionalities of four categories of the wearable heart monitoring products like, smart patches, in – ear heart monitoring devices, smartwatches and smart rings. The smart patches offer clinical grade heart rhythm data with mobility, allowing real- time analysis without hospital equipment. In- ear monitors, utilizing photoplethysmography (PPG) sensors, provide accurate readings from the ear canal due to its rich blood supply. Smartwatches combine multi sensor capabilities, including heart rate, blood oxygen levels, and ECG, with smartphone integration for user friendly health tracking. Smart rings, the most discreet among them, prioritize minimalism while offering essential metrics like heart rate variability (HRV), sleep, and activity data. These technologies collectively push the boundaries of personalized healthcare, providing accessible, real time cardiovascular monitoring.

Fifteen coal samples were collected from Dangote, Zouma. and Omelewu coal sites, Kogi, State. Five samples from each site were subjected to laboratory tests which include proximate analysis, ultimate analysis, calorific value and total Sulphur content determination to determine their suitability for power generation. ASTM D3173, ASTM D5142, ASTM D3175, and ASTM D5865 standards were used respectively. Tests were carried out at FUTA laboratories and Sheda Science and Technology laboratory, Abuja, Nigeria. Dangote coal is a sub-bituminous B, low Sulphur and medium ash coal; Zouma sub-bituminous C, low Sulphur, medium ash coal, while Omelewu coal is a sub-bituminous C, low Sulphur, low ash coal. The coal samples analyzed are suitable for power generation (Heating value: 8,300 - 9,500 Btu/lb; Moisture content: 16.52% - 17.49%; Low Sulphur content <1.0); low to medium Ash contents 8.0-15.0%) and is in agreement with requirements published by coal-fired power plant operators. Gross calorific values, inherent moisture and contents of Zouma sub-bituminous coal make it more largely suitable for pulverized coal combustion when compared with the coal fuel used for the Genessee Phase 3 power station in Canada.

This narrative review comprehensively evaluates the clinical applications and effectiveness of oral irrigators (water flossers) compared to traditional interdental aids in the management of periodontal and peri-implant diseases. Drawing from an extensive literature search across databases including PubMed, Embase, MEDLINE, and Google Scholar (1971–2025), the review covers historical evolution, current usage patterns, device classification, and future technological advancements in water flossing. Oral irrigators, which utilize pulsating and pressurized water streams, have demonstrated efficacy in plaque removal, reduction of gingival inflammation, and improved access to subgingival and interproximal areas—particularly beneficial for patients with implants, orthodontic appliances, or compromised manual dexterity. Clinical evidence indicates that water flossers are often superior or at least equivalent to dental floss and interdental brushes in reducing bleeding on probing, plaque indices, and inflammatory markers. Furthermore, their synergistic use with antimicrobial agents such as chlorhexidine enhances their therapeutic impact. While water flossers show promise in improving patient compliance and oral hygiene outcomes, certain limitations—such as the risk of transient bacteremia and microbial colonization—warrant further investigation. Innovations like app-controlled devices, biofeedback mechanisms, and AI-driven water flow adjustments represent the future of personalized oral hygiene. Overall, water flossers emerge as effective, patient-friendly tools with broad utility in modern dental care. Continued research and innovation will further solidify their role in promoting periodontal and peri-implant health.

Introduction: Prosthetic joint infection (PJI) is a serious complication of arthroplasty, associated with significant morbidity and therapeutic challenges, particularly due to biofilm formation and the emergence of multidrug-resistant (MDR) bacteria. In Morocco, where osteoarticular trauma and resistant nosocomial pathogens are frequent, a local assessment of PJIs is warranted. The objectives of our study are to determine the frequency of infections in prostheses, specify the epidemiology and resistance profile of isolated strains to antibiotics. Methods: This is a retrospective study conducted in the bacteriology laboratory of the Mohammed V Military Teaching Hospital in Rabat over a 4-year period (2015–2018), involving 572 arthroplasties. Samples were processed using standard microbiological techniques, and antimicrobial susceptibility testing was performed by the disk diffusion method and interpreted according to CA-SFM/EUCAST guidelines. Results: Out of 53 samples received, 37 (69.8%) were culture-positive. Twenty-four cases of PJIs were confirmed, representing an infection rate of 4.19%, predominantly affecting hip prostheses (3.49%). Delayed infections (3–24 months post-surgery) were the most frequent (87.5%). Gram-positive cocci accounted for 59.5% of isolates, followed by Enterobacterales at 31.7%. Staphylococcus aureus was 100% methicillin-susceptible, while 26% of coagulase-negative staphylococci were methicillin-resistant. Resistance rates among Enterobacterales were 32% for cefotaxime and 4% for imipenem. Conclusion: PJIs represent a major issue in our setting, with a predominance of staphylococci and an alarming emergence of multidrug-resistant Gram-negative bacilli. These findings highlight the need for rigorous diagnostic protocols, strengthened preventive measures, and antibiotic policies tailored to the local microbiological ecology.

Prosthetic joint infection caused by Mycobacterium tuberculosis is extremely rare. It can mimic aseptic loosening or chronic infection with common bacteria, delaying diagnosis. We report a case of tuberculous infection in a total hip arthroplasty in a 55-year-old immunocompetent patient, revealed by prosthetic loosening. The diagnosis was confirmed by histology, culture, and molecular biology (GeneXpert). This case highlights the need to consider tuberculosis in the differential diagnosis of chronic prosthetic infections, particularly in endemic areas.

Background: Healthcare workers face high levels of stress, long hours and demanding workloads, which can impair sleep, mental health and job performance. Aerobic exercise has been shown to improve these outcomes by enhancing mood, reducing stress and promoting better sleep. Exploring the effects of aerobic exercise on sleep quality, mental health, and job performance among healthcare professionals is necessary. Aim of the Study: To determine the effects of aerobic exercises on job performance, mental health and sleep quality among interns in Federal Medical Centre, Owo. Material and Methods: This pretest-protest study design involved 40 physically fit healthcare interns at Federal Medical Centre, Owo selected through consecutive sampling. Participants engaged in supervised aerobic exercise sessions; three times weekly for six week, each lasting 40 minutes. Pre and post intervention data were collected using the Werwick-Edinbugh Mental well-being Scale (WEMWBS), Pittsburgh sleep quality index (PSQI), and the Minnesota Job Satisfaction Questionnaire (MJSQ). Data were analyzed using Statistical Package for Social Sciences (SPSS) version 26 with Wilcoxon signed-rank test applied to assess pre-and post- intervention differences at a 0.05 significance level. Results: A total of 37 interns (mean age= 25.54 ± 2.40 years) completed this study. Pre and post intervention comparison of results showed no significant difference in mental well-being (p=0.219) and job satisfaction (p=0.158). However, a significant difference was observed in sleep quality of participants (p=0.001), indicating better sleep quality. Conclusion: Aerobic exercise significantly improved sleep quality, with positive trends (though not significant) in mental well-being and job satisfaction.

Bartholinitis is a common infection of the vulvar region, often polymicrobial in origin. While Escherichia coli and sexually transmitted pathogens are usually implicated, Haemophilus influenzae is rarely identified. We report a case of bartholinitis caused by H. influenzae in a young woman with no notable medical history. This case highlights the need to consider unusual pathogens in bartholinitis and the importance of an appropriate protocol for sample collection and culture.

Background: Female sexual health is often underexplored in the context of chronic liver diseases, despite its key role in overall quality of life. Sexual dysfunction in this population is rarely addressed during hepatology consultations, even though it may be aggravated by clinical complications such as cirrhosis. Methods: This was a cross-sectional, descriptive, and analytical study conducted between January and December 2024, including 106 female patients (53 with chronic liver disease, 53 controls). All completed the FSFI questionnaire. A score < 26 indicated sexual dysfunction. Data were analyzed using Jamovi version 2.2.5. Results: Sexual dysfunction (FSFI score < 26) was observed in 60.4% of patients with chronic liver disease, versus 28.3% in the control group (p < 0.001). The most affected domains were lubrication (84.4%), satisfaction (75%), and desire (65.6%). Cirrhosis was significantly associated with dysfunction (OR = 6.8; p = 0.046). Conclusion: Sexual dysfunction is frequent in women with chronic liver disease, especially in those with cirrhosis. Despite its high prevalence, it remains neglected in routine hepatology practice, underscoring the need for integrated sexual health assessment.

Background: The integration of allied health roles is crucial for enhancing the efficiency and effectiveness of healthcare delivery. Objectives: This review examines the roles of radiology, laboratory services, pharmacy, dental health, and medical secretaries in the context of a multidisciplinary healthcare team. Findings: By analyzing the contributions of these allied health professionals, we highlight the importance of collaboration in improving patient outcomes, streamlining processes, and fostering a holistic approach to healthcare. The review also addresses the challenges faced in integrating these roles and offers recommendations for future practice. Ultimately, the successful integration of allied health roles can lead to improved patient satisfaction, reduced healthcare costs, and better health outcomes. This review underscores the necessity of a cohesive healthcare framework that values the contributions of all allied health professionals, ensuring that patients receive comprehensive and coordinated care. The integration of allied health roles is essential for delivering comprehensive and effective healthcare. By examining the contributions of radiology, laboratory services, pharmacy, dental health, and medical secretaries, we can appreciate the importance of collaboration in improving patient outcomes. Addressing the challenges faced in integrating these roles and fostering a culture of teamwork will be crucial for the future of healthcare delivery. As the healthcare landscape continues to evolve, the integration of allied health professionals will play a vital role in enhancing the quality of care and ensuring positive health outcomes for patients. In conclusion, the successful integration of allied health roles not only improves patient care but also enhances the overall efficiency of the healthcare system. By fostering collaboration, embracing technological advancements, and prioritizing interprofessional education, we can create a healthcare environment that is responsive to the needs of patients and equipped to meet the challenges of the future. The ongoing commitment to integrating allied health roles will ultimately lead to a more effective and patient-centered healthcare system.

Species of Corynebacterium are Gram-positive bacilli, often considered contaminants, but some non-diphtheritic species are now recognized as opportunistic pathogens. We report a case of infective endocarditis caused by Corynebacterium argentoratense, an extremely rare species, in a 59-year-old patient with a history of severe pneumonia. This case highlights the potential emergence of this species in severe human infections and the importance of cautious interpretation of positive blood cultures involving corynebacteria.