CASE REPORT | Jan. 30, 2018
Full Thoracoscopic Resection of Mediastinal Bronchogenic Cyst in Adult
Traibi Akram, Atoini Fouad, Khalil Mounir, Hachimi My Ahmed
Page no 17-19 |
10.36348/sjm.2018.v03i01.003
Bronchogenic cysts (BC) are rare tumours in the mediastinum, but well known to thoracic surgeon. We report a case of symptomatic mediastinal bronchogenic cyst (MBC) in adult who operated on by full thoracoscopy, and we discuss a surgical technic.
ORGINAL RESEARCH ARTICLE | Jan. 30, 2018
A Comparative Study of Erythrocyte Sedimentation Rate by Automated ESR Analyser and Manual Westergren’s Method
Dr. Siva Ranjan D, Dr. Mohammed Abdul Wahab
Page no 44-46 |
10.21276/sjpm.2018.3.1.8
The erythrocyte sedimentation rate (ESR) is a nonspecific screening test to
assess elevations of acute phase proteins that occur in various acute and chronic
diseases. The aim of the study was to compare the ESR values by automated analyzer
against the standard Westergren’s method. The comparison was done among 450
patient’s samples. In which 90 samples showed high degree of difference because of
high ESR values and 180 samples showed low degree of difference because of low
ESR values. The conclusion was automated ESR estimation helped a lot in
measurement of ESR values in short time, but marked difference of ESR values
shown in high ESR values.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
The Lipidemic and Antioxidant Role of Moringa oleifera Leave Extract Following Salt Loading
Archibong AN, Nku CO, Akwari AA, Esiere KS, Ime AU
Page no 6-16 |
10.36348/sjm.2018.v03i01.002
Salt consumption is essential but has a negative health impact when taken in excess. Therefore, this research is aimed at investigating the possible role of Moringa oleifera leave extract on lipids and antioxidant enzymes following salt loading. 24 male albino Wistar rats weighing between 180-240g were used for this study and were divided into four groups (n=6). They were given either normal rat feed and drinking water, high salt diet (8% NaCl diet) + 1% NaCl drinking water and/or Moringa oleifera extract (600 mg/kg b.w., orally, once daily). After six weeks of feeding, the animals were sacrificed and blood collected through standard method for analysis. The salt fed untreated rats had significant (p<0.05) increase in Triglycerides (TG) level, Atherogenic indices (P<0.05), Malondialdehyde (MDA), Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) (P<0.01). These parameters were significantly (p<0.05) reduced to near control values following extract treatment. Salt fed untreated rats were also observed to have significant (P<0.05) reduction in High density lipoprotein (HDL), Catalase (CAT) (P<0.01), Glutathione peroxidase (GPx) (P<0.05), Superoxide dismutase (SOD) and Albumin (ALB) (P<0.01), but the reverse was the case following extract treatment. In conclusion, consumption of Moringa oleifera leaf extract ameliorates the adverse effects of salt loading on the atherogenic, antioxidants and other indices thereby preventing possible outcome of cardiovascular disease, atherosclerosis and other related ailment. It is therefore being recommended for further research and possible use in the manufacture of drugs that are necessary in management of cardiac and other related ailments.
REVIEW ARTICLE | Jan. 30, 2018
The Application of Cohesion in the Translation of Political Documents: Take 2017 Government Work Report as an Example
Li Zhang, Cuimei Zhang
Page no 104-107 |
10.21276/sjhss.2018.3.1.16
The government work report is a kind of style with Chinese characters
of language expression. Therefore, when translating it, the translator must first
understand the source language’s expression and analyze the discourse in order to
make effective language conversion. Cohesion is one of the important methods of
discourse analysis. In this paper, the author, taking 2017 government work report
as an example, analyzes the application of discourse cohesion in government work
report, emphasizing the importance of cultivating the ability of intralingual
understanding and the awareness of cohesion in the process of Chinese to English
Translation.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Overweight and Obesity among Mentally Ill Patients
Umakanth M, Gadambanathan T
Page no 124-126 |
10.36348/sjmps.2018.v04i01.016
Obesity is highly prevalent among patients with schizophrenia, depression and bipolar disorder and is more common in persons with these conditions than in the general population. Excess weight is a major risk factor for impaired glucose tolerance, dyslipidemia, and arterial hypertension, and the clustering of obesity with these abnormalities in the metabolic syndrome correlates strongly with increased risk of coronary heart disease and premature death in all ethnic groups and regions of the world. Treatment with atypical, second-generation antipsychotics (SGAs), particularly clozapine, olanzapine, and quetiapine, are known to promote weight gain, may lead to metabolic syndrome. A descriptive, retrospective study was conducted at the mental health clinic in the Teaching Hospital Batticaloa (THB), SriLanka. Two-thirds of the population 29(63.1%) were found to be overweight 21(45.7%) and obese 8(17.4%).However, one-fourth of the population 12(26.1%) were under normal body mass index(BMI). Patients with mental illness, regardless of age or type of antipsychotic medication in use, were found to be at increased risk for many physical disturbances, including weight gain, dyslipidemia, and increased risk for coronary heart disease; and may benefit from clinical evaluation and adequate treatment, as recommended by international protocols.
REVIEW ARTICLE | Jan. 30, 2018
Salivary Tumor Markers- A Review
Dr. Sudhir MVS, Dr. Sridhar Reddy Erugula, Dr. Deepika Veldurthy, Dr. Ayesha Sameera, Dr. Mohammed Aziz-ur-Rahman, Dr. Shahid Imran, Dr. Mohammed Umar Farooq, Dr. Divya Jahagirdar
Page no 1-7 |
10.21276/sjodr.2018.3.1.1
The first tumor marker reported was Bence Jones protein in 1846 by
precipitation of a protein in acidified boiled urine. The measurement of Bence Jones
protein has been a diagnostic test for multiple myeloma. The first modern tumor
marker used to detect cancer was human chorionic gonadotrophin (HCG), a marker
used in pregnancy tests. High level of HCG in the blood may indicate the presence of
a placental malignancy. After pregnancy if the uterus continues to enlarge; then a
high level of HCG in the blood may indicate the presence of a cancer of the placenta
called as Gestational trophoblastic disease. This marker is still used to help in their
diagnosis & to monitor their response to therapy. The first success in developing a
blood test for a common cancer was in 1965, when Carcinoembryonic antigen was
found in the blood of some patients with colon cancer. By the end of 1970s several
other blood tests had been developed for different cancers. Some proteins are
secreted and/or cleaved into the extra cellular milieu and may represent valuable
serum biomarkers for diagnostic purpose. This review is all about the various
salivary tumor markers which help in diagnosis of oral squamous cell carcinoma.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Understanding the Predictor of Zero-Based Budget Adoption in Borno State
Mustapha Ibrahim, Abdulrahman Shettima, Babagana Mustapha, Mohammed Yusuf, Umar Makama
Page no 16-23 |
10.21276/sjbms.2018.3.1.3
This study aims to predict the possibility of adopting zero-based
budgeting (ZBB) system in Borno State. To ensure this, the study considered
viability as predictor variable that was perceived to have contributed to adoption of
ZBB in the state. ZBB has resurfaced as a prominent topic of discourse due to the
economic downturn experienced in Nigeria as well as the failure of the existing
traditional budgeting system to meet the economic objectives of the government.
The focal point of discourse, therefore, dwelt on Borno state because it is adversely
affected as a result of the revenue volatility witnessed in the country as well as the
level of budget implementation with the existing budgeting system in the state
experienced decade of monumental budget indiscipline at all levels of government.
In view of this, Binary logistic regression was employed to examine whether the
predictor variable have significant influence or not on the dependent variable, that
is, the adoption of ZBB. Stratified sampling technique was used to arrive at a sample
size of 103 drawn from the total population of 139. The findings of the study
established that the adoption of ZBB in the state is politically feasible and offers
more appealing opportunities in minimizing costs and prioritizing government‘s
needs while adding value to the operational efficiency in the budgeting system. It is
therefore, pertinent to recommend the establishment of implementation plan that are
consistent with synergistic principle and application of ZBB which ensure aggregate
fiscal discipline and enhanced technical efficiency through transparency and
accountability.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Biochemical studies in ZnO nanoparticle exposed Eudrilus eugeniae
Abbas M, Meeramaideen M, Mohamed Shamsudin
Page no 56-63 |
10.21276/haya.2018.3.1.11
The adult earthworm Eudrilus eugenia are exposed to four sublethal
concentrations such as 0.25gm/Kg, 0.5gm/Kg, 0.75gm/Kg and 1gm/Kg ZnO NPs.
Biochemical and tissue damaging parameters are studied in Gut, Bodywall and Testis
organs of both control and nanoparticles treated groups. The ANOVA results showed
ZnO NPs treated groups results are significantly differed (p<0.05) than control group.
Total Sugars, Total Cholesterol, Total Protein levels are significantly reduced
whereas increased Urea, transaminase (GOT & GPT) and phosphatase (ALP & ACP)
levels found in treated group organs. The results indicated that exposure of ZnO NPs
through soil disturbed the basic biochemical compounds in tissues and their damages
are indicated by increased enzyme levels.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Exploration of Research Opportunities in the Development of Immediate Release Oral Film of Ondansetron Hydrochloride
Khushboo Patel, Mukesh Gohel, Lalji Baldaniya, Vaishali Thakkar, Tejal Gandhi
Page no 1-17 |
10.36348/sjmps.2018.v04i01.001
The purpose of present research work was to fabricate patient friendly, immediate release oral film of ondansetron hydrochloride using hydrophilic excipients. The film was prepared by solvent casting method. Hydroxyethyl cellulose, polyvinyl alcohol and polyvinylpyrrolidone k30 along with different plasticizers (peg 400 and pg) were scrutinized for film formulation. The auxiliary excipients used were sodium saccharin and sodium lauryl sulphate. The final selection was done with hydroxyethyl cellulose as a film former and peg 400 as a plasticizer for the film. The drug loaded films of hydroxyethyl cellulose were evaluated for thickness, uniformity in drug content, folding endurance, disintegration time, in-vitro drug release studies, tensile strength and drug-excipient compatibility studies. Taste masking was done by novel sandwich technology (placing the ondansetron hydrochloride film between two listerine pocket pack films). This approach can be used as platform technology for other formulations also. Optimization of film was done by 32 factorial design taking amount of hydroxyethyl cellulose and sodium lauryl sulphate as independent variables, while disintegration time (dt), % cumulative drug release and folding endurance as response variables. Polynomial equations were derived. The validity of equations was checked by preparing check point batches. Response surface plots were constructed using design expert software. This exercise facilitates bio batch selection. Better predictive ability was achieved, when artificial neural network (ann) was used in place of regression analysis. Batch of3 containing hydroxyethyl cellulose showed disintegration time of 16 sec and 94.35 % drug release in 8 minutes.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
In vitro Antibacterial Activity of Acalyphin Compound Isolated from Leaves of Acalypha indica Against Human Pathogenic Bacteria
Swapna Gurrapu, Estari Mamidala
Page no 1-4 |
10.21276/haya.2018.3.1.1
The aim of the present study was to investigate the antibacterial properties
of Acalypha indica. Number of resistant antibiotics is increasing and antibacterial
activity testing is one of the steps to find treatment of diseases. Acalypha indica is
well known medicinal plant and it is a wild plant. It was used as infection treatment
for generation to treat several diseases such as asthma, and pneumonia.The
susceptibility of five human pathogenic bacterial species to Acalyphin isolated from
the leaves of Acalypha indica plant was screened using the agar well diffusion and
broth micro-dilution assay. The purity of Acalyphin isolated was checked by TLC
and column chromatography and total Acalyphin were quantified. In the present
study, the inhibitory action of the Acalyphin was found to increase with an increase
in concentration against all bacterial strains. The maximum zone of inhibition was
observed at the concentration of 500 µg/ml against all the bacteria. In this study, the
S. aureus and E. coli are the more susceptible than the other selected human
pathogenic bacteria. From the above investigation the experimental Acalypha indica
plant may solve the multidrug resistant bacteria problem and further higher studies is
need for qualitative study for the present investigation.
CASE REPORT | Jan. 30, 2018
Pleomorphic Adenoma of the Upper Lip about a Case
Faiçal Choumi, Mohamed Sina, Mohamed Moumine, Mohamed Nassih
Page no 147-150 |
10.36348/sjmps.2018.v04i01.021
The pleomorphic adenoma is a benign tumor of the salivary glands. It accounts for 45 to 65% of benign salivary gland tumors. It develops most often in the main salivary glands, especially the parotid, but it can also reach the accessory salivary glands, such as those of the palate or rarely the upper lip. We report a case of pleomorphic adenoma of the upper lip. Patient of 32 years, admitted in our formation for a painless tumefaction of the upper lip, evolving since 6 months. The clinical examination showed a subcutaneous nodule of the superior white lip, of firm consistency, mobile relative to the underlying planes, about 1 cm in diameter. Surgical excision was performed under local anesthesia with a cutaneous approach and removal of the tumor without breaking the capsule. Histological examination revealed a pleomorphic adenoma. Currently there has been no recurrence after three years of decline. The pleomorphic adenoma is a benign tumor of the salivary glands, its preferential localization is the parotid gland, rarely in the accessory salivary glands. The labial localization is very rare. It mainly affects young adult males, often asymptomatic, slow-growing, of firm consistency, well circumscribed in most cases and closer to the mucosa in relation to the skin. Our case has the particularity of being subcutaneous, which posed the differential diagnosis with a tumor of cutaneous origin. The positive diagnosis is based on surgical excision with histological examination. The potential for recurrence is very important, the excision must be complete with a margin of safety avoiding the major capsular intrusion factor risk of recurrence, and prolonged surveillance is required for the search for recurrence or malignant transformation
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Isolation and Characterization of Cyanobacteria from Paddy Field Soil
T. Tamil Kumar and H. Syed Jahangir
Page no 10-18 |
10.21276/haya.2018.3.1.3
Six cyanobacterial strains were isolated from pesticide exposed paddy field
soil by enrichment method. The isolate exhibited unicellular and filamentous
character and are designated and identified as JMCTTKC1-Phormidium
pachydermaticum, JMCTTKC3-Oscillatoria chalybea, JMCTTKC4-Oscillatoria
tenuis, JMCTTKC5-Oscillatoria ornata, JMCTTKC6-Chroococcus dispersus and
JMCTTKC7-Phormidium tenue. The effect of 0.05% of lambdacyhalothrin was
analysed on chlorophyll-a and protein content of the cyanobacterial isolates in
mineral medium at different time intervals. The maximum level of chlorophyll-a
content JMCTTKC4-Oscillatoria tenuis-39.3500µg/mL and protein content
JMCTTKC6-Chroococcus dispersus- 99.9µg/mL was recorded on the 9th day sample.
At the same time decreased level of chlorophyll-a content JMCTTKC1-Phormidium
pachydermaticum-3.8597µg/mL and protein content JMCTTKC3-Oscillatoria
chalybea 24.73µg/mL was observed on 13th day sample. From this above observation
it was clearly noted that the selected isolates are capable of degrading
Lamdacyhalothrin pesticide and used its metabolites as a sole carbon and nitrogen
source for their growth.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Distribution of Blood Groups in Donors and Functioning Pattern of a New Semiurban Blood Bank
Monalisa Dhuya
Page no 119-123 |
10.36348/sjmps.2018.v04i01.015
Blood transfusion system is a basic necessity of health care delivery system. As off now more than 700 antigens and about 30 blood group systems have been identified. ABO and Rhesus (Rh) blood group systems are most important tool for blood transfusion, parental testing, legal medicine and in population genetic study. It is immensely important to identify the working pattern of a blood bank of rural West Bengal as it will facilitate to generate appropriate policies for better service. The main objective of the study is to determine age and sex wise frequency and distribution of ABO and Rh blood group pattern among blood donors and working pattern of newly developed blood bank and compare with other data from similar studies. Retrospective study was conducted at Blood bank of Khatra Sub-divisional Hospital, West Bengal over a period of one year. Blood group of the donors was determined by standard monoclonal antisera test by tube agglutination technique. Out of 1802 blood donors, 88.62% were male and 11.38% were female. 63 donors were deferred due to hypertension and diabetes. The commonest blood group observed was O+Ve followed by B+Ve and the rare one was AB-Ve. The study had a significant implication regarding the inventory management of blood bank and transfusion services for the patient admitted in the sub-divisional hospital of rural West Bengal and also necessary for the health planners while making efforts to face the future health challenges in this region
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Moulting of Freshwater Crab Maydelliatelphusa masoniana Reared in the Laboratory Conditions
Kuldeep K. Sharma, Rakesh K. Gupta, Seema Langer
Page no 19-21 |
10.21276/haya.2018.3.1.4
Presently an experiment was conducted so as to understand the moulting
behaviour in freshwater crab Maydelliatelphusa masoniana in the laboratory
conditions. Out of eight crabs only five could moult while three died during ecdysis.
All the crabs exhibited the same pattern of moulting viz., appearance of double lining
in pereiopods, the old carapace becoming light in colour follow by its split along the
posterolateral margin of the dorsal side, anterolateral border of the ventral side and
posterior border of the chelipeds and legs. A new pre-exuvial soft layer is formed
below the old carapace. The whole process of moulting got completed within 20-25
minutes.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
The Impact of School Based Staff Development Programmes in Secondary Schools of Gweru District of Zimbabwe
Dr. Caxton Shonhiwa
Page no 35-40 |
10.21276/sjbms.2018.3.1.5
Staff development is crucial as it equips workers with life long survival
skills on their jobs. Staff development also bridges the gap between the teachers’
available acquired skills and the new teaching skills required in the curriculum.
Staff development is therefore concerned with the expansion of knowledge and
skills of teachers so that they contribute to their growth in relation to their jobs and
improve student learning through enhanced performance by the teachers. This study
sought to evaluate the effectiveness of school based staff development programmes
in Zimbabwean secondary schools using the quantitative paradigm. The study
employed the survey descriptive design. The target population comprised all
schools in Gweru District using a sample of 220 teachers and heads composed of
112 females and 108 males. All the information was collected using a questionnaire
which had both close-ended questions and open-ended questions. The study
revealed that lack of follow up evaluation sessions to staff development programmes
affect the effectiveness of staff development design and implementation. The study
also revealed that time allocated to staff development programmes was not adequate
resources. The study recommends that there should be adequate resources to
effectively plan and implement staff development programmes and that staff
development programmes must be allocated enough time for them to be effectively
carried out.