The aim of the present investigation was to develop controlled release tablet of Abacavir sulphate using. Azadirachta indica (Neem gum) and comparison with official guar gum (BP). Additionally, physiochemical properties of the gum were evaluated. Totally five batches abacavir containing extended release tablets were designed using neem gum / guargum characterized for preliminary trial. Best formulation was selected for optimization by 22 central composite design. In this Input variable were Neem gum/Guargum (X1) and Microcrystalline cellulose (X2). The output variables were Hardness (Y1) friability (Y2) swelling index (Y3) and in vitro release (Y4). The optimized formulations were subjected for inviro-invivo correlation. The study results revealed optimized batch A2 showed hardness of 5.8 kg / cm2, friability 0.63 %, swelling index 84.3% and in vitro release of 90% over the period of 12 h. A higher similarity between optimized tablets and Abamune tablets (Cipla) was established with similarity factors f2 was 50 .7.pH 6. 8 phosphate buffer. Also the in virtro in vivo correlation coefficient obtain from point –point analysis of optimized tablets was 0.98. The optimized tablets exhibit super case 11 mechanism.

The present study investigates the comparison of hand hygienic practices in nurses of neonate and pediatric unit allied hospital and DHQ hospital Faisalabad. Hand hygiene is a primary measure to reduce infection in neonates. Hand hygiene is a simple procedure. That can help in reducing morbidity and mortality rate. The purpose of this study is to comparison of hand hygienic practices in nurses of neonate and pediatric unit Allied hospital and DHQ hospital Faisalabad. To assess nurses compliance of hand hygiene related to new born care. To assess association between hand hygiene training and hand washing practice. The study’s methodology involved descriptive quantitative study design. Sample size was 180. Questionnaires were distributed to the nurses of two hospitals. 150 questionnaires returned back. Questionnaire was containing in 3 sections. The data analysis was done using SPSS software version 21. Results describes about I receive formal training for hand hygiene. Results indicate that 100% respondents were Agree with the statement. The mean is 1.0000 with .00000 standard deviation. Results describes about There is a relationship between good hand hygiene practice and hospital acquired infections. Results indicate that 88.0% respondents were strongly agree, 12.0% agree with the statement. The mean is 1.1200 with .32605 standard deviation. Results describes my clinical nursing instructor consistently performs HH when necessary. Results indicate that 65.3% respondents were strongly agree, 28.0% Agree and the UN decided 6.7% with the statement. Hand washing is a primary measure to reduce infection and prevent spread of health care associated infection. Descriptive quantitative design used for this study. Data was collected through adopted questionnaire Descriptive statistics was used for analyzing date.

The gastroretentive drug delivery system is site-specific and allows the drug to remain in the stomach for a prolonged period of time so that it can be released in a controlled manner in the gastrointestinal tract. The purpose of the research work is to formulate and optimize the gastro retensive film (GRF) containing Propranolol hydrochloride in order to prolong the release time and improve the bioavailability. Five basic gastroretensive films were developed by solvent casting method for preliminary trial . The best formulation was subjected for two factor two level design approach. Independent variables selected were concentrations of Eudragit S 100 (X1) and Eudrajit RL 100 (X2) and dependent variables were Folding Endurance (Y1) Tensile strength (Y2) Elongation at break (Y3) and in vitro drug release (Y4). The results of the study indicate optimized formulation (P2) exhibit folding endurance 114, tensile strength 1.3 kg mm2, Elongation at break 22% and in vitro release 46.5 % for 12h. The in vitro release data were well fit into Higuchi and Korsmeyer-Peppas model and followed non-Fickian diffusion mechanism. The gastro retensive formulations can be used in diseases where an extended release of propranolol is required.

The studywas to evaluate the relationshipbetween performance appraisal system and staff retention in Enugu Electricity Distribution Company of Nigeria. The specific objectives include to; examine the relationship between employee’s rate of output produced and employee training. Examine the relationship between employee recognition and achievement of organizational goals. The population consists of 983 staff of Enugu Electricity Distribution Company of Nigeria (EEDC).The study used the survey approach. The primary sources used were the administration of questionnaire to staff. The 274 sample size of the study, the study used the Freund and Williams’s formula. 261 staff returned the questionnaire and accurately filled. The validity of the instrument was tested using content analysis and the result was good. The reliability was tested using the Pearson correlation coefficient (r). It gave a reliability co-efficient of 0.82 which was also good. The hypotheses were analyzed using f-statistics (ANOVA) tool. The findings indicated that there is positive effect relationship between employee’s rates of output produced and employee training F(95,n= 274)= 827.372,P<0.05;This indicates that there is positive effect relationship between employee recognition and achievement of organizational goals F(95,n=274)= 367.439,P<0.05.The study concluded that appropriate training and development programmes would be designed to correct deficiencies through performance appraisal. The study recommended that Performance appraisal should be encouraged in organizations to assists workers and management meets their expected target and Recognition of employees by the management should be a top issue in organization to enable workers gives out their best.

Laryngeal tuberculosis is an extra pulmonary form of tuberculosis and is found in about 2% of all tuberculosis cases. A retrospective analysis of 31 cases of laryngeal tuberculosis was done in the present study extending for 30 years in three Medical Colleges of West Bengal, India. Out of these 31 cases in the study, 20 patients were male and 11 were female with an M: F Ratio of 1.8:1. The age of the patients ranged from 31 years to 59 years. The highest incidence of 45.2% was observed in the age group of 51 to 60 years, followed by 35.5% in the age group of 41 to 50 years and 19.4% in the age group of 31 to 40 years. All the patients presented with hoarseness of voice and cough was the second common symptom. Out of the 31 patients, 9 patients complained of pain in the throat and seven of those had referred earache also. In majority of the cases, the lesions were limited to the vocal cords, arytenoids, and posterior commissure. False cord was involved in 15 cases and ulcer over the arytenoid was found in 14 cases. Patients with lesions involving only the vocal cords, presented with hoarseness of voice, whereas lesions involving the other areas of the larynx, such as arytenoid and aryepiglottic fold presented with odynophagia. Enlargement of the regional lymph nodes was observed in 5 cases out of the total 31 cases. Most of the cases were found during the first 20 years of the study whereas only 4 cases were found during the last 10 years, which could be attributed to the successful implementation of the Revised National Tuberculosis Control Programme in India. However, the emergence of multi drug resistant strain of the causative bacillus and tuberculosis-HIV co infection has complicated the scenario at present. On histopathological examination, tubercular granuloma with stromal hyperplasia, large number of phagocytes and giant cells, epitheloid cells, Langhans cells and typical necrosis with caseation were found. Confirmation of the diagnosis utilizing a proper diagnostic algorithm and treatment with specific Anti Tubercular Drugs (ATDs) are most important in the management of laryngeal tuberculosis.

Over the past two decades, gulf cities have been rapidly growing, mainly after the discovery of oil. Large-scale urban projects have been constructed as a result of globalization, which has affected the built environment and the urban fabric of gulf cities. Doha, the capital city of the State of Qatar, has been substantially influenced by globalization. The city has experienced great transformation in its environment since the 1950s, after the discovery of oil. Therefore, Doha has faced the challenge of keeping pace with urban developments that have been increasing and taking over the existing heritage embedded in buildings and traditional neighborhoods. Al-Hitmi is one of the neighborhoods affected by urbanization and sprawling. This research study investigates Al-Hitmi neighborhood and its features, opportunities, constraints, and relationship with the surrounding areas, specifically Qatar National Museum and the Museum Metro Station. The research design is based on the review of the literature, site analysis of the selected case, and surrounding context in order to (1) find opportunities and challenges and (2) to propose a strategy for the urban regeneration of the neighborhood of AlHitmi.

Thymomas are among the most common anterior mediastinal tumors that can uncommonly present with respiratory failure. This case – A 62 year old lady who presented with complaints of limb weakness and the development of type II respiratory failure, discusses in detail the problem posed and the workup leading to the diagnosis. Surgery was performed based on the radiological findings. The tumor was completely resected and the diagnosis given as Masoka classification‑Type B2-predominantly cortical thymoma

Over the past three decades, rapid urban sprawl, a changing economy, and shifting demographics have caused rapid developments, which included the urban regeneration of existing neighborhoods. In the 1940s, after oil and natural gas discoveries in the State of Qatar, Doha experienced massive transformations on social, economic, cultural and environmental levels. These transformations have created (A) the need for creating sustainable neighborhoods and (B) raised questions related to how existing neighborhoods can be more sustainable in the future. This study investigates the neighborhood of Msheireb Downtown Doha and the reasons which have caused its urban regeneration. The study investigates (1) practical forms of sustainable urbanism principles by analyzing the Msheireb project and (2) how this urban project can be enhanced according to these principles. The research design encompasses a summary of the literature, the site analysis, structured interviews and a resultant vision of a sustainable concept for Msheireb to define the actions needed to implement the sustainable neighborhood concept. The findings reveal that, comparing the image of old Msheireb with the current regenerated one, the later neighborhood is compact, pedestrian-friendly and mixed use, which in turn encourage people to engage and promote a higher level of social interaction and therefore, contribute to enhancing the urban livability of the neighborhood.

Anacyclus pyrethrum L. root is one among the ingredients of polyherbal formulation frequently employed for the treatment of stress by Ayurvedic practioners. So, the objective of this study was to scientifically validate its use. Animals were administered graded doses of ethanolic extract of Anacyclus pyrethrum root and subjected for anoxia stress tolerance test, swimming endurance test and acetic acid induced writhing test models and its adaptogenic potential was assessed by estimating various parameters. Stressed animals demonstrated altered values of these parameters. Ethanolic extract of Anacyclus pyrethrum root exhibited significant anti-stress activity by restoration of all the altered values. Present findings validate its use in Aurvedic system of medicine.

The purpose of this study was to assess the relevance of vernacular radio stations’ agricultural programs in influencing utilization of agricultural information among farmers in Molo Sub County, Nakuru Kenya. Agricultural sector provides a livelihood for about 80% of Kenya‘s population and employs more than 70% of the rural population hence it remains valuable for the provision of food and employment opportunities. Vernacular radio stations, as part of mass communication, has a wider audience in rural areas compared to other forms of media outlets. Therefore, they have led to the passing of novel information on agriculture to farmers in Molo Sub County, Nakuru Kenya. This study adopted a cross-sectional survey research design whereby 8,445 households in Molo sub-county were targeted. Cluster sampling method was used to determine the number of participants that was selected through systematic sampling. The target population was 155 respondents in Molo Sub County Nakuru Kenya and the response rate was 94.9%. A Questionnaire was used to collect data and pilot testing was done in Subukia Sub County Nakuru, Kenya. Descriptive statistics showed that 83.9% of the respondents listen to the agricultural program while 16.1% disagreed to listening to agricultural activity. The study established that there exists a statistically significant relationship between demographic characteristics, relevance of agricultural programs, institutional factors and utilization of agricultural information (r= 0.644; p<0.05, r= 0.503; p<0.05, r= 0.463; p<0.05) respectively. The study concluded that demographic characteristics had a very high influence in the utilization of agricultural information among farmers in Molo Sub County, Nakuru Kenya. This deduced that radio agricultural programs are useful to farmers in Kenya and have greatly influenced their farming practices. The study recommended that there is a need for more effort in providing agricultural information programmes to farmers.

The spatial patterns of urban land use at both the macro and the micro levels are a central issue in global change studies. The land use/land cover (LU/LC) changes are real important to have proper provision and use of natural resources and their management. Land is becoming a scarce resource due to immense agricultural and demographic pressure. Hence, information on land use /land cover and possibilities for their optimal function is essential for the selection, preparation and implementation of land use schemes meet the increasing needs for basic human needs and welfare It was done by using the data SOI Toposheets, Landsat TM, (1991), Landsat ETM+ (2001), LISS-III (2011) and LISS –IV (2016) and with the aid of using Remote Sensing and Geographical information Techniqnies. The supervised classification method is used to classify the land use and land cover of the study area. The major findings of change detection analysis revealed that the maximum change in the land use and land cover from 1981 to 2016 has been seen in the instance of the built-up area, which has varied from 2.89% to 40.36%. The major expansion of the built-up area is mainly along the highways and the outskirts.

An experiment was conducted at the Regional Agricultural Research Station, Jamalpur, Bangladesh which geographic coordinates located between 24034ʹ and 25026ʹ north latitude and between 89040ʹ and 90012ʹ east longitude during the period from November, 2015 to March, 2016 to observe the growth and yield performances of the rapeseed-mustard varieties under field condition grown from the seeds of different stages of siliquae maturity of the previous year experiment. Four rapeseed-mustard varieties viz. BARI Sarisha-11 (V1), BARI Sarisha-14 (V2), BARI Sarisha-6 (V3) and Tori-7 (V4) and seeds of those varieties harvested at four stages of siliquae maturity viz. H1 = Green stage of siliquae, H2 = Pale yellow stage of siliquae, H3 = Golden yellow stage of siliquae and H4 = Full maturity stage of siliquae were included as the treatments in the experiment. Harvested seeds of the previous year were stored in air tight polythene under freezing condition till set up the experiment. Results revealed that four rapeseed-mustard varieties varied significantly for most of the parameters studied. Variety V1 produced significantly the highest seed yield (1.99 t ha-1) while the lowest (1.04 t ha-1) was recorded from V4. Seeds of H2, H3 and H4 stages produced statistically similar and significantly higher seed yield ranges from 1.57-1.65 t ha-1 (H4>H3>H2)) than that of H1 stage which produced the lowest (1.34 t ha-1) mainly due to the poor stand establishment. Interaction effects of varieties and seeds harvested at different stages of siliquae maturity did not show significant variation in expressions of seed yield and yield contributing parameters.

Access to justice suffers a number of challenges and results to ineffective functioning of the justice system. Despite the existence of empirical studies on strategy implementation and strategic planning in the Judiciary, no research has been carried out on the effect of case management on access to justice. The population of the study comprised one hundred and thirty five respondents being magistrates, Judicial staff, Office of the Director of Public Prosecutions (ODPP) counsels, advocates, police and prison services, children and probation officers based in Molo Law courts. The study used the descriptive research design. Stratified proportional sampling was used to categorize various stakeholders into strata and determine the number of participants that would be selected from each stratum. Simple random sampling was used to select individual respondents from each stratum. Primary data was collected by use of questionnaires, where quantitative data was analyzed using both descriptive and inferential statistics specifically Spearman correlation analysis, while qualitative data was analyzed using thematic analysis. The study targeted to collected data from 94 individual but only 72 were able to complete and return their questionnaires to the researcher. From the study findings, the values of Spearman correlation coefficient were r = 0.735 for case management. This implies that the way case management is handled is an important determinant of whether there will be access to justice or not.

This study’s aim was to establish the relationship between peer pressure and high-risk sexual behavior among high school students in Kenya. Twenty-eight students were sampled per school from form 1 to 4, which summed to 138 students in Nakuru East Sub County. Primary data was gathered from the 138 students through a structured questionnaire. Interviews were conducted to the school head teacher. Only 120 respondents were able to fill in the questionnaires.This meant that the response rate was 87.6%. The focus group discussions were done successfully as well as the interviews scheduled with the head teachers. Quantitative data was analyzed through statistical package for social sciences (SPSS) using cross tabulation and chi-square to determine response frequency and percentage. Cross tabulation was used to analyze the variables using tables and was supported by qualitative data. The Pearson Chi Square was 0.00 indicating that peer pressure influenced high-risk sexual behavior among high school students in Nakuru East Sub County, Kenya. The study found that peer pressure influenced the students’ decisions on sex and relationships. The study concluded that peer pressure was an influence to high-risk sexual behaviour among high school students and the youth in general. It influenced the decisions they made on dating, sexual relationships, and sex. The study recommended that sex education should be included in the curriculum in order to help the students on gaining knowledge on life skills.

This study assessed the influence of outbound logistics on retail marketing at Naivas Supermarket. The purpose of the study was to rate and appraise the success of company’s outbound logistics process by rating the success of transport logistic activity based on the supermarket retail marketing. The objective of the study was to assess how transportation affects outbound logistics of retail marketing at Naivas Supermarket. The study was informed by the organizational theory. The study utilized the descriptive research design. Purposive sampling was used to get a sample of 45 respondents who included the regional managers, branch managers, stock co-coordinators, floor supervisors and shelf stockers out of which 39 completed the study. The study collected both quantitative and qualitative data using both questionnaires and interviews. The research will collect and analyze both qualitative then quantitative data to get results of this research. Quantitative data was analyzed using descriptive statistics mainly frequencies, percentages, and the Pearson chi-square while qualitative data was analyzed using the thematic technique. Findings reveal that Naivas Supermarket generally employs a centralized transportation where the company is directly involved in managing logistic services rather than outsourcing this function to third parties. The analysis of outbound logistics transportation had an effect (mean=8.9667). The chi-square test established that outbound logistics transportation (X2= 12.208, p= 0.043). The study recommends that to improve retail marketing, the supermarket should automate the process of loading and offloading goods before and after transportation.