In the work, modeling of the forming process for aluminum detail was carried out. As a detail, "Pen" is chosen for which the material AK6M2 is determined, taking into account its physico-chemical properties. In the beginning, a 3D detail model is constructed, using the SolidWorks program. Then in the program Nova Flow, entire process of filling the mold in real time, rate of filling the mold cavity with metal, hardening time of the casting was determined. The temperature change dynamics of the casting after filling the mold is investigated. Possible nodes are susceptible to formation of shrinkage shells.

Phytomedicines are becoming more popular in the world for their ability to cure diseases with less toxicity and better therapeutic efficacy. Herbal medicines may also have disadvantages of poor bioavailability, toxicity, stability issues and patient compliance. In order to minimize these problems various drug delivery systems such as liposomes, phytosomes, niosomes, ethosomes and trasferosomes etc are being developed for phytomedicines. Novel drug delivery systems can improve bioavailability of drug that refers to the existence of drugs in the body part where they are actually needed. Ethosomes are noninvasive flexible vesicular carriers that enable the drugs to permeate through the deeper layers of skin and systemic circulation. They are mainly composed of phospholipids, high concentration of ethanol and water. As ethanol is known for its disturbance of skin lipid bilayer arrangement; therefore, inclusion of ethanol into a vesicular membrane provides the ability of vesicle to permeate through the stratum corneum. The high flexibility of ethosomal carrier from the added ethanol allows the elastic carrier to squeeze through the skin pores. Herbal ethosomal formulation has been effectively used to enhance bioavailability of many herbs including Glycyrrhiza glabra, Sophora alopercuroides, Cannabis sativa, Sesbania grandiflora and Podophyllum hexandrum

Medicinal plants are used for their beneficial properties to the health of animals. Recently, it has been found that the use of medicinal plants eliminates industrial pollutants. The objective of our work is to determine and evaluate the effect of two medicinal plants (Thymus algeriensis and Artemisia campestris) on oxidative stress parameters in sheep. The results obtained in liver cells show that medicinal plants have produced a globally antioxidant preventive effect, this is revealed by the significant decrease in the GSH level (199.976±1.913), and the enzymatic activity of CAT (0.699±0.02). In addition, an increase in the enzymatic activities of GST (0.435±0.017), GPx (1.881±0.040) and MDA (29.009±0.086) was observed. These results clearly show an antioxidant effect of medicinal plants on the organism of sheep.

Patients with multiple myeloma may present a variety of renal manifestations as a result of damage from circulating light chain immunoglobulin components. The renal alterations can interest any of the renal compartments, and in certain cases more than one compartment can be affected. The resulting high serum concentrations of these proteins often lead to tubular interstitial injuries as endocytic receptors in the proximal tubules are overwhelmed. A 46-year-old white man with a history of left hip pain was diagnosed as multiple myeloma. Imaging including MRI and PET scan showed a left pelvic heterogenous mass causing bone destruction and compressing the adjacent organs. He was referred to the nephrology department due to the onset of acute kidney injury requiring hemodialysis. A kidney biopsy was performed and showed patterns of acute interstitial nephritis and focal linear staining for kappa light chains along tubular basement membranes on immunofluorescence. After glucocorticoids for acute interstitial nephritis and chemotherapy (Bortezomib -Cyclophosphamide - Dexamethasone) directed against the clone, the renal function partially improved and the patient got off hemodialysis support. Conclusion: Acute kidney injury may be the first clinical presentation in patients with multiple myeloma. Could interstitial nephritis be the only manifestation of MM without myeloma cast nephropathy and whether it was glucocorticoid or chemotherapy directed against the clone that has resulted in a significant improvement in renal function.

Bacopa monnieri or Brahmi(family- Scrophulariaceae) used in indigenous medicine as nerve tonic and cardio tonic possess diuretic, adaptogenic, antioxidant, antidepressant, antibacterial properties, enhances cognition profoundly flourishes in the marshy regions. Preliminary phytochemical tests carried out using aqueous, ethanol and methanol extracts revealed the presence of phytochemicals like amino acids, alkaloids, carbohydrates, glycosides, flavonoids, phenol, saponins and tannin accounted for its medicinal aspects in organic solvents.

SMEs are recognized as a most effective mechanism to push economic and social development. Their role becomes more important in Saudi economy which is in the diversification stage in an attempt to reduce KSA dependence on oil and to realize the Vision 2030. The government has established various institutions and working along with private sector to offer SMEs financial, technical and training support aimed at development of entrepreneurship. In this paper an attempt has been made to examine the status of SMEs and to identify & study the activities of the institutions extending financial and non-financial support to SMEs. The researcher has examined thirteen main institutions which are playing an important role in providing support in the areas of technology, marketing, financing, training, incubators, consultancy and policy & incentives. Finally suggestions have been extended for further improvement in order to capitalize the opportunities resulting in development and growth of entrepreneurship.

Ipomoea sepiaria Roxb., also known as Purple heart glory is a slender vine belonging to family Convolvulaceae. In Sanskrit it is known as lakshmana, in hindi as Bankalmi and in Malayalam as Tirutali. It is one among the ten sacred plants known collectively as “Dasapushpam” in Kerala. These plants are used for rejuvenating the body in the form of „karkidakakanji‟ in the monsoon season in Kerala which is also prescribed in text books of ayurveda. Juice of the plant is used as deobstruent, diuretic, hypotensive, uterine tonic and antidote to arsenic poisoning. The present study aims at the preliminary phytochemical screening of the successive solvent extracts of Ipomoea sepiaria Roxb. and identification of compounds in the Hexane extract by Gas Chromatography- Mass Spectrometry technique. The preliminary phytochemical screening revealed the presence flavanoids, tannins, flavanoids, terpenoids, steroids, sterols, cardiac glycosides and carbohydrates. The GC-MS analysis revealed the presence of the compounds Caryophyllene, α –Curcumene, β – Cadinene, ϒ –Elemene, Caryophyllene oxide, Asarone, Germacrone, Methyl isopimarate, Abietic acid, Lupeol, β –Amyrin and α –Amyrin which have not been so far reported in Ipomoea sepiaria. The higher percentages of compounds α- amyrin(33.341) β –Amyrin(16.28) which form the basic skeleton of triterpenoid saponins are promising.

Iron deficiency anemia is widely prevalent nutritional disorder worldwide, resulting in oxidative stress which in turn leads to cardiovascular diseases, cancer, diabetes mellitus and ageing. Oxidative stress and iron levels were studied in 84 subjects, 36 of whom were anemic (Hb <11 gm/dl) and 48 healthy subjects who were taken as controls. In these subjects serum iron, Total Antioxidant Capacity, superoxide dismutase and malondialdehyde levels were estimated. In the present study it was found that anemic subjects had higher oxidative stress as compared to controls and female anemia subjects were more affected than males. Preventive action may help in reducing the morbidities caused by the oxidative stress

Seeds of Myrianthus arboreus P. Beauv were collected from from Didoko forest, at 140 km from Abidjan (Côte d‟Ivoire). One part of seeds (about 1 kg) was dried at sun (30-35°C) for a week (Dried Seeds, DS). A second part (1 kg), was boiled in water (100°C) for 30min (Boiled Seeds, BS). Oils were extracted using chloroform and methanol as solvent and the content in oil was determined by gravimetry. Physicochemical caractéristiques were determined using the méthodes of the American Oil Chemists Society. The total lipid contents of myrianthus arboreus seeds were 45.82±2.16 and 46.02±0.49; respectively for DS and BS. Physicochemical properties of these oils showed that acid values ; saponification and peroxide values and the iodine indices were 1,94±0.1 and 3,00±0.17 mg KOH/g ; 136,68 ± 0.32 mg KOH/g of oil and 148,36± 0.64 mg KOH/g of oil ; 5,49± 0.49 mEq/Kg and 5,6±0.10 mEq/Kg ; and 104,037±0.037 g I2/100g and 103.O42±0.042 g I2/100g respectively for DSO and BSO. The colours of myrianthus arboreus seeds oils were yelloworange for DSO and pale yellow for BSO respectively. The quality and stability of traditionally processed myrianthus arboreus seeds oil as affected by temperature were evaluated by analyzing their physicochemical properties which included acid, saponification, peroxide, and iodine indices.

This study was carried out to investigate the prevalence profile of cutaneous adverse drug reactions (CADRs) on in patients at Tongji hospital. A retrospective study was carried out on in-patients at Tongji medical college, Huazhong university of Science and Technology from May 1985 to April 2012. Out of 110553 in-patients 777 cases were diagnosed as CADRs. The most common type of CADRs was maculopapular eruption followed by Erythema multiforme, Fixed drug eruption and urticaria. The most common drugs causing CADRs was antibiotics followed by antiepileptic drugs, antipyretics and analgesics. The most common type of CADRs was maculopapular eruptions followed by erythema multiforme, fixed drug eruption and urticaria. The main offending drug was antibiotics followed by antiepileptic drugs, antipyretics and analgesics

Crop simulation models are used in predicting crop productivity under various crop management options and changing climatic parameters that require determination of genetic coefficient of a crop cultivar. Successful use of a crop model depends on the accuracy of calibration and validation of different parameters. This paper aimed to evaluate the DSSAT (v4.6) crop model in Bangladesh for wheat production. Genetic co-efficient of four wheat cultivars (BARI Gom-25, 26, 27 & 28) were determined through DSSAT model. Experimental data on irrigation and nitrogen effect on wheat production was used for model calibration and date of sowing effect for model validation. Model evaluation results showed closer estimation of crop growth duration, grain and biomass yields. Percent error difference in grain yield of wheat varieties (BARI Gom- 25, 26, 27 and 28) between simulated and observed values were 10.98%, 8.70%, 10.79% and 8.94%, respectively. Relationship between simulated and observed grain yields, and simulated and observed crop duration both at calibration and validation process are strong having higher R2 value. The model has been successfully calibrated and validated for wheat growing in Bangladesh environment and can now it can be taken for further applications in natural resources management and climate change impact studies.

The management of the cervical lymph nodes is an integral part of the overall treatment of the oral cavity malignancies. The indications and uses of the various types of neck dissections and pre and postoperative radiotherapy has been a subject of much debate. Based on the results of the present study and the literature available with us, we can conclude that, Dissemination of metastatic cancer to regional lymph nodes from primary sites in the upper aerodigestive tract occurs in a predictable and sequential pattern. For primary tumours in the oral cavity, the regional lymph nodes at the highest risk for early dissemination by metastatic cancer (first echelon nodes) are limited to levels 1,2 and 3, i.e., within the supraomohyoid triangle of neck. Skip metastasis to levels 4 and 5 in the absence of metastasis at levels 1,2 or 3 is very rare.

The purpose of the present work was to evaluate the proximate composition, minerals content (Na, K, Ca, Fe, Mg, Cu, Zn, Mn), simultaneous quantification of water soluble vitamins (like ascorbic acid, thiamine, riboflavin, niacin, pantothenic acid, pyridoxine & folic acid) by HPLC of three different grasses viz. Cynodon dactylon, Apluda mutica and Eleusin indica. The result showed the highest calorific value of C. dactylon (124.031 ± 1.154 kcal/100g) which was also found to contain highest amount of protein and carbohydrate. An appreciable quantity of carbohydrate was estimated in the aerial parts of E. indica (17.762 ± 0.122%). E. indica had the highest potassium content (2.207 ± 0.006 mg/g) and calcium content (6.023 ± 0.002 mg/g). The sodium content ranged between 0.049 – 0.289 mg/g. The aerial parts of E. indica (274.945 ± 0.085 mg/100g) contained a very good amount of vitamin C. The water soluble B vitamin content in these plants under investigation ranged between 0.009 to 12.133 mg/100gm. In conclusion, the results indicate that these IAS can be utilized as food supplement.

Breast feeding with timely started complementary feeding is the best way of infant feeding. It is necessary for infant’s overall development, better growth, fulfilling nutritional requirement and it is most vital for reducing infant mortality. Objective of our study was to assess the knowledge, attitude and practice of complementary feeding among mothers in a tertiary Care Centre of Central India. A cross sectional study was done about knowledge of mothers with children below 2 year of age with help of pretested self-designed questionnaire based interview who are attending paediatrics OPD and IPD. In our study most of mothers did not know correct time of starting complementary feeding, they also did not know what food can be given, frequency and amount of complementary feed. In our study knowledge, attitude as well as practise towards complementary feeding was lacking hence health education to mother and family members required about correct feeding in early years of life.

The impact of culture environment was assessed for the production of GIFT tilapia over high stocking densities at 20 fish/m2 and 30 fish/m2 in ponds and 300 fish/ m3 and 400 fish /m3 in cages in the same ponds to ensuring maximum utilization of the pond resources. After 120 days culture period the highest net yield of 3.72 kg/ m2 was obtained from ponds which were stocked with 20 fish / m2 and fed with homemade feed consisted of 60% wheat bran + 30% mustard oil cake +10% flour, while the highest net yield of 8.55 kg / m3 was obtained from cages stocked with 300 fish / m3 fed with the same feed from the same cultural environment. The lowest net yields of 2.34 kg/ m2 and 8.48 kg/ m3 were recorded from fish stocked at 30 fish/ m2 and 400 fish / m3 fed with the same feed from ponds and cages respectively. With the high survival rate the growth and yield of tilapia fish were found to be significantly influenced (p <0.05) by the cultural environment, stocking density and their interactions. Therefore the culture environment had a greater exerted effect on the production than the stocking densities.