Osteogenesis imperfecta (OI) is a genetic disease characterized by fragile bones, skeletal deformities and, in severe cases, prenatal death that affects more than 1 in 10,000 individuals. We report a case of a primigravida, a 24 yr old lady who presented in the emergency room of a secondary care hospital in Howrah, West Bengal, India (Silver Jubilee Matrisadan) at 36 weeks of gestation with breech presentation. Upon delivery by Em LSCS the Obstetrician & Neonatologist found that there was fracture in right femur and abnormally stunted left leg. Fracture femur during delivery was suspected. Radiological examination of both lower limbs showed fracture of right femur, with abnormal acute bowing of left femur with no associated shadow showing fracture haematoma. The neonate was transferred to a tertiary care centre for investigation and further diagnosis and management. Neonate was diagnosed to have Osteogenesis Imperfecta. This peculiar puzzling presentation which was primarily suspected as fracture of femur due to manipulation during breech delivery was subsequently diagnosed to be an undiagnosed case of osteogenesis imperfecta with intrauterine fractures

Candida fermentati SA3-7, a haploid yeast strain was treated by ultraviolet (UV) radiations and Dimethyl sulphonate (DMS) for enhanced invertase (EC 3.2.1.26) production. The UV induced mutagenesis did not produce any stable mutant with improved enzyme production. The culture was subjected to DMS treatment. The mutant DMS-4 obtained after exposure with 0.06 mg/ml of DMS for 45 min gave many fold increased enzyme production (34.12 U/ml) compared to the wild. After optimization of incubation time (48 h), sucrose concentration (5 g/l), initial pH (6.0) and inoculum size (2 % v/v, 16 h old), the enzyme production reached 45.65 U/ml with a remarkable >40 fold enhancement. On the basis of kinetic parameters markedly Qp (0.872 U/g/h), Yp/s (2.403 U/g) and qp (0.209 U/g yeast cells/h), it was concluded that the mutant was a hyper producer of enzyme and has a faster growth rate. The rate of volumetric production was 25 fold improved over the parental strain. The enhancement in the enzyme production is highly significant (HS, LSD 0.045, p≤0.05).

The present study involves assessment of water quality of Kshipra river by use of control chart, water quality index (WQI), physico-chemical and microbiological analysis. Samples were collected from five sites of the river for a period of one year. The main purpose of the study is to provide a baseline data regarding pollution control, management and improvement of water quality of this river before Mahakumbh 2016. Analysis of various parameters like dissolved oxygen (DO), chemical oxygen demand (COD), biological oxygen demand (BOD), total coliform (TC), fecal coliform (FC), turbidity, transparency, total alkalinity, total hardness, chloride, calcium was performed.WQI values ranged from 284.0-1112.34 and shows all study site to be under pollution stress. Results of the present investigation showed that water quality of the river is more deteriorated during summer followed by monsoon and winter season. Control chart model is applied for the first time in the analysis of water quality, as it provides a clear pictorial view about the pollution status of the river. The sample mean values in control chart cross lower and upper limits consistently in all seasons and at all study site, indicating very poor water quality. Higher pollution load was observed in Ramghat followed by Managalnath, Triveni, Mahidpur and Kshipra village study sites. According to CPCB water of Kshipra river is found to be of D class and river is observed to be under great pollution stress. Immediate remedial measures are recommended to control pollution and improve water quality of the river which is important for proper management and conservation of this holy river.

Features of Type A are common among physicians and may be related to the experience of stress. We aimed to assess the prevalence of features of Type A and the level of declared vs. objectively measured stress among young, healthy men and women studying medicine. 130 healthy female (age: 23±2; BMI: 20.9±2.4 kg/m2) and 71 male (age: 22±2 years; BMI: 24.3±3.3 kg/m2) medicine students completed the Polish versions of: the Framingham Type A Scale, The Perceived Stress Scale (PSS-10) and the Sense of Stress Questionnaire (SSQ, with 3 subscales assessing: emotional tension, external stress and internal stress). Moreover, we measured the level of cortisol (the ‘stress’ hormone) in saliva. Results in both questionnaires assessing perceived stress did not correlate with the level of cortisol (both p>0.05). In both genders, features of Type A were positively related to the perceived stress (PSS-10: accordingly, r=0.6 and r=0.5; SSQ: r=0.6 and r=0.6; all p<0,001), but not with the level of cortisol (p>0.05). Development of the pattern of behavior called Type A personality-behaviour might be related to the conviction of experiencing stress rather than to its actual level measured objectively. Such observation could be valuable for physicians who experience extremely high level of stress during their work.

Abstract: Taking a certain dense pattern test area in Daqing oil field as an example, the use of small layer contrast, sedimentary microfacies and single sand identification technology, combined with modern sedimentary model and the outcrop research results and cores, referred to c logging and dynamic data and empirical formula, densely well pattern anatomy and dyad well analysis, summed up internal architecture model of the point bar in the study area. And under the guidance of the model, the author provides the basis for further tapping the potential and development in oil field.

Dental caries (tooth decay) is one of the most important global oral health problems. Tooth decay can have a negative impact on activities of daily living and consequently on a person’s quality of life. Of the many species of microbes normally present in the oral cavity, Streptococcus mutans is the most significant bacterial group implicated in development of dental caries. Consequently, reducing the bacterial load is a practical prevention strategy. Various chemo-mechanical aids have been used towards achieving the goal. But many of the chemical constituents become disadvantageous due to various reasons like formation of stains and development of microbial resistance with prolonged use. As a result, researching and scientifically validating newer formulations becomes significant. This literature review briefly sums up the scientific basis of few indigenously used medicinal plants in India which have shown action against oral microorganisms like Streptococcus mutans. These studies have the potential to be converted into commercial preparations with appropriate field trials.

There has been various design methods for roller compacted concrete (RCC) pavement during a several decades. These design procedure are developed gradually. In this paper a 3D finite element (FE) model of RCC pavement has been developed. . In the validation step, the results of 3D modelling are compared with those obtained by theoretical approach. The comparison shows good correspondences. Due to the fact the theoretical approach uses 2D model in the formula, the 3D FE model results were slightly lower than the theoretical model. Using finite element software ABAQUS software, the paper investigated effects of changes speed in vertical displacement. In order to find the effect of speed in typical RCC pavement with the assumed properties in section 3, five partition for the applying load has created on the surface of slab. Vertical displacement at the bottom of the surface layer has been achieved for six different speed. Considering the obtained results of vertical displacement of the pavement for four assumed speed, the fitted curve is drawn with high accuracy.

Cloud Computing is one of the important name in the field of Computer and Information Science. Cloud Computing is actually need of the hour. Cloud Computing is an important platform which is deals with virtualization. This is a platform or more clearly an architecture which supports virtualization. And virtualization is including hardware, software, packages, utilities and applications that means whole IT infrastructure. Cloud Computing and its evolvement introduced so many facilities and services out of which demand based services treated as most important in many perspective. This paper is deals with several aspects of cloud computing; including so many demand based services for creation of healthy and sophisticated information infrastructure powered by advance technologies. Several facets reported in this paper as per the R&D undertaken in ISOAH Data Securities Pvt. Ltd and also will be incorporated in the doctoral thesis of the main researcher.

The study investigates the literary form of the Holy book—The Qur‘an. The book is explaining the principles of Islam— a religion of Muslim Umah. In the era and since the Prophet Muhammad‘s time, it was questioned that it is a book written by a poet. It has been under the keen study to know the language used in the Holy Qur‘an. The study explains the language of the Holy Qur‘an. The Qur‘an is not prose and that it is not verse either. It is rather Qur‘an, and it cannot be called by any other name. The Holy Quran is the reference book for more than 1.6 billion of Muslims all around the world. Extracting information and knowledge from the Holy Quran is of high benefit for both specialized people in Islamic studies as well as none specialized people. The word Qur‘an has never been used for any other book since long in the history of the universe. It has its unique form[1]. This study helps to introduce the reader to the language of the Holy Qur‘an.

Ketosis-prone diabetes (KPD) is a heterogeneous syndrome characterized by patients who present with diabetic ketoacidosis or unprovoked ketosis but do not necessarily have the typical phenotype of autoimmune type 1 diabetes. In this case report, we expose the difficulties in the diagnosis aetiology of A- β- ketosis-prone diabetes (KPD) in a 22-year-old North-African woman presenting with diabetic ketoacidosis. Her initial glycaemia was at 17.2 mmol/L and glycated haemoglobin (HbA1c) was moderately increased at 7.6% with no clinical evidence of other precipitating illnesses or stressful events. Her baseline and glucagon-stimulated serum C-peptide levels were below the detection limit at the time of admission. All anti-pancreatic antibodies were negative and pancreatic imaging was normal. Direct sequencing of HNF1A, HNF4A, INS, IPF1, NEUROD1 and PAX4 genes were performed and showed three mutations in HNF1A (I27L), NEUROD1 (A45T) and PAX4 (H321P). HLA typing showed the genotype DQB1*03- DRB1*11/DQB1*03-DRB1*13. Based on that data, type 1A diabetes mellitus (DM) could be excluded. However, criteria of fulminant type 1 DM are mostly filled but difficult to be confirmed and the MODY (Maturity Onset diabetes of the young) hypothesis could not be ruled out as other genes may be involved. Our observation highlights the difficulties of understanding the aetiology of A- β- KPD with sudden-onset although clinical, imaging, immunologic and genetic data are available.

Abstract: There are three facies areas, that are meandering river, delta distributary plain and delta front in the reservoir layer of the BY region of the Daqing oilfield. SⅡ81、SII21、SⅢ8 are typical sedimentary time units which are respectively belong to each facies area. We Used statistic analysis method to obtain the subtle variety of the three permeability parameters- Kv, Tk and Jk- to make the research of the in-layer microfacies controlling heterogeneity of typical channel single sandstone body. Research indication: The in-layer heterogeneity of typical channel single sandstone body, the meandering river facies area’s is relatively most serious, the distributary plain’s is medium, and the delta front’s is relatively weak.

Abstract: This study investigated correlational teamwork among Secondary Schools in Musoma Municipality using case study approach. A sample of 10 Secondary schools was randomly selected and 164 teachers, non-teaching staff and school leaders participated in the study by filling the questionnaire. Validity was established through expert judgment and reliability test yielded Cronbach’s alpha of .863 for teamwork, .885 for morale of work, .866 for leadership and .875 for communication. Descriptive Statistics, ANOVA and Pearson product moment correlational coefficient were employed to analyse research questions. General mean score of school stakeholders in all aspects of teamwork was between 2.50 and 3.49, meaning they agreed that there is tem work in their schools. Statistics yielded a significant difference in perception of school leaders, teachers and non-teaching staff on teamwork, school leaders having significantly higher mean scores than teachers. Results also revealed a positive and strong relationship between teamwork and morale of work and leadership. Moderate and positive relationship was also found between teamwork and communication. Following these findings, it is recommended that schools under investigation need to enhance good leadership and strive to increase morale of work among school stakeholders in order to increase teamwork spirit.

Abstract: Tight reservoir has become a hot spot of oil and gas exploration and development, meanwhile the study of pore structure is the core of the study of tight reservoir. Pore structure has a direct impact on the permeability of the reservoir. According to all kinds of pressure mercury parameters and permeability in correlation to determine pore throat size is the decisive factor of the reservoir permeability size, pore throat sorting and connectivity on the permeability of the influence is relatively weak.

Our study was carried out over 5 months from April 2014 to August 2014. Patients of uncomplicated cataract operated at tertiary care centre, Nanded by same surgeon with Manual small incision cataract surgery (SICS) with posterior chamber intra ocular lens (PCIOL) were studied. Objective is to find out co-relation between High IOP and topical 0.05% Difluprednate use on post-operative patients. Study Design was hospital based, prospective, observational Cohort study. Patients were started on topical antibiotic plus 0.05% difluprednate combination on first post-operative day and advised q.i.d. dosing. Then patients were followed for 6 weeks their IOP was measured by Goldmann Applanation Tonometer. Total of 56 eyes of either sex were included in the study. Our study showed that there is low risk of IOP rise in postoperative cataract patients i.e. 3.57% (2 out of 56 eyes) if schedule is followed. So our study concludes that strict following of dosing is necessary to get good outcome with difluprednate

Abstract: Heavy mineral analysis plays an important role in provenance analysis that determines the location of the source region, source spreading and feeding direction. In the detailed results of previous studies and on the basis of reading a lot of literature, this paper expounds the important role of the four heavy minerals analysis methods in provenance analysis include: the traits of heavy mineral, typomorphic characteristic, stability factor, etc., then, state the advantage and disadvantage.