The main objective of the study was to evaluate the possible analgesic and central nervous system (CNS) depressant effects of methanol (MMPL), petroleum ether (PMPL), chloroform (CMPL), dichloromethane (DMPL) and aqueous (AMPL) extracts of the M. paniculata leaves. Analgesic effect was evaluated by acetic acid induced writhing and hot plate methods at 50 and 100 mg/kg dose. The CNS-depressant effect was assessed by using open field, hole cross and head deep tests at 100 and 200 mg/kg dose. All the extracts had exhibited significant (Pb < 0.01, Pa < 0.001) analgesic and CNS depressant effects at dose dependant manner. AMPL showed maximum analgesic effect with 72.92% inhibition of abdominal writhing and 33.03% maximal possible effect (MPE) of paw licking time at 100mg/kg dose. On the other hand, CMPL had shown highest CNS-depressant effect with 93.80% inhibition in open field, 84.63% inhibition in hole cross and 81.54% inhibition (head deeping) in head deep test at 200mg/kg dose. Among the five extracts AMPL is a potent analgesics and CMPL is a potent CNS-depressant agents. These findings may unveil the efficiency of these extracts as analgesics and CNS depressant drug which may lead to develop a new phyto-medicine

Abstract: Scoliosis deformity is characterized as a lateral deviation of the spine in three-dimensions accompanied by axial rotation of the vertebrae. In this paper by surveying on the mathematical model of spine movement, we simulate the growth of scoliosis disease of a patient by using finite element method for vertebrae T1-T6 of spine. For this purpose by using Newmark method, we first deal the numerical solution of the given mathematical model. We will also explain the growth process of this disease by using geometric drawing in Matlab environment. Moreover, numerical simulations based on the mentioned process are presented.

Abstract: Slice interpolation in medical images is one of the important concepts in medical image processing in which many attempts have been made to improve it. In general, it is divided into two groups that are intensity-based interpolation and object-based interpolation. This article is an overview of object-based interpolation, based on image registration. Due to the various types of image registration and curvature registration as the latest one, interpolation is done on the basis of this type of registration. According to this, there would be an optimization problem which is solved by the use of Euler-Lagrange. In this regard, an optimization problem converted into a partial differential equation that is solved by using finite difference method. Then, by applying the solution an optimal displacement vector for moving the image is obtained.

Abstract: The Kadugolla community is very backward and even the economic position of men of this community is hopeless and pitiable. In such a scenario one can understand the plight of the women folk. But things have started to change in the recent times and the Kadugolla women have been able to lift themselves up from the perennial state of discrimination and inequality.

Abstract: Mucocele is a term used to describe the swelling caused by pooling of saliva at the site of injured minor salivary gland. Various treatment modalities have been present for the management of mucocele, These include excision by a scalpel, laser ablation (CO2, Er, Cr:YSGG), electrosurgery, cryosurgery, medication (gamma-linolenic acid [GLA]), micromarsupialization. This case report present definitive management of lip mucocele.

Abstract: Discoveries of new-to-science species have rendered outdated the last published list of Jaltomata species of Peru.We recognize eight Jaltomata species in Department Lima: J. andersonii, J. aspera, J. bicolor, J. contorta, J. dentata, J. hunzikeri, J. propinqua, J. umbellata, and J. sinuosa. The latter has not been collected in Department Lima but was included in the key because it is likely to grow in Department Lima. Fruits of at least five of these species (J. aspera, J. bicolor, J. dentata, J. propinqua, J. umbellata) are eaten by people. Two species,J. aspera and J. umbellata, have copious red/orange floral nectar. In lomascommunitiesJ. aspera, J. hunzikeri and J. umbellataflower July–October.However, in the AndesJ. aspera, J. bicolor, J. dentata andJ. propinquaflower mostly from December–April. There are no recent collections of J. contorta and J. hunzikeri and these species may be extinct.

Abstract: In this paper, we propose a non-monotone trust region method for solving equality constrained optimization problem. Unlike the traditional trust region methods, our algorithm uses a new non-monotone strategy. Theoretical analysis indicates that the new method preserves the global convergence under some mild conditions.

Powder metallurgy is emerging day by day as a concrete solution to the new age scientific problem. Every metal has its own characteristics and limitations. Powder metallurgy confluences the good characteristics of different metals into one product, but requires a correct combination of various sub-processes associated with main process. Powder metallurgy conquers the power of 4 P,s i.e. Precision as producing near net shape, Performance as fast and consistent , Productivity as higher output and Price as low considering lesser secondary operation needed. Some important mechanical properties of the different Ti-Nb alloys are analyzed in relation to the human implants. This paper reviews different sub processes of powder metallurgy and their combination for the biomedical application of different power metallurgy products. Papers also describe some advancement in manufacturing techniques and powder metallurgy sub processes that enhance the behavior of materials for human implants.

Urinary schistosomiasis though a neglected disease is endemic in many rural communities in Nigeria and is second only to malaria. The present study was carried out to determine the current status of urinary schistosomiasis in Ilie, a rural community in Southwestern Nigeria. Urine samples were collected from 320 school pupils (4-15 years old) and examined for ova of Schistosoma haematobium. Out of the 320 urine samples examined, 131 (40.9%) had ova of S. haematobium. The prevalence of urinary schistosomiasis between the male (42.8%) and female (39.0%) participants was not significantly different (p = 0.49) but prevalence increased significantly with increase in age (p = 0.002). The overall geometric mean intensity of infection was 38.2 eggs/10 ml urine. The intensity of infection was not dependent on sex (p = 0.79) or age (p = 0.69). The overall prevalence of haematuria in this study was 26.3%. The prevalence of haematuria was independent on sex (p = 0.72) but varied significantly with age (p = 0.01). Haematuria was significantly associated with urinary schistosomiasis (p < 0.001, OR 37.1, 95% CI 19.4 - 71.0). This study shows that urinary schistosomiasis is quite endemic and still actively transmitted in Ilie and appropriate control measures are highlighted

In this laboratory a novel series of 1-phenyl-3-[4-(2,4-dithio-3-allyl-5-substituted-1,3,5-triazino) aminophenyl]-prop-2-ene-1-ones (IIa-e) was synthesized by the isomerization of 1-phenyl-3-[4-(2-allylimino-4- substitutedimino-1,3,5-dithiazino)aminophenyl] prop-2-ene-1-ones (Ia-e)in 10% aqueous ethanolic sodium bicarbonate medium. The structure of all the synthesized compounds was justified on the basis of chemical characteristics, elemental analysis and spectral analysis.

Management of a case of internal root resorption is a challenge to the endodontists.Internal resorption of teeth is an insidious process and is generally found in teeth with previous history of trauma.It may occur in cases with chronic pulpal inflammation, following caries or due to trauma in the form of an accidental blow. Internal resorption is very often noticed in anterior teeth, due to their susceptibility to trauma. However, it may be seen in posterior teeth, most likely because of carious involvement of the pulp. Early diagnosis, removal of the cause, proper treatment of the resorbed root is mandatory for successful treatment outcome. This case report describes the management of theresorptive defect in the apical 1/3rd whichwas treated nonsurgically with thermoplastized guttapercha technique. A six-month follow up demonstratedclinically asymptomatic and adequately functional tooth, with radiographic signs of healing

The experiment was conducted with 34 local rice genotypes with one check varieties at the Sher-e-Bangla Agricultural University experimental field to study characterization and genetic diversity of 35 local rice genotypes and to find out the association among the genetic characteristics. PCA showed the highest inter-cluster distance was observed between the cluster II and V (46.71) followed by III and V (46.40) and IV and V (45.43). Genotypes from these three clusters may be involved in hybridization as wide genetic variations exist among the groups. Cluster IV exhibited the highest intra-cluster distance (38.36), while the lowest distance was observed in cluster V (23.09). Further study of this experiment is needed in different locations of Bangladesh for accuracy of the results obtained from the present experiment. Considering diversity pattern and other agronomic performance lines G-10, G-13, G-15, G-18 and G-24 could be considered suitable parents for efficient hybridization in future.

Alternative therapies for the alleviation of chemical/xenobiotic-induced metabolic aberrations and risk factors for cardiovascular disease have been inadequately explored, despite their rich cardiovascular protective bioactive constituents. The aim of the present study was to accurately evaluate the effect of Cymbopogon citratus extract on gasoline-induced oxidative stress, hyperglycaemia, hyperuricemia, dyslipidaemia, and atherogenic index of plasma (AIP) in rats. Seventy-two female Wistar albino rats were segregated into six groups (n = 12 per group). The rats in group 1 served as controls, while animals in group 2 were exposed to gasoline vapour (GV) alone for 35 days. Rats in groups 3, 4, and 5 were exposed to GV and co-administered 500 mg/kg, 1000 mg/kg, and 1500 mg/kg C. citratus leaf extract, respectively, once daily for 14 days. Rats in group 6 were exposed to GV and co-administered 200 mg/kg vitamin C for the same time period. The results showed that group 2 had significantly higher glycaemic levels, lipid parameters (TG, T-chol, and LDL-C), uric acid (UA), MDA, and AIP and significantly lower (p < 0.05) HDL-C than group 1. Co-administration of C. citratus leaf extracts in groups 3, 4, and 5 and vitamin C to group 6 significantly lowered blood glucose levels, UA, lipid parameters MDA and AIP and simultaneously increased serum HDL-C in a dose-dependent manner. C. citratus leaf extract has an ameliorative effect against GV-induced oxidative stress, hyperglycaemia, hyperuricaemia, dyslipidaemia, and AIP, probably mediated through its varied bio – constituents and their activities

Recently in this laboratory 1-substituted-2-thio-4-amino-6-methylformamidino1,3,5-triazines(XIIIa-r) were synthesised by isomerisation of 2-substituted imino-4-amino-6-formamidino-1,3,5-thiadiazines (XIIa-r) successfully by refluxing with 10% aqueous ethanolic sodium bicarbonate medium. The structure of all the synthesized compounds was justified on the basis of chemical characteristics, elemental analysis and spectral studies.

Since thirty years of reform and opening up in China, the number and size of small and medium-sized enterprises (SMEs) to achieve leapfrog development, it’s an important part of China's social economy and has great contribution to the economic development of China. However, in recent years the development of small and mediumsized enterprises are also facing many constraints, especially the financing problem of SMEs is an important obstacle to the healthy and rapid development of SMEs, in formal finance can not effectively solve this difficult situation, this is a good positive role to solve the private lending flexible lending to small and medium-sized enterprises financing dilemma. In the study of private lending to solve the plight of small and medium enterprises beneficial effects at the same time, we must also pay attention to the adverse effects of the small and medium-sized enterprise, put forward reasonable suggestions of private lending market norms, help small and medium-sized enterprises of comprehensive and rapid development.