The effectiveness of processes of life insurance companies is the prime concern for policyholders to choose a particular insurance company. Here researcher attempts to analyze the effectiveness of process related strategies of public and private life life insurance companies in perambalur district with the objectives of analyzing claim settlement time, ease of claim settlement formalities and policyholders’ dependence of insurance agent or insurance company employee for claim settlement. Here researcher adopts descriptive research design and used wellstructured questionnaire for data collection. 100 samples each from both public and private life insurance companies are collected using simple random method. From the data analysis it is concluded that public life insurance company is effective in process related strategies than private life insurance companies.

Medical devices can be categorized into two categories which is invasive and non-invasive method. Invasive method needs medical device to be inserted into patient body regarding to check or do the treatment on the patients. However, the non-invasive method is a way to check the health condition from the outside of the body. A common non-invasive medical device is Heart rate monitor. The function of the Heart rate monitor is determining heart rate (i.e.) beats per minute. The main aim of this work is to develop a portable device which helps to record heart rate of a person. The heart rate also referred as pulse rate, has been recognized as a vital parameter since beginning of medicine, and is directly related to person’s cardiovascular health. Heart rate or pulse recording is the most important vital parameter which helps the individual as well as doctor to spot out developing health problems. Using Heart Rate Monitor (HRM) is a more accurate way to monitor heart rate than manually taking your pulse at carotid of radial pulse. A HRM detects the electronic signal of heart and automatically computes the heart rate in BPM. Infrared light emitting diode (LED) is used to transmit the light and phototransistor works as a receiver. The Infrared (IR) sensors used uses the principle reflectance plethysmography (PPG) to sense the pulse signal from finger tip. The sensor output is read from the Arduino board, computes the BPM and display the instantaneous heart rate on LCD display module. Based on the above principle, a portable heart rate device using Arduino microcontroller is developed.

In the present work, two simple and sensitive UV spectrophotometric methods have been developed for the quantitative estimation of Metformin Hydrochloride and Benfotiamine in combination using bulk and pharmaceutical dosage forms. Method A is Simultaneous equation method which involves measurement of absorbance at selected wavelength and solving the simultaneous equation to calculate the amount of drug present. Distilled water was used as the solvent for the analysis of both drugs. Two wavelengths 230 and 246 nm were selected for the estimation of Metformin Hydrochloride and Benfotiamine. LOD for Metformin Hydrochloride and Benfotiamine were found to be 0.03µg/ml and 0.27µg/ml respectively. Method validation was done as per ICH guidelines. Method B is Absorbance ratio method which involves, formation of Q-Absorbance equation at 239 nm (isoabsorptive point) and 246 nm (λmax of Benfotiamine) in distilled water. The Linearity lies between 2-16 µg/ml for Metformin Hydrochloride and 2-18 µg/ml for Benfotiamine with r2=0.999 and 0.998 respectively. LOD for both drugs were found to be 0.16 µg/ml and 0.3 µg/ml respectively. Method validation was done as per ICH guidelines

The research report is used as a simple and precise method/ procedure of measuring and determining the convergence angle of final constructed dies. A random samples selection of 30 dies from School of Dentistry Taibah University students was taken. All the 30 preparations were accomplished by 3rd, 4th and 5thyear dental student under standard and regular clinic situations and at the lab. A variety of 4 to 10 degrees of convergence is recommended as optimal. The average taper of groups in this study, measured were substantially greater or more than those recommended. Many of the recently published research on the subject agree with outcomes and the values obtained in our analysis.

Hearing plays a key role in learning to talk. Early screening of newborns for hearing impairment is essential as treatment is most successful when identified early. The study assessed the challenges associated with screening and early detection of hearing impairment among children in the Kumasi metropolis and focused on the services available for screening of hearing impairment among children and the effects of the challenges of screening and early detection of hearing impairment. The study employed a qualitative approach. Purposive and convenience sampling were used to select 15 participants. An interview guide was adopted to capture the responses of participants on voice recorder. Thematic content analysis was used to analyse themes generated from the data according to the objectives. The study found that, hearing screening services for children included OAEs, pure tone testing, behavioral assessment and school outreach programs but health personnel are faced with challenges in undertaking these services. Challenges such as lack of enough funds, insufficient tools and equipment, few numbers of health personnel and low patronage of hearing screening services limited health personnel’s ability to provide effective hearing screening services to children. The study therefore recommends that the ministry of health constructs audiology units in every region in Ghana and supply the units with the tools and equipment needed for work. The study further recommends that, the ministry of health in collaboration with ministry of education should assist in training more audiologists and make school screening programs a long term national policy.

Most public pre-school centres in Kenya have stalled programmes marked by irregular and delay of teachers’ salaries, inconsistent feeding programmes, poor infrastructure and unclear policy guidelines. It is clear that financial management strategies are crucial for efficiency to be realized in finances in ECDE centres. This study was guided by the following objectives: . To establish existing planning strategies in the financing public pre-school education and to examine alternative planning strategies for financing public pre-school education in Eldoret East Sub-County. This study adopted a descriptive survey design. The study targeted 1 sub-county education officers, 174 Head Teachers, 174 Pre-school teachers and 174 SMC chairpersons in the Eldoret East Sub- County. It used a purposive sampling for the 1 sub-County educational officers and simple random sampling for the 52 Head Teachers, 52 Pre-school teachers, 52 and 52 SMC chairpersons. The researcher used questionnaires and interview. Data was presented using tables and figures. The study findings indicated that there was a significant relationship between planning strategies employed and financing preschool education. The study recommends that there is need for ECDE management committee to plan for resources early enough before spending to curb waste.

Single Cell Protein (SCP) can be obtained from various microorganisms by growing them on a number of types of substrates, including industrial products waste. This work focuses on non-conventional yeast Yarrowia lipolytica, and its application in the process of production of valuable components like SCP and amino acids. It also analyses the possibility of using obtained biomass as a dietary supplement for humans. Y. lipolytica is nonpathogenic to humans and has been approved for use in several industrial processes as it is generally recognized as safe (GRAS). The results of our analyses suggest that the Y. lipolytica A-101 – a strain growing in biofuel production waste is a good candidate for a source of high-quality yeast protein (40-50% of dried biomass) and exogenous amino acids (phenylalanine 3.9 g, isoleucine 4.4 g, leucine 6.8 g, lysine 7.0 g, methionine 1.2 g, threonine 4.8 g, tryptophan 4.7 g, valine 5.3 g/100 g of protein). Y. lipolytica A-101 biomass has also very low nucleic acids concentration (below 1%) due to activation of endogenous nucleases in the final stage of the stationary phase. These enzymes reduce the amount of nucleic acids in this biomass from a high level to one acceptable for human consumption. Moreover, Y. lipolytica A-101 biomass is safe and digestible since the yeast cells get killed in the drying process and has no leavening powder with destroyed cell wall. Y. lipolytica A-101 can be used as a nutritional supplement in human diet when an increased intake of amino-acids and SCP is required.

The government work report is a kind of style with Chinese characters of language expression. Therefore, when translating it, the translator must first understand the source language’s expression and analyze the discourse in order to make effective language conversion. Cohesion is one of the important methods of discourse analysis. In this paper, the author, taking 2017 government work report as an example, analyzes the application of discourse cohesion in government work report, emphasizing the importance of cultivating the ability of intralingual understanding and the awareness of cohesion in the process of Chinese to English Translation.

This paper contributes to an understanding of the main factors and actors that create the imperative for educational change in the six member countries of the East African Community (EAC) and how governance dynamics reflect on their policy positions. The method of study is qualitative and uses mainly existing literature as a synthesis. The study notes that the main drivers of educational change in the region are national and political transformation agenda; foreign aid conditionality; the advent and revival of the East African Community; and patronage, clientelism and corruption inherent in the neo-patrimonial set-up of the state. The member countries of the bloc initially drew upon the imperative of nationbuilding back in the 1960s to assign value to educational change as intertwined with Independence from colonial rule. Orthodox reform later assumed greater prominence in the 1980s and 1990s as aid conditionality drastically undermined gains made in educational expansion. Reforms undertaken in late 1990s and 2000s have been in response to the quest for democratisation in East Africa. Amid the clamour for policy convergence on educational change, there is need for a regionwide process of mutual policy borrowing, considerable harmonisation of curricula for secondary & higher education, and increased student and staff mobility. The study concludes that the history of state formation, political competition and statesociety relations in the EAC points to a complex variable of macro policy convergence in educational change and governance that calls for consummate tact as the region seeks a market-mediated identity and contemplates political federation.

Gaussian Mixed Model (GMM) has seen an increase in terms of usage especially to tackle the issue or problem of fraud activities in telecommunication industry. Like any other methods, GMM has its equal share of problems related to the maximum likelihood estimation and the determination of the number of components in GMM. In this paper we will highlight solutions to the said problems such as Expectation Maximization (EM) algorithm and the methods that are normally used to determine the number of components in GMM, which include the most recent research work done by the authors using Kernel method and Akaike Information Criteria (AIC); and the successful derivation of hypothesis testing in the determination of the number of components in GMM. The said derivation has never been attempted before due to the difficulty and complexity of GMM, as exemplified by the use of EM algorithm in solving its maximum likelihood estimation problem. The performance of the hypothesis testing, which is positive and promising despite using different percentage of overlapping; and the comparison of hypothesis testing to AIC, which produced conflicting results under certain conditions will also be highlighted

Vinculin is one the most common proteins that have been studied commonly in recent years. Vinculin has anti-tumor effect and loss of vinculin causes development of many cancer types. Because of this Vinculin is a marker and it shoulde be evaluated for invitro and clinical studies. LC/MS based proteomics is the main tool to analyze hundreds of proteins in very short time because it offers high sensitivity and accuracy. Today nano LC is the min tool for LC/MS proteomics researches but UPLC/MS based systems have been developed and offered more robust and easy way for proteomics. In this study we used normal flow UPLC/Q-TOF method to analyze caco-2 colon cancer cell line. One of our targets for this study was to identify Vinculin as a cancer marker. We digested proteins from caco-2 cells and analyzed with UPLC/MS. Recorded MS/MS data was used with Maxquant bioinformatic system. We identified 5 unique peptides that belonged to Vinculin. We used 20 ppm mass tolerance for amino acid sequence matching with uniprot human database. We made three raplicate to observe identification reprocubility. Also We used label free quantification method and calculated vinculin intensity

Labor union is one apex body of labor which is established with the purpose of advocacy and bargaining for the rights and benefit of labor. Union itself is power which can discuss with government and non-government organization for the betterment of labor. The labor union advocates on the different types of needs and right of labor, but the study has explore the role of labor union in promotion of physical facilities for workers of manufacturing industries of Bara and Parsa district of Nepal. In total 385 workers were selected randomly for the structured questionnaire survey. The statistical analysis of eight indicators measured in the field to know the status of physical facilities shows that in total only 39.68% workers agreed that labor union had played the effective role to manage the physical facilities for labor union which is not satisfactory result on the basis of objective of labor union. So, the role of labor union should be more effective and need to develop the new strategy of their action.

This study was aimed to investigate the association between thyroid disorders and lipid profile in 122 patients (100 females and 22 males ) referred to the Specialized Center for Endocrinology and Diabetes at Al –kindy Hospital in Baghdad . For comparison, 60 healthy individuals (31 females and 29 males), who had no thyroid disorders, were also included in the study. Blood samples were collected from both patients and the healthy individuals. Enzyme Linked Fluorescent Assay (ELFA) technique through using Vitek Immuno Diagnostic Assay System (VIDAS) was applied to measure levels of the thyroid hormones (tri-iodothyronine T3, tetra-iodothyroxine T4) and thyroid stimulating hormone (TSH). From the results obtained, patients were classified into three groups: 40 were considered as belonging to the controlled * group ( 26 females and 14 males), 57 to the hypothyroidism group (52 females and 5 males) and 25 belonged to hyperthyroidism group ( 22 females and 3 males). Females constituted the vast majority of both healthy and thyroid disorders patients with percentages of (51.7%) and (81.96%), respectively. The results also declared that there was a correlation between increasing the cholesterol level and decreasing level of high density lipoprotein (HDL).

In this paper, we build a formal, rigorous economic model for foreign language learning, taking language input and language output as two crucial factors working jointly to generate language competence. The central idea behind our model is that the learner, constrained by limited resources, is confronted with a tradeoff between input-oriented training and output-oriented training. First, one major contribution of our modeling lies in its effort to reconcile the Input Hypothesis with the Output Hypothesis in the literature by showing that one important aspect of the learner’s learning strategy, i.e. the input-output mix, is crucially dependent on the learning environment. Second, our modeling provides guidelines for data based empirical research, where the partial effects of the variables of interest can be estimated and hypotheses on the directions and magnitudes of the effects can be tested, econometrically. Third, our modeling also provides insights that can assist language instructors in making and fine-tuning teaching strategies.

Antimicrobial resistance reduces the effectiveness of the standard treatment and also increases the risk of spreading the disease to others. Therefore, there is an urgent need for the development of new class of antimicrobials. In such an attempt, benzothiazole schiff base hybrids synthesised were evaluated for antimicrobial potency against E. coli, S. typhi, S. aureus, E. faecalis, K. pneumonia, P. aeruginosa, C. albicans, C. tropicalis, and C. krusei and also an attempt was made to understand their molecular mechanism of action. Some of the benzothiazole schiff base hybrids have exhibited excellent antimicrobial activity with MIC of 3.91µg/ml against S.aureus, P.aeruginosa and E.coli in comparison with the standard drug ciprofloxacin. The molecular mechanism of action of benzothiazole schiff base hybrids was elucidated in both intact bacterial cells and plasmid DNA. The potent antimicrobial activity of the hybrids may be due to membrane perturbing mode of action explicated by membrane depolarization assay and fluorescent assisted cell cytometry (FACS) study on intact bacterial cell. However, the activity may also be due to the intracellular mode of action explicated by DNA cleavage study on plasmid DNA