Oncogenesis is a very complex and multistep process with many factors involved. Among the various cancers viral oncogenesis constitutes about 12%. The human population has been plaqued by viruses particularly viruses with oncogenic potential. Worldwide, viruses cause numerous miseries ranging from flu to complex cancers. A noteworthy few among them are caused by oncoviruses such as Human papilloma virus, Hepatitis B, Hepatitis C, HTLV-1, EBV. Among these viruses Human papilloma virus and Human T Lymphocyte virus have direct oncogenic potential whereas HIV, EBV, Hepatitis B and Hepatitis C have indirect oncogenic potential. In this review, we aim to discuss briefly about the pathogenesis of the most commonly 6 occuring oncoviruses and their oncogenic potential.

This study investigates the effect of tax audit and investigation on the revenue generating capabilities of Federal Inland Revenue Services (FIRS), a study of Port Harcourt branch of Federal Inland Revenue Services. The two research questions that guided the research include; to what extent does functional tax audit and investigation department of FIRS influence its revenue generating capabilities; and to what extent does ineffective tax audit and investigation exercises affect the revenue generating capacity of Federal Inland Revenue Service. The population of the study consists of the staff members of the Federal Inland Revenue Service, and professional accountants Port-Harcourt. A Simple random sampling technique was adopted in distributing 100 copies of questionnaire, out of which 80 copies were returned. Presentation and analysis of primary data collected with questionnaire were done using tables and simple percentages. The study revealed that functional tax audit and investigation department, to a considerable extent influences the revenue generating capabilities of Federal Inland Revenue Service. Besides, ineffective tax audit and investigation exercises, to a great extent, weaken revenue generating capacity of Federal Inland Revenue Service. The study recommends the need to strengthen tax audit and investigation department and to ensure its optimal performance, a degree of autonomy should be granted to this department to enable it carry out its responsibilities effectively as specified in Federal Inland Revenue Service Establishment Act 2007.Thorough, regular, effective and efficient audit and investigation exercises should be put in place through the employment of competent professionals considering the importance of tax audit and investigation processes. The study equally concluded that effective and efficient audit and investigation exercises together with functional tax audit and investigation department would strengthen considerably the generating capabilities of Federal Inland Revenue Services (FIRS).

HIV-related cutaneous manifestations are very common and can be easily detected. If studied systematically, they can serve as diagnostic and prognostic markers. It is aimed to study the skin biopsies of various dermatological manifestations that occur in HIV seropositive patients attended to a tertiary care centre. This is a prospective study of cases of 104 were studied histopathologically who were Seropositive for HIV. Majority are of 31- 40 years (32.69%), and closely followed by the age group 21-30 years (28.84 %). Patients of both sexes were affected with males females ratio of 1.19:1. The most common cutaneous manifestation observed was Papulosquamous lesions with 37.5% cases and in this 53.84% cases were pruritic papular urticaria. Infections observed were 25%, among which majority were of bacterial infections. Drug reactions were observed in 15.3% of cases and majority of patients presented with Stevens Johnson syndrome. Dermatitis was seen in 11.53% of patients and seborrheic dermatitis is the common non-infectious dermatosis. Other cutaneous manifestations like vascular involvement, neoplasms contributed minority of cases. Most of the patients presented with cutaneous manifestations having CD4 count in the range of 350-500. It was conclude that the dermatological lesions are extremely common and may present with early, severe, unusual and atypical manifestations in the course of HIV infection. Awareness of the varied pattern of these manifestations would help in the early diagnosis and management of HIV infection, which would in turn decrease the morbidity and improve the quality of life of HIV-infected patients.

Abstract: Glucose 6 phosphate dehydrogenase (G6PD) deficiency and Neonatal Hyperbilirubinemia. The Prospecutive study was conducted between June 2017 to June 2018 among icteric neonates in Maternity and Children Hospital, Nejran, Saudi Arabia. A total of 200 icteric neonates were included in study, who were admitted in nursery during study period. Each baby was tested for Complete blood count, Reticulocyte count, ABO and Rh blood types, Direct antiglobin test and quantitative G6PD estimation. Out of 200 icteric neonates 56( 28%) were found to be G6PD deficient and 144 (72%) had normal enzyme activity.38.7% were males and 12.3% were females among G6PD deficient neonates. Fisher exact test is 0.00 which is highly significant as p<0.001. None of them had kernicterus. Haemoglobin and Reticulocyte count in G6PD deficient neonates is statistically significant as p<0.01as compared to G6PD normal neonates. Since the Prevalence of G6PD deficiency in our neonates was relatively high. Early detection of this enzymopathy regardless of sex and close surveillance of affected newborn may be important in reducing the risk of severe hyperbilirubinemia.

This study examined the ecotoxicological evaluation of commercial fish pond in Mgbuoba, Port Harcourt, Rivers State Nigeria using water quality and gross anatomical assessment of Clarias gariepenus, using African Aquaculture Centre (ARAC) as a reference site. In this research the following were done: Gross anatomical assessment of the farmed fish which comprised of condition factor (CF), Organo-Somatic Index (OSI) and Health Assessment Index (HAI) and physico-chemical properties of pond water. The chemical assessment involved environmental water quality index (EWQI) and heavy metal assessment. The gross anatomical assessment involved the sampling of twenty table-sized fish harvested from the Mgbuoba commercial fish pond which were compared with ten table-sized fishes of the same specie harvested from an aqua-cultured centre, ARAC. The EWQI of the commercial fish pond was considered to be of a fair quality, condition factor recorded showed that fishes from Mgbuoba were in better condition than that of ARAC, health assessment index was poor in fishes harvested from ARAC. The organosomatic index showed that Mgbuoba fishes had a high mean values for Gills and Liver respectively. Using one-way Anova statistical analysis, no significant difference (p>0.05) were noted between Mgbuoba commercial fish pond and ARAC. It is suggested that at intervals the health status and water control should be examined/analyzed to keep a suitable habitat for the fishes and make consumption safe humans.

The development of tourism is essential since it increases the foreign exchange. The adequate attention to the tourism drives the progress of tourism related products and services. Several studies have shown that the role of destination image influence the tourists to visit. The purpose of this study is to determine the forming components of destination image with a quantitative approach. The research population consists of the most visited destinations in Indonesia. Questionnaires are distributed in three cities that represent the most visited places by tourists in Indonesia. According to the statistical calculation, the amount of sample that can be used is 167 people. The results reveal that some aspects significantly influence the destination image. The influencing aspects are lodging facility, quality of food and relaxation experiences. This finding implies that there should be some improvements in lodging facilities, the quality of food and relaxation experiences to enhance the destination image.

Hepatitis A virus (HAV) infection is one of the important causes of hepatitis in developing countries. It is transmitted through feco-oral route. They pose major health problems. To determine the prevalence of HAV in patients presenting with acute viral hepatitis. Serum samples of the patients presenting with fever, nausea, vomiting, and jaundice were collected and analyzed by using commercially available RecombiLISA ELISA kit for the detection of immunoglobulin M (IgM) against HAV. A 20 months retrospective study was conducted in the Department of Microbiology, Shri M. P. Shah Govt. Medical College, Jamnagar, Gujarat (India). Of the 532 serum samples subjected to RecombiLISA ELISA for detection of anti-HAV IgM in patients, 157 (29.51%) were found to be positive. The prevalence was found to be more in male patients than in female patients, that is, 81(51.59%) and 76(48.41%), respectively, and was predominantly seen in the 6–15 years of the school-going age group. Peak cases were found in the monsoon season. Regular monitoring of clinical, serological and molecular characteristics would help in understanding the epidemiology of HAV and in planning the intervention studies.

The research entitled "The Influence of Motivation, Compensation, Job Satisfaction Against Nursing Turnover Intentions At JTS Hospital" aims to know, describe, measure and analyze the effect of motivation, compensation and job satisfaction on turnover intentions of nurses at JTS Hospital. The subjects of this study were 62 nurses who worked in Nursing Field Hospital JTS. The data obtained were analyzed by using multiple linear regression with the help of SPSS program version 24. There is significant influence of motivation variable, compensation variable and job satisfaction variable to nurses turnover intentions variable working at JTS Hospital. It is suggested to the management of JTS Hospital to evaluate and develop better policies and compensation system to fulfill the need and work expectation factors that encourage motivation and job satisfaction of the nurse to generate loyalty and productivity and it is expected to improve the nurse turnover intentions at JTS Hospital.

Mature cystic teratomas comprise of 10-20% of ovarian neoplasms. Malignant transformation in a dermoid cyst occurs in 0.17-2% of cases. Primary ovarian melanoma arising in a dermoid cyst is an extremely rare entity. It must be differentiated from a metastatic melanoma which is more common. A fifty nine year old female presented with lower abdominal pain and heaviness. A right adnexal mass was noted on Computed tomography (CT) scan. Left ovary and uterus were normal. She underwent a right salpingo-oopherectomy. Histopathological examination along with immunohistochemical analysis and clinical correlation serves the diagnostic purpose and surgery with adequate margin clearance plays an important role in management. We report a rare case of primary malignant melanoma arising in a mature cystic teratoma.

Bangladesh has the second highest prevalence rate of child marriage. Atthe village Montolaof Monohardi upazilain Narshindi district, child marriage is still a bad custom. NGOs are not successful enough with their traditional practices. Actually, creativity is in need at this juncture. This study, which is dominantly qualitative in nature, suggests some creative direct marketing approach. With the help of focus group discussion and direct observation, this study found some core causes of child marriage e.g., poverty, lack of education and social norms or tradition and therefore, suggests successful girl’s voice, union parisad’s seminars on health complicacy due to child marriage, melodious songs in hut on hutbar, drama or jatrapala etc.

This study was aimed at comparing the height predicted from ulna lengths in the adults (aged between 20 to 50 years old) from the two different ethnic groups. Analysis of stature of 600 healthy males and 600 females from Ikwerre and Kalabari ethnic groups, both in Rivers State, Nigeria, Height was measured using a stadiometer, while ulna length was taken with a sliding vernier calliper. The measurements were recorded in centimetres to the nearest 0.1 cm. A multiplication factor i.e ratio of the stature to the respective physical measurements was then calculated for each measurement. The multiplication factors were multiplied with the ulna length to give the estimated value which correlated with the measured stature. The mean male Ikwerre stature was 173.1 while the female was 160.77. The mean stature for Kalabari male was 166.83, while the female was 158.83. Correlation coefficient in the study for Ikwerre males is 0.96 and females 0.997 I and that of the Kalabari males is 0.996 and females 0.996. Regression coefficient for Ikwerre males is 7.89 and females 6.48 and that of Kalabari males is 6.31 and female 6.15. The observed data was subjected to „z‟ test for correlation coefficient. The value for „z‟ test was found to be statistically not significant. It was concluded that ulna length can be used as a surrogate in measuring height. Also, there was no significant difference in the stature of the two different tribes.

Research on Local Wisdom, Innovation and Talent of Management on SME Competitiveness by using quantitative approach and survey method. The sample of the research is 61 people. Data were collected using questionnaires with Likert scale 1-5. The data analysis technique is Generalized Structured Component Analysis. The results of this study prove that: 1) the Local wisdom has direct and positive impact on competitive advantage of SMEs, 2) innovation has direct and positive impact on the competitive advantage of SMEs, 3) Talent Management has directly and positively impact on competitive advantage of SMEs, 4) Local Wisdom has direct and positive impact on Talent Management, 5) Innovation has direct and positive Affect onTalent Management, 6) Local Wisdom has direct and positive impact on competitive advantage of SMEs through Talent Management mediation, and 7) Innovation has directly to competitive advantage of SMEs through Talent Management.

In the present world, due to tremendous development in technology, a huge amount of information is available everywhere. Therefore, it is difficult for the users to understand the main content of the entire document as it takes a lot of time. In this work we use extractive text summarization which uses a method to give the version of summary for one or more file or document. Here we give an approach that maps sentences to nodes of a hierarchical ontology. Ontology explains what exists in a particular domain. For the ontology creation, vocabularies are collected. It is used as background knowledge and helps to find the related meaning of the terms which occur in the source documents. Text mining is the technique from which high quality information is derived from text. Clustering is a significant task. The clustering method groups similar or related terms into a single group. In the first stage, data collection takes place. The preprocessing stage includes stemming and stop words removal.TF-IDF process occurs after which clustering takes place. In the ontology creation, first the determination of the main sub topics of the article of interest is done. We classify sentences to nodes which have a predefined hierarchical ontology. Each ontology node has bag-of-words from a web search. We represent sentences by sub trees that permit to apply measures of similarity and find relations between sentences. The ontology used in this work is not domainspecific; it does not require labelled data. this work can be extended to topics focused on summarization framework to news articles or blogs and to also to various machine learning approaches

In the present study, the isolated compound Punicaflavone (PF) from the methanolic flower extract of Punica granatum (Linn.) was subjected to toxicity assessment in Wistar albino rats. Sub-acute toxicity studies were carried out by oral administration of the PF from Punica granatum (Linn.) for a period of 28 days at different dose levels of 50, 100 and 200mg/kg body weight. No major changes in body and organ weight, behavioural, haematology and histology were observed at the end of 28 days of daily oral administration. Biochemical parameters such as the levels of Glucose, Protein, Urea and Creatinine in serum were found to be well within the normal limits. Histopathological examination of the major vital organs (heart, liver and kidney) revealed no significant pathological alterations in the treated group of rats. The sub-acute toxicity studies of the PF showed no mortality and no symptoms of toxicity or behavioral changes at the maximum dose (1000mg/kg). The results indicate that the PF is safe up to a dose of 1000 mg/kg.

The study examined the prevalence of HIV among pregnant women in three selected hospitals in Port Harcourt namely; military hospital, St. Margaret maternity home and El-Joe dam specialist hospital. This study was aimed at determining the Prevalence of HIV/AIDS among pregnant women in Port Harcourt, Nigeria. The population of the study was all the pregnant women that registered for antenatal at the three selected hospitals. The sample size was 400 randomly selected. 300 pregnant women were sampled at Military hospital, 50 each at St. Margaret maternity home and EL-Joe dam specialist hospital. The “prevalence of HIV /AIDS a close-ended questionnaire” used to collect data. The results were tabulated. The blood sample for the test was collected by vein puncture into EDTA. The confirmatory test was done using ELISA, PCR and western blot Methods. A relatively high number of seropositive women fell in the age brackets of 30-34 which is 42.11% years while the least prevalence was between the ages of 20-24 years. Out of the four hundred (400) subjects screened thirty–eight seropositve which can be translated to a prevalence of 9.5% in Port Harcourt. The research work indicates that there is high HIV prevalence among pregnant women more especially during their sexual active age. The finding of this work is not at variance with work done in other parts of the world, based on the literature review. The research work indicates that there is HIV prevalence among pregnant women.