William Shakespeare's plays are renowned for their portrayal of complex and compelling female characters. In both his tragedies and comedies, Shakespeare challenges traditional gender roles and stereotypes, presenting women who are intelligent, independent, and assertive. This study examines the roles of women in Shakespeare's tragedies and comedies, focusing on the plays "Macbeth," "Hamlet," "Othello," "Twelfth Night," "Much Ado About Nothing," and "A Midsummer Night's Dream." The objective of this study is to analyze the portrayal of women in Shakespeare's tragedies and comedies, exploring how their characters challenge traditional gender roles and stereotypes. The study utilizes a qualitative approach, analyzing the text of the plays to identify key themes and character traits associated with the female characters. The analysis includes a comparison of the portrayal of women in the tragedies and comedies, highlighting differences and similarities in their roles and behaviors. The analysis reveals that women in Shakespeare's tragedies are often portrayed as victims of male ambition and jealousy, while women in his comedies are depicted as witty, intelligent, and independent. Overall, Shakespeare's female characters challenge traditional gender roles and stereotypes, presenting a more nuanced and empowering view of women. Women play crucial roles in Shakespeare's tragedies and comedies, challenging traditional gender roles and stereotypes. The study highlights the importance of considering the context of Shakespeare's time when analyzing his portrayal of women, as well as the enduring relevance of his female characters in modern society.

The objectives of this research are to analyze and find weaknesses in the current regulations for storing notarial deed minutes and to find a reconstruction of regulations on the legality of electronically storing minutes of notarial deeds based on the value of justice in a constructivism paradigm with a social legal research approach method to solve research problems by examining secondary data and primary data by finding legal realities experienced in the field as well as qualitative descriptive methods, namely where The data obtained is then arranged systematically so that a comprehensive picture will be obtained, where later the data will be presented descriptively. Research results show that the Weaknesses consist of (a) Legal structure where there are no communication and informatics experts which means electronic storage of certificate minutes cannot be implemented (b) Legal substance including unclear norms in UUJN Article 15 paragraph (3) UUJN, Unclear norms in UUJN no. 2 of 2014 Article 1 number 13. Weaknesses in proving Article 1868 of the Civil Code. (c) Legal Culture, namely the difficulty for senior notaries to understand new technology and tend to stick with old technology. Therefore, the reconstruction of Pancasila values in the electronic storage of deed minutes creates an electronic notary system because it can create a product that is more accurate, relevant, economical, trustworthy, faster, and more practical. Reconstruction of Law Number 2 of 2014 concerning Amendments to Law Number 30 of 2004 concerning the Position of Notary Article 1 number 7 so that the Minutes of Deed are the original Deed containing the signatures of the presenters, witnesses, and Notary, which are stored in paper form and/or in the form of an electronic document as part of the Notary Protocol. Article 16 paragraph (1) letter b becomes (1) In carrying out his office, a Notary is obliged to: b. make deeds in the form of deed minutes and/or deed e-minutes and save them as part of the Notary's protocol.

This research aims to analyze and find the weaknesses in the regulation of reasons for divorce in Islamic marriage law in Indonesia currently and to reconstruct the regulations for reasons for divorce in Islamic marriage law in Indonesia based on the value of justice using a constructivist paradigm with a socio-legal research approach method by examining secondary data and primary data by finding legal realities experienced in the field as well as a qualitative descriptive method, namely where the data obtained is then arranged systematically so that a comprehensive picture will be obtained, where later the data will be presented descriptively. The results of the research shows that the Weaknesses in the regulation of reasons for divorce in Islamic marriage law in Indonesia consist of: a). Legal Substance where Article 19 letter (f) Government Regulation Number 9 of 1975 and Article 116 letter (f) b). The Legal Structure consists of the weaknesses of the judge and the Weaknesses of the Mediator c). The legal culture where the husband's actions are super powerful, the increasing number of media broadcasting or presenting divorce issues, a cultural shift that exists where divorce is not considered taboo in society. Therefore, The reconstruction of the regulation of reasons for divorce in Islamic marriage law in Indonesia based on the value of justice consists of a value reconstruction where improvements are made to Article 19 letter (f) of Government Regulation Number 9 of 1975 concerning the Implementation of Law No. 1 of 1974 concerning Marriage and Article 116 letter (f) of the Compilation of Islamic Law so that continuous disputes as a reason for divorce can be in line with the objectives of Islamic sharia (maqashid syari'ah) being implemented. Reconstructing norms regarding Article 19 letter (f) Government Regulation Number 9 of 1975 concerning Implementation of Law No. 1 of 1974 concerning Marriage and Article 116 letter (f) Compilation of Islamic Law and Point C of Supreme Court Circular Letter Number 3 of 2023 by adding norms for divorce cases based on continuous disputes and quarrels can be granted if it is proven that the husband and wife have continuous disputes and quarrels which results in damage to religion, soul, reason, lineage and property which causes disharmony in the household.

The main cause of chronic HBsAg carriage is mother-to-child transmission. The aim of the study was to determine the epidemiological, clinical and biological aspects of mother-to-child transmission of the hepatitis B virus in newborns of HBsAg-positive mothers. Methodology: This was a descriptive cross-sectional study which took place from 1 March 2020 to 30 June 2021 at the CSREF in Commune V. Sampling was exhaustive, and all newborns whose mothers were carriers of hepatitis B were included in the study. Results: One hundred and twenty newborns out of 3197 referred from the maternity unit, representing a frequency of 3.7% of hepatitis B in pregnant women. Eighty newborns were included. The other 40 were not included because the mothers refused. Among the mothers, 11/80 tested positive for HBeAg and anti-HBs, with 2 positive results (18.18%). Twelve pregnant women had viral load tests, with two positive results (16.66%). Six of the 80 pregnant women had received tenofovir during pregnancy (7.5%), and all the newborns had negative HBsAg results at 4 months of age. Conclusion : Low realization of viral markers of hepatitis B and treatment during pregnancy.

Atypical giant parathyroid adenoma is a rare tumor with unusual histological features, an unusual presentation of primary hyperparathyroidism but more elevated laboratory findings and more severe clinical presentation due to larger tissue mass, and defined as weighing>3.5 g, leading to diagnostic and therapeutic challenges. Herein, we report a case of a 56-year-old woman who presented with a palpable neck mass, fatigue, persistent hypercalcemia, osteoporosis and asymptomatic renal stones, Ultrasound showed a left-sided solid nodule, and Sestamibi nuclear scan showed a giant parathyroid adenoma. The diagnosis of giant atypical parathyroid adenoma was confirmed after surgical excision size (3.5*1.5cm). We discuss the investigations, treatment, and outcome of this rare case and highlight the importance of long-term follow-up care.

In this study an attempt has been made to study the attitude of the higher secondary school teachers towards the implementation of sex education at higher secondary level in Murshidabad district of West Bengal, India. For this purpose, 380 higher secondary school teachers were randomly selected and attitude towards the implementation of sex education scale administered to them. To study the significance of difference between the various groups, ‘t’ test was applied by the researcher. The overall results indicate that the higher secondary school teachers (both urban and rural) possess highly favourable attitude towards the implementation of sex education. And there is no significance difference in the attitude of higher secondary school teacher towards the implementation of sex education in relation to their gender (i.e. male and female), locality (i.e. rural and urban) and stream (i.e., arts, science and commerce).

The issue of elderly care resulting from the aging population in East Asia has garnered significant attention, with a growing emphasis on disease prevention over treatment. The integration of health Qigong with traditional Chinese medicine and exercise offers long-term benefits for the physical form and function of middle-aged and elderly individuals. Due to its distinctive philosophy and aesthetic characteristics, health Qigong has gained prominence both domestically and internationally, serving as a medium for promoting health communication and enhancing population health levels. In an aging society, incorporating culture into the communication process of health Qigong along with narrative content is an effective approach to foster health communication. By integrating aesthetic principles into research, this study analyzes three dimensions: 1) physical health; 2) cultural aspects; 3) kung fu philosophy. Consequently, it proposes an aesthetic narrative strategy for health communication that encompasses embracing one's age, appreciating cultural perspectives, and valuing simplicity.

This paper analyses vibration of uniform flexible simply supported rectangular isotropic beam under large deformation with uniformly distributed mass elements. The method of equivalent pseudolinear systems was employed. The deformation of the beam was assumed to be large and the beam was also assumed to be inextensible. The expressions for elastic and nonlinear bending moments were determined. The numerical values of horizontal displacements of the movable support, and the equivalent lengths at various depth-to-breadth (aspect) ratios were determined. The corresponding equivalent pseudolinear systems for various nonlinear bending moment diagrams at various aspect ratios were determined. Consequently the concentrated loads yielding the equivalent pseudolinear systems were converted to point masses using the gravitational acceleration; and subsequently a unit load system was applied successively and independently at each mass point. The Vereshchagin’s method was applied to determine the displacements for canonical equations of motion. Non-trivial solution of the canonical equations at each aspect ratio was sought for the desired eigenvalues. The first mode frequencies at aspect ratios, β = 1.00 and β = 1.25 are complex eigenvalues. Also the natural frequencies exhibit hard-spring type with aspect ratios; and the fundamental frequencies for all the aspect ratios are at seventh mode. Conclusively, the dynamic stability of the flexible rectangular beam of 0.25m-breadth and 15m-undeformed length is not guaranteed when the aspect ratio is less than or equal to 1.25. It is also concluded that deepness of the flexible rectangular beam loaded with uniformly distributed mass elements influences the vibratory characteristics.

Background: The cephalic index and head circumference are important anthropometric parameters that can provide insights into the physical characteristics and growth patterns of populations. There is dearth of data on Cephalic Index and Head circumference of Igbo Children and Adolescents. Method: This study examined 725 Igbo children and adolescents aged 5 to 19 years in Enugu, South-eastern Nigeria, using a cross-sectional approach. Results: The majority of participants exhibited mesocephalic head shape (43.2%), with brachycephalic and dolichocephalic shapes observed in 32.7% and 14.2% of the population, respectively. Mean head circumference increased with age in both sexes. Cephalic indices in boys under 12 and girls under 15 were below 80 but increased above these ages. Changes in head shape, potentially towards brachycephalization, were noted as children grew. Significant correlations were found between head circumference and cephalic index with age, height, weight, and body mass index, suggesting their relevance in forensic and anthropological investigations. Conclusion: Our results indicate diversity in head shapes and sizes, with mesocephalic heads being most common. As age increases, head circumference also tends to increase, and changes in head shape towards brachycephalization was observed. These findings underscore the importance of understanding anthropometric variations in different populations and suggest avenues for further research, particularly longitudinal studies, to explore the factors influencing these patterns.

Background: This study aimed to assess the awareness of nurses who care for pediatric patients related with drug preparation and administration conducted in Gaffer Bin Auf children hospital. Methods: A cross-sectional study was conducted from November to December 2015, in Gaffer Bin Auf children hospital, largest pediatric hospital in Khartoum state. The total sample size was 92 participants. The self-administered questionnaire was constructed with a total of 26 questions. For data analysis, we performed nonprobability descriptive study design. Results: The results imply that Majority of respondents aged between 20-30 years (56.5%). Approximately half of the nurses held a bachelor’s degree (52.2%), while the remainder held a diploma (47.8%). A significant proportion of nurses (83.7%) reported no prior training in drug preparation and administration. Most nurses (46.7%) had 2-5 years of clinical experience, and 69.6% worked afternoon and night shifts. Regarding drug preparation and administration, varying levels of knowledge were observed among nurses. Notable percentages of nurses demonstrated awareness in areas such as double-checking during preparation (56.5%) and using distilled water or normal saline for non-contraindicated suspension drugs (56.5%), nurse answered can avoid a mistake during Preparation by prepare medication for one individual at a time with (90.2%), most of nurses have good level of knowledge regarding to drug preparation & administration practice with (65.6%). bachelor's degrees are more likely to demonstrate proficient drug preparation and administration practices compared to those with diplomas, with a significant difference of 94% (p=0.047, AOR: 0.6, 95% CI: 0.03, 1.1). This research indicating that bachelor's degree nurse graduates generally exhibit better educational preparedness for quality and safety. Additionally, participants working morning shifts are 3.4 times more likely to exhibit good drug preparation and administration practices compared to those on night shifts (p=0.011, AOR: 3.4, 95% CI: 1.3, 8.1), and 4.6 times more likely compared to those on afternoon shifts (p=0.015, AOR: 4.6, 95% CI: 1.8, 9.2). Participants with good knowledge of drug preparation and administration practices are 2.614 times more likely to exhibit proficiency compared to those with poor knowledge (p<0.001, AOR: 2.614, 95% CI: 1.78, 3.90). Conclusion: The study revealed significant insights into the demographic characteristics, educational backgrounds, and practices related to drug preparation and administration among nurses. Despite a substantial portion reporting no prior training, varying levels of knowledge were evident, with most nurses demonstrating awareness in key areas such as double-checking during preparation and using appropriate solutions for suspension drugs. While there are areas for improvement, the findings suggest a solid foundation of knowledge among nurses regarding medication safety, highlighting the importance of ongoing education and fostering a culture of continuous learning within healthcare ..............

Triple-negative breast cancer (estrogen receptor negative, progesterone receptor negative and HER2 negative) is a particularly high-risk breast cancer which does not receive specific therapy targeting these proteins. We report the case of a 23-year-old patient diagnosed with triple-negative breast cancer of the left breast with a family history of breast cancer and carrying a BRCA1 mutation. The classification of breast cancer based on genomic data is required to allow us to optimize therapies and improve the management of breast cancer patients.

Papillary thyroid carcinoma (PTC) is the commonest endocrine thyroid malignancy. The concurrent incidence of intrathyroidal parathyroid adenoma and papillary thyroid carcinoma is an infrequent finding. Surgical treatment via excision is the only definitive management approach. Here in we present a case report of intrathyroid parathyroid adenoma with incidental papillary micro carcinoma in a 36 year-old-female who initially presented with osteoporosis.

Microteaching is an innovative educational method that began to be applied almost fifty years ago in teachers’ education and training, with its application subsequently expanding to other professional environments. This paper focuses on the study of the role and application of microteaching and attempts to demonstrate its value and importance mainly concerning candidate and serving teachers’ education and training. This article initially presents the definition, the object, the stages, and the scientific foundation of the method under discussion. Then, general information is provided for the application of microteaching both in Greece and internationally. Finally, the value of microteaching, its importance, and its contribution, especially in teacher education and training, are analyzed and discussed.

Vitiligo is a chronic autoimmune disorder characterized by patches of skin losing pigment due to the destruction of melanocytes, the cells responsible for producing pigment. The condition can affect people of all ages and ethnicities, with symptoms including milky-white patches on the skin, premature graying of hair, and color loss in mucous membranes like the mouth or nose. Among the main causes of vitiligo are; Autoimmune Response: Vitiligo is primarily an autoimmune disease where the immune system mistakenly attacks melanocytes, leading to depigmentation. Factors like family history, genetic predisposition, and immune system disorders contribute to its development, Triggers: Events such as sunburn, emotional distress, or exposure to certain chemicals can trigger or exacerbate vitiligo. The treatment options are; Medications: Treatments include light therapy (phototherapy), oral medications like psoralen combined with UVA light (PUVA), and depigmentation therapy using monobenzone to match skin tones Surgery: Surgical options are available for some cases of vitiligo and Psychological Support: Counseling and mental health services can help individuals cope with the emotional impact of vitiligo, in conclusion, v is a multifaceted skin condition lacking a conclusive remedy, many types of vitiligo, but the most common one is Non-segmental Vitiligo (NSV), honmental and genetic are the most important causes of vitiligo. Important symptoms of vitiligo are; depigmented patches, hair discoloration, sensitivity to sunlight, treatment of vitiligo have many approach, among them are; topical Corticosteroids, phototherapy and Cosmetic Camouflage.

Critical thinking is part of the skills needed in science learning in the 21st century. However, the PISA test results show that the level of critical thinking abilities of students in Indonesia is still relatively low. This research was carried out as an effort to overcome this, by developing teaching materials on reaction kinetics based on tetrahedral representations with an ethnoscience approach to improve students' critical thinking skills. This research was carried out in development stages involving 5 expert and practitioner validators and 66 students. Data was collected using questionnaires, observation sheets and test instruments. The data analysis technique used is descriptive data analysis technique, namely by describing the validity, practicality and effectiveness of the teaching materials being developed. The results of this research show that the teaching materials developed are very valid with a validity score of 90.91% and very practical with a practicality score of 90.97%. These results indicate that the teaching materials developed are suitable for use in order to improve students' critical thinking abilities.