The aims of this research are: 1) to determine the material offense of possessing explosives (detonators) without a permit (study of decision Number 1676/Pid.Sus/2019/PN Mks); 2) to find out the judge's considerations in decision Number 1676/Pid.Sus/2019/PN Mks. This type of research is empirical legal research carried out to look for legal problems or issues and existing legal problems. The result of this legal research is to provide a prescription regarding what should be regarding the legal issue being raised. The results of this research are: 1) The material offense of possession of explosives or detonators without a permit (study decision Number 1676/Pid.Sus/2019/PN.Mks) is Article 1 paragraph (1) of the Emergency Law of the Republic of Indonesia Number 12 of 1951 Because this law is still in force, the public prosecutor used this provision to charge Risal Wali who was legally proven to have committed a criminal offense without a permit for possessing explosives. 2) The judge's considerations in handing down decision Number 1676/Pid.Sus/2019/PN.Mks against the Defendant of a crime without permission to possess explosives/detonators were: a) There was an indictment from the Public Prosecutor; b) Evidence-based on evidence; and c) There are aggravating and mitigating reasons. Judges at the Makassar District Court regarding the factors that form the basis of the judge's consideration in imposing a crime consist of a) the Criminal Code is the basis for the judge's consideration; b) The Defendant is the basis for the judge's consideration; c) Community demands are taken into consideration by the judge.

The synthesis and characterization of Schiff base-containing transition metal complexes have gained increasing importance due to their catalytic roles in various reactions and their biological activities. These metal complexes have become crucial in drug design, leading to a growing interest in metal-based drugs. The study aimed to synthesize copper metal complex with a new Schiff base ligand 4-[(3-hydroxybenzalidene)amino]antipyrine derived from 4-aminoantipyrine and 3-hydroxybenzaldehyde, as well as evaluate their antimicrobial activity against gram positive and gram-negative bacterial strains. The ligand and its copper complex were assessed for antimicrobial activity against gram-positive and gram-negative strains utilizing disc diffusion and broth dilution methods. Spectroscopic techniques (UV-Vis, FT-IR, XRD, and EDXRF), solubility tests, and elemental analysis were employed to investigate the ligand and copper complex. The ligand displayed high insolubility in various solvents but had limited solubility in chloroform and methyl chloride. The FTIR spectrum of the Schiff base reveals the presence of aromatic hydrocarbons, imine (C=N), hydroxyl (-OH), secondary amine (C-N), carbonyl (C=O), and vibrations associated with C-O and C-C bonds, reflecting its molecular structure. In the EDXRF analysis, a prominent peak at 7.80 keV corresponding to copper was detected, indicating that copper is the most abundant element found in the ligand. XRD analysis demonstrated distinct crystal structures for both the ligand and its copper complex. The UV-Vis spectra of the ligand exhibited an absorption peak at a UV lambda max of 220 nm, indicating a π→π* transition. In contrast, the absorption peaks observed in the copper complex indicated different transitions compared to the Schiff base. The MIC results indicated the copper complex's stronger antimicrobial activity than the Schiff base against tested bacteria. Molecular docking studies showed that the interaction energies of the synthesized compounds, particularly the ligand and copper complex, surpassed that of the well-known anti-diabetic drug, metformin.

Background: Hypertensive disorders during pregnancy, including gestational hypertension and preeclampsia, can lead to adverse outcomes for both the mother and the baby. Exploring the perinatal outcomes of pregnant women with hypertensive disorders is crucial for improving maternal and neonatal health. Aim of the study: This study aimed to assess the perinatal outcomes of pregnant women with hypertensive disorders. Methods: This cross-sectional study was conducted at the Department of Gynecology & Obstetrics, 250 Bed General Hospital, Meherpur, Bangladesh from January 2021 to December 2021. A total of 87 pregnant women with hypertensive disorders were enrolled in this study as the study subjects purposively. For data analysis, MS Office tools were used. Results: In this study, the majority of participants underwent cesarean delivery (55%), with 38% having a normal vaginal delivery, and 7% undergoing instrumental delivery. Maternal complications included HELLP (Hemolysis, elevated liver enzymes, and low platelets) syndrome in 18% of cases, abruption placenta in 8%, and pulmonary embolism in 6%. Normal perinatal outcomes were observed in 51% of cases, while 26% experienced preterm birth, 15% had low birth weight, 6% resulted in stillbirth, and 2% led to intrauterine fetal death (IUFD). Conclusion: By administering appropriate interventions, the incidence of cesarean delivery may be reduced in pregnant women with hypertensive disorders. Physicians are strongly encouraged to pay special attention to prevent HELLP (Hemolysis, elevated liver enzymes, and low platelets) syndrome in these cases.

The paper investigated the educational backgrounds of parents of elementary students in Osun state, Nigeria. It aimed to analyze the connection between parents' educational attainment and the educational performance of elementary pupils in the subject of Social Studies. Additionally, the work explored the relationship between family state and the educational achievement of elementary pupils. The investigation employed a descriptive correlational survey research design. The target study comprised pupils aged 5-8 years old and their parents residing in Osun State. The sample population consisted of 300 students and 300 parents, selected through a multistage selection technique. From every selected school, twenty (20) children were chosen using a simple random selection procedure, and all parents of the chosen pupils were purposefully employed for the study, comprising 300 pupils and 300 parents who comprised the study's sample. The two research instruments were “Questionnaire on Family Structure and Parents' Educational Levels” (QFSPEL) and “Pupils' Previous Terms Results in Social Studies” (PPTRSS). The data collected were analyzed statistically using frequency, percentage, and “Pearson Product Moment Correlation (PPMC) methods” The research findings shows that the degree of lower primary school children' family structure is very high in Osun State, at 78.5%. The findings found that the level of education of lower primary school children’s parents was high in Osun State, at 58.1% in the study results, a significant and positive correlation (r = 0.885; p < 0.05) between parents' educational levels and the academic achievement of lower primary school students in Social Studies within the study area. On the other hand, the study did not find a significant correlation between family settings and the educational abilities of lower elementary children of study area in Social Studies (r = 1.978; p > 0.05).

The research is geared towards investigation on one hand the extent to which Hausa is found on the internet, and utilizing the internet for documenting Hausa materials on the other. The most active internet search engines (i.e. AOL, Ask, Baidu, Bing, DuckDuckGo, Google, Internet Archive, WolframAlpha, Yandex. and Yahoo) were utilized to determine the number of existing and functioning Hausa websites. The activities and contents of the websites were studied to ascertain if they help matters by providing the needed materials for the ‘Hausa academic world’. The areas and forms of weaknesses of the sites were studied accordingly. It has been observed that the Hausa websites are dominated by several challenges ranging from socio-political to environmental. Finally, suggestions are offered as panaceas for the observed problems, one of which is the need for a collaborative effort between departments and centers for the studies in the Hausa language and the enthusiastic Hausa bloggers for the attainment of common documentation and improvement goals.

Diabetes is a common chronic metabolic disease that has attracted a lot of attention in the dental community because of its possible effects on peri-implant therapy. Dental implant procedures have grown in popularity as a means of replacing lost teeth. This systematic review aims to investigate the ways in which diabetes impacts different peri-implant therapy aspects. Up until February 2023, electronic databases such as PubMed, MEDLINE, and Embase were thoroughly searched. Eleven studies in total that complied with the inclusion criteria were included in the final analysis. These studies used both prospective and retrospective designs to investigate the impact of diabetes on implant outcomes. An overview of the impact of diabetes on the outcomes of peri-implant therapy, such as implant success, survival, and tissue health around the implants, is given in this abstract. Numerous studies repeatedly show that diabetes adversely affects these crucial facets of implant therapy. Diabetes affects soft tissue health around dental implants, lowers implant survival rates, and increases the risk of peri-implantitis.

Reproductive process cannot be complete without hormone and if these hormones are not in the right proportion, then reproductive process could fail. Hormones are chemical substances produced by the endocrine gland and its physiological action is exerted on a target organ different from the secretion’s site. The aim is this study is to evaluate Effect of aqueous leave extract of D. alba ness (Thorn Apple) on gonadotropic hormones (FSH, LH) and prolactin following administration of MSG and clomid citrate in male wistar rats. The study involves 35 male wistar rats weighing between 130g to 160g. The animals were randomly selected into 7 with five animals per group. Each group received the following: group 1 10mls/kg of distil water, group 2 low dose of extract (1000mg/kg), group 3 high dose of extract(2000mg/kg), group 4 MSG 800mg/kg, group 5 clomid 50mg/kg, group 6 MSG + high dose of extract and group 7 clomid+ high dose of extract. Administration of extract was done through oral gavage for 21 days, thereafter, the animals were sacrificed on the 22nd day, and blood samples were collected for hormonal analysis. The results showed significant increase in serum levels of FSH and LH in the MSG group and decreased in FHS levels in all others treated groups when compared with control. The serum levels of FSH and LH rises when extract was co-administered with MSG. The serum levels of LH slightly increased when extract was co-administered with clomid serum levels of FSH do not increased when extract was co-administered with clomid. The statistical analysis was carried out using Statistical Package for Social Science (SPSS) version 23.

Background- The writers used a custom-built electronic utmost agreement to examine endodontic analytical and management consequence measurements in patients with and without diabetes. Methods- The medical histories and endodontic management statistics for nonsurgical endodontic patients treated in predoctoral and postgraduate specialty clinics were entered into an electronic record system. A entire of 5,134 cases (including 284 cases in patients with diabetes) were treated, and 150 cases (including 63 cases in patients with diabetes) had follow-up data two years or additional postoperatively. The writers applied and multivariate evaluates to control significant issues touching endodontic analysis and treatment. Results- Patients with diabetes had enlarged periodontal infection of teeth with endodontic connection associated with patients who did not have diabetes. There was a movement near enlarged suggestive peri-radicular illness in patients with diabetes who conventional insulin, as well as flare ups in all patients with diabetes. Two years or longer post-operatively, 58 percent of cases surveyed were effective. Older age, the absence of preoperative lesions, the presence of permanent restorations and longer postoperative evaluation phases all were supplementary with an effective outcome. A multivariate examination displayed that in cases with preoperative peri-radicular lesions, a history of diabetes was supplementary with a meaningfully complete successful outcome. Conclusions- Patients with diabetes have enlarged periodontal disease in teeth involved endodontically and have a reduced likelihood of success of endodontic treatment in cases with preoperative peri-radicular lesions. Clinical Implications- Patients with diabetes who are preserved endodonticaly should be evaluated carefully and be preserved with operative antimicrobial root canal regimens, mainly in cases with preoperative lesions.

Phytomedicine has become popular among and majority of women depends on herbal medicine when seeking healthcare. Several women opted for herbal medicine when looking for fertility and most the women that hormonal imbalance depends on herbal medicine for correction. Hormones is substance that must be required and must be in the right values for reproduction to occur. The aim is this study is to ascertain the Effect of aqueous leave extract of D. alba ness (Thorn Apple) on gonadotropic hormones (FSH, LH) Treated with monosodium glutamate (MSG) and clomiphene citrate in female wistar rats. The animals were randomly selected into 7 with five animals per group. Each group received the following: group 1 10mls/kg of distil water, group 2 low dose of extract (1000mg/kg), group 3 high dose of extract(2000mg/kg), group 4 MSG 800mg/kg, group 5 clomid 50mg/kg, group 6 MSG + high dose of extract and group 7 clomid+ high dose of extract. Administration of extract was done for 21 days, and on the 22nd day, the animals were sacrificed and blood samples were collected for hormonal analysis. The results revealed significant decreased in the serum levels of follicle stimulating hormones (FSH) in all the treatment groups (extract 1000mg/kg, extract 2000mg/kg, MSG 800mg/kg, MSG 800mg/kg + extract 2000mg/kg, and clomid 50mg/kg + extract 2000mg/kg) when compared with control and significant increase in serum levels FSH in clomid 50mg/kg treated group. Luteinizing hormone (LH) serum levels significantly decreased in all the treatment groups when compared with the control group. LH levels in the clomid group significantly increased when compared with other treatment groups. The statistical analysis was carried out using Statistical Package for Social Science (SPSS) version 23.

Manufacturing is an industrial component that is widely regarded as the cornerstone of both social and economic development. This study investigates the drivers of manufacturing export performance in Nigeria for the period 1981-2019. Given the existence of endogeneity problem in the model, the study under a dynamic time series estimation employed GMM estimator. Manufacturing exports performance was measured using growth rate of manufactured exports, percentage of manufacturing export in GDP and manufactured export as percentage of total export. The results show that improvement in the degree of trade openness, increasing manufacturing value added, access to financial services, relative prices and increasing investment level through FDI were found to be the determinant factors that have tendency to enhance manufacturing exports performance in Nigeria. Based on these findings, policy implications include providing adequate financing and increasing credit allocation to the manufacturing sector, as well as implementing policies aimed at promoting access to financial services in order to ensure efficient distribution to the preferred sector. The Nigerian government should implement trade barriers-removal policies while also promoting policies that lead to the country's exceptional advancement. Other policy recommendations derived from the empirical findings are thoroughly discussed in the concluding part of the paper.

Introduction: The prevalence of glaucoma and cataracts has been rising. The crowded anterior segment architecture that results in appositional contact between the trabecular meshwork and the peripheral iris is the cause of primary angle closure. A technique to control intraocular pressure and deepen the anterior chamber is lens extraction. Objectives: To evaluate intraocular pressure changes in narrow angle eyes following phacoemulsification with intraocular lens implantation. Methodology: The study was carried out between March 2015 and August 2017 at Department of Ophthalmology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh on patients diagnosed with narrow-angle who also developed cataract. A narrow angle was defined as an anterior chamber angle grading of 2 or less on Shaffer grading in three or more quadrants. In accordance with the inclusion and exclusion criteria, a sample from the study population was drawn using the purposive type sampling technique. Participants in this prospective trial had foldable lens implantation after phacoemulsification surgery. Goldman applanation tonometry was done prior to surgery as well as on the tenth and thirtieth postoperative day. Results: The study included thirty eyes from 29 individuals, with a male to female ratio of 1:1 and an overall mean age of 62.03±8.95 years. Preoperative IOP was 13.66±1.69 mm Hg on average. The mean IOP at the 10th and 30th POD was 11.83±2.21 mm Hg and 11.00±2.07 mm Hg, respectively. At the final follow-up, the mean IOP drop was 2.66 mm Hg (p<0.05). Conclusion: In individuals with narrow angles, phacoemulsification combined with posterior chamber intraocular lens implantation can lower intraocular pressure. These results support the notion that phacoemulsification combined with foldable IOL implantation is a useful technique for reducing intraocular pressure.

The transformation of terrorism from Al-Qaeda to the Islamic State (IS) has created new security challenges. This article examines the threats posed by these two groups by discussing their ideologies, structures and capabilities. Unlike local terrorist groups like the Afghan Taliban, the Islamic State and Al-Qaeda pose a global threat. The work looked at the origin of Al- Qaeda which cannot be separated from the soviet invasion of Afghanistan in 1979, and the objective of Al- Qaeda which main purpose is unifying and leading the jihad movement and providing its purpose and direction. The organization of Al- Qaeda was also discuss in this work, which is divided into four levels, which include, core Al- Qaeda, affiliated groups, allied groups and motivated persons and network. This work also assessed the impact of Al- Qaeda in global security, where some scholars argued that the group is not viable enough to pose global threat while others argued against it. On the other hand this work examined the origin of IS which started as a result of U.S military intervention in Iraq in 2003. It also examines resource base of IS and its objectives which is the destruction of the asymmetry status- quo existing for a long between Muslim countries and the Western allies. The impact and threat assessment of Al- Qaeda and IS on global security which we found out is that IS initially was fighting the near enemy in Iraqi and Syrian regimes, but latter changed its strategy by equally focusing on the “far enemy” as well, and manifested in its high profile attacks in Europe and other places beyond the Middle East. Lastly the researcher look at the differences between Al- Qaeda and IS in terms of their structure, brutality, popularity, conceptual difference etc. At the end, this paper recommends that a comprehensive global strategy is required to eradicate this growing menace of organized terrorism.

Children's growth, health, and development depend on proper nutrition in infancy and early childhood. Worldwide, nursing is advantageous for both mother and child since breast milk is the best source of baby nourishment. This study examined mothers' knowledge and attitude about exclusive breast feeding’s nutritional benefits. A cross-sectional survey of 384 mothers was conducted in rural Igabi LGA. The data was acquired using structured questionnaires. SPSS 21 was used to enter and evaluate data. Chi-square determined categorical data associations. Statistical significance was set at p<0.05. By knowledge score, 13.80% of mothers had adequate knowledge, 51.04% intermediate, and 35.15% deficient. Attitude score: 63.80% of mothers were positive. Most mothers (52.5%) reported breast problems as major issues. A local language campaign to educate women about the nutritional benefits of exclusive breastfeeding and renewing the Baby-Friendly Hospital Policy can reduce child mortality, according to the study.

Doxorubicin-induced cardiotoxicity is the leading cause of morbidity and mortality among cancer survivors. The present study aimed to investigate the ameliorative effect of 5, 7-dihydroxyflavone (chrysin) against doxorubicin-induced cardiotoxicity in Wistar rats. Thirty-five adult male Wistar albino rats were randomly allocated into seven groups (n = 5 each) which consisted of normal control (group 1) receiving phosphate buffer saline (0.4 ml), positive control (Group 2) received 2mg\kg of doxorubicin (DOX) through an intraperitoneal route once weekly for 21 days, chrysin low dose and chrysin high dose (Group 3 and 4) received oral administration of chrysin 50&100mg/kg for 21 days, chrysin low dose and DOX, chrysin medium dose and DOX and chrysin high dose and DOX(group 5, 6, and 7) received 2mg/kg of DOX once weekly with 50, 100 and 150mg/kg of chrysin for 21 days. Significant elevations in cardiac troponin I (cTnI) and histological lesions, which corresponded with oxidative stress, inflammation, apoptotic indicators, and cardiotoxicity when compared to controls, were indicative of DOX-induced cardiotoxicity. Malondialdehyde (MDA), a sign of oxidative stress, SOD, CPK (creatinine phosphokinase), TBARS (thiobarbituric acid reactive substance), and CAT (catalase) were also elevated in the DOX group. The DOX group also had increased levels of cardiac inflammatory markers, including as interleukin-1 (IL-1), interleukin-6 (IL-6), and the apoptotic marker caspase-3. 5, 7-dihydroxyflavone (chrysin) significantly mitigated, but did not entirely reverse, the cardiotoxicity caused by DOX by reducing the histopathological scores of cardiomyopathies and lowering cTnI in comparison to the DOX group. Additionally, chrysin reduced MDA to substantially similar levels as the control. Following chrysin administration, significant decreases in IL-1, IL-6, and caspase-3 were also seen in comparison to the DOX-only group. All things considered, these findings point to chrysin's protective action against DOX-induced cardiotoxicity, which may have been rendered possible by oxidative stress, inflammatory, and apoptotic suppression.

Since 2018, are still disparities in the research results on items, prices, locations, promotions, people, processes, and physical evidence associated with customer loyalty based on the marketing mix and customer or patient loyalty. This study’s compares the theory and practice concerning the effect of marketing mix to outpatients’ loyalty. Hajj Hospital is currently experiencing a drop in the number of patients though numerous promotional efforts have been made, particularly during the COVID-19 pandemic. It is anticipated that the marketing mix will enhance consumer views of a product’s quality, as measured by consumers’ evaluations of the product. If the consumer perceives that the hospital provides high-quality services, the hospital’s image will be positive; this condition might boost customer or patient satisfaction. This study aims to determine which element of the marketing mix has the most significant impact on patient loyalty at Hajj Hospital. This study used a quantitative cross-sectional design approach, with 100 outpatient samples, and was analysed using SPSS. It was discovered that additional studies incorporated planning, control, monitoring, and evaluation into the marketing mix, utilising longitudinal studies or interventions for healthcare professionals that provide services to patients.