ORIGINAL RESEARCH ARTICLE | July 1, 2026
Detection of Interleukin-27 and Matrix Metalloproteinase-9 Levels in Patients Serum of Helicobacter pylori
Khalil Ismail Abid Mohammed, Wifaq M. Ali, Ameen Abdul Hasan AL-Alwany, Suha A. AL-Fakhar, Jinan M. Mousa
Page no 337-342 |
https://doi.org/10.36348/sjls.2026.v11i07.001
The study was carried out to detection of H.pylori in [200] patients who attended two teaching hospitals in Baghdad. The diagnosis done by Immunochromatography methods. Stools and blood Samples was taken from each patient as well as other [30] healthy control matching in their age. The study included detection the Levels of Interleukin-27 and Matrix Metalloproteinase-9in sera of the patients and the control. The result indicated presence of H pylori antigen in 115 cases 69 cases of males and 46 of females, Also, the results indicated increasing levels of Interleukin-27 and Matrix Metalloproteinase-9 in patients’ sera in comparison with healthy control.
REVIEW ARTICLE | July 3, 2026
Ichthyophthiriasis (Ich / White Spot Disease) in Aquaculture Systems: Biology, Epidemiology, Pathogenesis, Economic Impacts and Control Strategies
Usman Naveed, Rimsha Latif, Rashid Hussain Dahar, Nasim Yasin, Zareena Khadim, Gumza Mushtaq, Mahroz Fatima Zaidi, Alishba Fatima, Muhammad Usama
Page no 343-354 |
https://doi.org/10.36348/sjls.2026.v11i07.002
One of the most important parasitic diseases in freshwater fish farming due to its clinical and economic importance, ichthyophthiriasis results from I. multifiliis (a ciliate obligate parasite) infection, also known as "white spot disease" or simply "Ich." This literature review is aimed at compiling the existing knowledge about the taxonomical position, biological features, and three-stage life cycle (consisting of the theront, trophont, and tomont) of the parasite under the influence of various environmental parameters such as temperature, salinity, and pH. In addition, the epidemiological features of the infection (host specificity, susceptibility factors, transmission methods, and seasonal prevalence) as well as host-parasite relationships (mechanisms of parasite entry, i-antigen-induced immune evasion, and host response) will be considered. Clinical features and histopathological changes for various cultured species are reviewed along with the diagnosis, which includes both traditional methods as well as molecular diagnostics like qPCR and ddPCR. It is emphasized that the disease creates significant financial loss, costing more than USD 1 billion annually on a worldwide basis. The effect of the disease is significant in aquacultures from Europe, China, and North America. Prevention and management of this disease include chemical treatment, salt treatment, biological control, immunostimulants, vaccine, and biosecurity. There is no method available which gives total protection. Latest innovations in the fields of genomics, transcriptomics, novel treatment methods and DNA vaccines are also mentioned. The conclusion made by the authors is that sustainable management of I. multifiliis calls for an integration of various measures such as decreased use of chemicals, increased biosecurity, biological control, genetic resistance and precision aquaculture, with vaccine efficacy, drug resistance and climate change adaptation highlighted as key research areas.
ORIGINAL RESEARCH ARTICLE | July 9, 2026
Evaluation of Agro-Industrial Tuber Peel Waste as an Alternative Energy Source in Livestock Diets: Implications for Nutritional Value, Caloric Density and Mineral Enrichment
Lawrence Olusegun Ajala, Maruf Olaide Yekeen
Page no 355-363 |
https://doi.org/10.36348/sjls.2026.v11i07.003
This study investigated the nutritional, energetic, and mineralogical implications of replacing conventional maize with underutilized agro-industrial by-products in livestock rations. A 100% maize control diet (MFF) was evaluated against three experimental diets where maize was replaced at a 50% inclusion level with Irish potato peel meal (MPF), yam peel meal (MYF), or cassava peel meal (MCF). The partial substitution preserved total organic matter density across all formulations (>90%). However, the higher concentration of structural non-starch polysaccharides inherent to root and tuber epicarps significantly reduced carbohydrate and caloric delivery (p < 0.05). Nitrogen-free extract (NFE) decreased from 47.42% (control) to 38.92% (MYF), 38.05% (MCF), and 35.47% (MPF). The reduction in digestible carbohydrates led to a decrease in calculated metabolizable energy (ME) profiles, which fell from 10.43 MJ/kg (MFF) to 9.62 MJ/kg (MYF), 9.50 MJ/kg (MPF), and 8.72 MJ/kg (MCF) due to the dilution of physical fiber. Conversely, the incorporation of tuber wastes resulted in a substantial natural increase in the concentration of essential minerals. Potassium accumulated significantly in MPF (0.97%) and MYF (0.53%), while calcium surged from 28.47% (control) to peaks of 68.67% (MPF) and 65.63% (MYF). Magnesium uniformly exceeded 81% across all test groups, alongside prominent accumulations of iron and zinc. However, phosphorus was significantly depressed in the cassava peel group (MCF: 9.37%), altering optimal dietary Ca/P ratios. Ultimately, replacing 50% of maize with root crop by-products offers a viable strategy for maintaining organic matter stability and enhancing mineral content, as long as targeted micronutrient balancing is applied for sustainable feed production.
REVIEW ARTICLE | July 25, 2026
Micro and Nanoplastics in Biological Systems: A One Health Review of Environmental Toxicity, Microbial Dysbiosis, and Human Health Risks
Mudassar Akbar, Abuzar Mehdi Khan, Bismma Shahid, Muhammad Akash Khalid, Muhammad Irfan, Shumail Shamsher, Safia Abdul Ghafoor, Rohma Tahir, Ammara Khalid,Rashid Rabani
Page no 364-408 |
https://doi.org/10.36348/sjls.2026.v11i07.004
Micro- and nanoplastics have emerged as biologically active contaminants that connect environmental pollution with ecosystem dysfunction, microbial imbalance, animal toxicity, and human health uncertainty. This One Health review critically synthesizes current evidence on the sources, physicochemical characteristics, environmental fate, biological toxicity, microbial interactions, and medical relevance of micro- and nanoplastics in biological systems. These particles originate from primary manufactured materials and secondary fragmentation of plastic waste, synthetic textiles, agricultural plastics, tyre wear, packaging, wastewater, and atmospheric deposition. Their toxicity is strongly influenced by particle size, shape, polymer type, surface chemistry, aging, biofilm formation, and contaminant adsorption. In plants and ecosystems, micro- and nanoplastics can impair seed germination, root architecture, photosynthesis, nutrient cycling, soil microbial activity, crop productivity, and ecological stability. Animal studies further demonstrate oxidative stress, inflammation, neurotoxicity, reproductive injury, developmental disruption, gut damage, and metabolic disturbance, although many experiments still rely on high doses and pristine laboratory particles. Microplastics also create plastisphere biofilms that alter soil, aquatic, and gut microbiomes and may facilitate pathogen survival and antimicrobial resistance gene dissemination. Human exposure occurs through food, drinking water, air, dust, and consumer products, with increasing detection in blood, lung, placenta, breast milk, vascular tissues, and other biological samples. However, causal links with chronic disease remain uncertain due to limitations in detection, dose standardization, contamination control, and long-term epidemiological evidence. Overall, micro- and nanoplastics represent an emerging cross-sectoral biological threat requiring standardized monitoring, realistic toxicology, biosensor development, biotechnology-based remediation, safer material design, and integrated One Health risk assessment.
REVIEW ARTICLE | July 25, 2026
Medicinal Plants in Veterinary and Wildlife Health: Therapeutic Applications, Disease Management and Conservation Perspectives
Iram Hassan, Usman Naveed, Bushra Mumtaz, Muhammad Athar Tahir, Nida Zulafiqar, Maheen Sattar, Saira, Rimsha Latif, Atifa Farooq, Asma Anwar, Sana Riaz, Sana Andleeb
Page no 409-428 |
https://doi.org/10.36348/sjls.2026.v11i07.005
Antimicrobial resistance, strict regulations on the use of antibiotics in livestock and consumer preference for sustainable livestock products have once again drawn attention to the role of medicinal plants as complementary or alternate means of treatment in the veterinary field. This review consolidates evidence from 151 peer-reviewed articles in order to critically analyze the possibilities in the use of phytomedicines in the context of One Health through an analysis of its therapeutic possibilities, disease management roles and even the conservation aspect. The history and ethnobotany behind the use of plants in animal therapy is explored, along with the pharmacology behind the major bioactive principles alkaloids, flavonoids, terpenoids, essential oils and tannins discussing their mode of action that include cell membrane disruption, efflux-pump inhibitors, quorum-sensing inhibitors and immune modulation. Specific examples exist from studies involving species across livestock, companion and aquatic animals as well as captive and free-ranging wildlife that show antimicrobial, antiparasitic anti-inflammatory and wound healing properties, among others, with multi-target effects suggesting a possible approach for minimizing resistance development. The review highlights the trade-offs associated with the exploitation of botanical resources, focusing on conservation practices through cultivation efforts and community management, as well as current barriers to the development of plant medicine, which include lack of standardization, pharmacokinetic information, clinical studies and regulation. The review highlights that for moving forward from using veterinary phytotherapeutics in an empirical way to applying them scientifically, there is a need for concerted efforts toward conducting proper clinical trials, pharmacology research on animals, toxicity testing and regulation of the use of medicinal plants.