Magnesium supplements have been effective for modulating process of bile resistance, decrease oxidative stress and systemic inflammation. Current study was designed to functionally evaluate the MgO nanoparticle supplementation in an acute liver injury rat model. The animals were randomly divided into five groups. All groups were administrated with CCl4 to induce hepatic injury except of negative control group which received only vehicle. CCl4 administration is followed by MgO nanoparticles in the concentration of 150 and 300 mg/kg in low dose and high dose treated group respectively except of standard control group. After 21 days of treatment, the animals were sacrificed to collect blood and liver samples. Serum levels of bilirubin, AST, ALT and ALP were determined. Liver sample was also subjected to RNA isolation by Trizol method followed by the cDNA synthesis and Real Time PCR. In addition, lipid profile was also assessed. The data obtained was analyzed by one way analysis of variance (ANOVA). The results showed that levels of bilirubin, AST, ALT and ALP were significantly elevated in positive control group while MgO treated groups, somehow, had normal ranges of these enzymes. Furthermore, the qPCR results showed that the expression of Farnesoid X receptor (FXR), transcriptional regulator of the bile salt export pump (BSEP) and sodium taurocholate cotransporting polypeptide (NTCP), is reduced in positive control group, while nanoparticles treated groups had normal expression of these genes. In conclusion, our data showed that MgO nanoparticles possess hepatoprotective activity against hepatic injury.

Most of the molecular targets are genes involved in carbohydrate and sugar metabolism. The jasmonic acid signaling regulation controls a range of plant developmental processes and responses to biotic and abiotic stressors; this regulation most likely involves the photosynthetic apparatus. Proteases and peptidases that are specialized to certain compartments, their number, location, and turnover, protein interactors, and posttranslational modifications (PTMs) including phosphorylation, ubiquitination, nitrosylation, and carbonylation are among these activities. The adding pure natural components and plant extracts to food may help prevent botulism. Furthermore, given the lack of apparent pharmacological treatment, whole foods high in polyphenols and the bioactive substances contain have to be assessed for potential medical benefits. The food chain is seriously endangered by fusarium species and other fungal species that infect food, particularly grain. Mycotoxins' harmful effects on people are limited by the highest amounts that are allowed in food. Several nations have placed restrictions on the number of mycotoxins that can be found in food items.

The production of discrete guard cells without plasmodesmata, in addition to its highly specialised division and differentiation processes, makes the stomate an intriguing model for developmental biology. Most comparisons of the leaf nutritional properties of different plant forms are focused on the species scale or local scale. Understanding the intercellular communication, asymmetric cell division, and stomatal state transitions that underlie stomatal development in Arabidopsis thaliana. Pathogens affect animal populations, but population status, size, and density affect the rate and effectiveness of disease transmission and dissemination. There is an instantaneous effect of lessening the impact effect of precipitation by direct interception that slows the outflow because of the presence of trees, bushes, and lawn areas. Drought stress and pathogen infection can interact in both antagonistic and additive ways. Given how often drought stress occurs and how many plant diseases have been reported to be affected by it, this combination of stresses may be considered one of the most important combinations affecting crop yields. Physical stressors such as excessive moisture content preventing oxygen from diffusing to the root tip, hypoxia resulting from insufficient water availability, a negative matric potential, compaction, or soil drying can all limit the amount of root elongation.

Farm animal growth boosters, which are non-essential chemicals, have long been used by veterinarians and animal producers as feed additives or implants. These substances, which have anabolic action and enhance animal performance in many meat-exporting nations, include beta-agonists, anabolic hormones, and bovine somatotropin. Additionally, as the animal's nutritional status influences the availability of nutrients needed for the advancement of development and growth, the development of multiple and individual organs depends on it. Since the sources and accessibility of nutrients vary depending on the animal's developmental stage, changes in the animal's nutritional status are normal. Furthermore, obstacles from the external environment also drastically alter extrinsic nutritional conditions. Despite tremendous advances in animal science and related technologies, there are still a lot of unanswered questions about how hormones impact the welfare and productivity of food animals as well as the public's perception of their usage. Bridging these gaps through translational and transformational research progress both basic and applied animal science, with the goal of feeding an expanding population.

Wheat is one of the most important crop. Which is cultivated in whole world. It belongs to Poaceae family. An experiment was performed to check the effect of foliar application of benzoic acid on growth and production of wheat. This experiment was conducted according to complete randomized design. Three treatments of benzoic acid (100 ml/L, 200 ml/L and 400 ml/L) were used. Data was recorded for plant height, number of tillers/m2, flag leaf area, spike length, number of grains/spike and plant dry weight/m2. Then data was analyzed by ANOVA and mean values of each treatment were compared by using Fisher’s LSD. The results showed that foliar use of benzoic acid at 200 ml/L provided the best results for all traits (number of tillers/m2, flag leaf area, spike length, number of grains/spike and plant dry weight/m2) except plant height. Foliar application of benzoic acid at 200 ml/L greatly enhance the growth and yield in wheat. This was because of increase in auxin production or increase in cell division. While height was the only trait which was gradually decreased with the increase of benzoic acid level.

Snakebites are a serious public health problem in many regions of the world, particularly in rural areas lacking medical facilities. The World Health Organization (WHO) estimates that 81,000–138,000 people die each year from snakebites worldwide. Venomous snakebite and its effects are a source of fear for people living in southern Nepal. As a result, people have developed a negative attitude towards snakes, which can lead to human-snake conflicts that result in killing of snakes. About 48 People from different walks of life which includes farmers, teachers, businessmen, students and others were interviewed regarding their perception about snakes. The study reveals that 46/ respondents feared from snakes, 33/ respondents dislike snakes and 25/ like to kill all the snakes particularly venomous snakes.

The indiscriminate use of pesticides in agriculture has led to the contamination of aquatic ecosystems, adversely affecting non-target organisms such as freshwater fish. This study investigates the behavioral responses of the freshwater fish Channa punctatus to sub-lethal concentrations of the synthetic pyrethroid pesticide, fenvalerate. The results reveal significant alterations in swimming behavior, respiratory patterns, feeding activity, and overall responsiveness, indicating neurotoxic and physiological stress. These behavioral changes may impair the survival and ecological fitness of the species, emphasizing the need for stringent regulation of pesticide usage.