This article aimed to examine the relational implications of Computer-Assisted Language Learning (CALL) for the didactic triangle. This examination revealed that the introduction of computer has some impacts on the relations (Pedagogical, Curricular, and Didactic) existing in the didactic triangle which need to be addressed with special care: The indispensable nature of the teacher‟s roles is undermined, for the learner does not necessarily expect his intervention in order to progress in the learning process ; CALL imposes new constraints on the teacher who has to make additional effort in terms of professional skills and research in order to transform and adapt the content offered by technological tool to classroom realities; classroom realities (environmental, linguistic, experiential, representational, intellectual, etc.) might inhibit the learner‟s creative and language potentialities. To improve the implementation of CALL, I suggested a more structured didactic framework which would allow the language teacher to take advantage of this major asset in order to enhance the chances to achieve more dynamic participation of the learner in his own training.

This paper discusses whether home language has any effect on the teachers‟ views on code-switching use in the classroom. The paper is based on a quantitative study conducted at four senior secondary schools in the north-eastern Botswana whose teachers and learners had diverse home languages. Their views were solicited about the use of CS in the classroom and its effect on teaching and learning; and the results were analysed quantitatively. The results from the study showed that the teachers, irrespective of home language, code-switched in the classroom yet the country‟s Language in Education Policy (LiEP) states that English is the sole official Language of Instruction (LoI) from the second year of primary school and throughout the entire education system. However, teachers whose home language is Setswana codeswitch more than others. The paper calls for the appreciation of the existence of code-switching in the classrooms of the said senior secondary schools, and that ways of utilizing it should be explored bearing in mind that language diversity exists in the school environment.

Molecular and pharmacokinetic properties prediction is important determinant in the current drug development process. In this study, molecular and pharmacokinetic properties of phenoxy acids and their derivatives are theoretically predicted using in silico tools to determine how synthetic modifications such as branching, amidation, esterification, heterocyclic groups, and hydrazide group change the structural and pharmacokinetic properties with respect to the parent phenoxy acid. From the results it was observed that phenoxy acid possess good central nervous system (CNS) permeability compared to the acid derivatives. It could also be further predicted that conversion of phenoxy acid to functional derivatives leads to molecules with good pharmacokinetic profile. Based upon these theoretical predictions, it can be concluded that various chemical modifications of phenoxy acid moiety furnish promising derivatives with good pharmacokinetic profile and oral bioavailability.

Abstract: The subscription of Nigeria to MDGs and the attendant efforts of providing qualitative universal basic education by governments made international interventions in the sector visible in all parts of Nigeria. Such intervention is usually technical that tends to provide stakeholders, especially teachers, with internationally tested models that will boost their service delivery and bring improved output from teaching and learning activities. Jolly Phonics is one of such models that aim at teaching reading and writing to pupils at Primary 1&2 with letter sounds that are introduced through child centred strategies of songs, stories and 'actions'. Using Jolly Phonics Project of Zamfara State Universal Basic Education as a reference point, this paper features the critical role of home academics in adapting the model to the local linguistic and cultural environment of the host state.

The present study was undertaken to investigate the phytochemical constituents of two Nigerian grown kolanut and their antimicrobial properties. Extract of the seed of Cola nitida and Cola acuminata were used to determine the phytochemical constituent of aqueous and methanol nut extract and their solubility in the two solvents. Aqueous and methanol used reveals the solubility of these exrtacts in different solvent and the presence of secondary metabolites in the kola nut. Qualitative screening of the extracts of C. acuminata and C. nitida for phytochemicals revealed the presence of alkaloid, saponins, tannins, flavonoids, glycoside, steroid, saponins glycoside, cardiac glycoside and the absence of anthraquinones in all the extracts. Quantitative analysis shows that the methanolic extracts C. acuminata and C. nitida have the highest percentage of Saponins: (>10%) than the aqueous extract of the preparations. The disc method was used to determine the inhibitory effect of kolanut on the test microorganisms. Sensitivity patterns of zones of inhibition exhibited by the crude methanol and aqueous extract of Cola nitida and Cola acuminata shows that the nut possess relative degree of inhibitory effects against the test microorganisms: Staphylococcus aureus, Esherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia and Lactobacillus respectively.. The zones of inhibition for K. pnemonia was the highest with 4mg/ml methanol extract of C. nitida and least for E.coli. As for C. acumunata, zones of inhibition for Lactobacillus was the highest with 4mg/ml methanol extract and least for P. aeruginosa. Highest zones of inhibition progressively increase from methanol to aqueous extract as their diameter of inhibition increases with increase in their concentration. The overall implication of the antimicrobial potentials of C.nitida and C . acuminata in the development of drugs against infectious diseases and subsequent health improvement was highlighted.

This article presents an original concept of establishment of international regional law as a branch of international law at the present stage of social development. The legal system is constantly being updated with new branches and sub-branches of law, institutions, and norms, which makes it more efficient overall. The study of integrational processes in the conditions of development of geopolitical competitiveness, active formation of new regional economic, social, and military-political spaces, demands mobilization of not only political, social, and economic resources, but also legal. A complex analysis of integrational processes within the framework of current regional formations allowed the author to determine a number of signs such as fusion and interconnection of national interests, which ensures balance of national interests of the member-states of regional formation on one hand, and the interests of the regional formation itself on the other. The author substantiates the conclusion that creation and functionality of such regional formations is impossible without presence of international regional law, the element of which can possess certain level of autonomy with regards to both, national law of the member-states, as well as the international law.

Improper comprehension of the prescription can lead to wrong drugs taken, misuse of the drug dosage, and ineffective drug action by not following the proper schedule, which was advised, or development of adverse drug reaction, which can be fatal. The objectives is to study if the patient can evaluate/understand the prescription correctly and to study the effectiveness of the communication between the patient and doctor. By a cross sectional study, 192 patients of VS general Hospital and Nagri Hospital were assessed for evaluation of prescription given to them by consultants between January to March 2015. Out of 192 students, 29 (15.18%) did not know and 163 (84.82%) did know the disease they are suffering from. 86 (44.79%) were not able to read the prescription. After analyzing the data collected via basic questionnaire, our study did show that patients might not be able to read the prescription, but the doctors did an excellent duty of explaining the prescription to their patients

The objective is to assess the Juvenile Social Interaction among Internally Displaced Persons At AL-Najaf AL-Ashraf City. A Descriptive study is carried out at Al-Najaf AL-Ashraf City/Ya-Hussain Road from February 10th to April 5th 2016. Sample consisting of (1350) children were selected randomly. Data collected by used questionnaire, which includes the first parts was about demographic characteristics of mother (gender, age, number of sibling, order of student in the family, father and mother alive, parents social status, father and mother educational levels and socio economic status) .while the second part about social interaction for children. The present study concluded that most of the Internally Displaced children have social interaction problems. The study recommends to increasing the children cognitive in schools and social support and detected the problems that psychological traced

Complexes of Schiff base were synthesized by direct condensation of acetaldehyde with thiosemicarbazide in the presence of FeCl3.6H2O and CuSO4.5H2O. The products were characterized by elemental analysis, molar conductance, infrared as well as electronic spectra study. The complexes are of 1:2 (metal:ligand) stoichiometry and are non-electrolytes in solution. On the basis of these spectra data, the general formulas: Cu(ADTSC)2SO4H2O and Fe(ADTSC)2Cl2.3H2O and an octahedral geometry was proposed for the complexes. The ligand and its complexes were screened for their antibacterial activities against Salmonella typhi, Shigella sp, Escherichia coli, Klebsiella sp, Staphylococcus aureus Pseudomonas aeruginosa and Vibrio cholera. The results of these studies showed that the metal complexes displayed more antibacterial activities against most of the species as compared to the uncomplexed ligand. The minimum inhibitory concentrations (MICs) of the compounds were also determined by two fold serial dilution method, the results showed an MIC value in the range of 500-250 µg/ml for the free ligand and 250-62.50 µg/ml range for the complexes. Results obtained from the toxicity effects of administration of the ligand and metal complexes at the doses of 25 and 50mg/kg body weight daily for 5 days showed that both doses of acetaldehyde thiosemicarbazone significantly increased (P<0.05) the levels of AST, ALT and ALP when compared to the control group, 50mg/kg body weight of acetaldehyde thiosemicarbazone copper(II) complex equally increased significantly(P< 0.05) the level of ALT based on comparison with the control group. The toxicities of other compounds were considerably non-significant (P≥ 0.05).

1, 3-Thiazine based compounds continue to yield promising antimycobacterial, antibacterial, antipyretic, anti-inflammatory, analgesic, antitumor, and antioxidant agents. The success of these compounds has been based on simple and cost effective synthetic routes and the presence of N-C-S linkage in its scaffold. A number of studies have been reported in the recent years to investigate different biological activities of 1, 3-thiazines. There are different classes of 1, 3-thiazines in the literature which can be divided in to natural and synthetic 1, 3-thiazines. There are several structural classes of synthetic 1, 3-thiazines such as 1, 3-thiazines as dihydro-1, 3-thiazine derivatives, 1, 3-thiazine spiro-derivatives and thioethers; 1, 3-thiazines with heterocyclic rings such as pyrimidine, pyrazole, thiazolidin-4-one and 1, 3, 5-triazine moiety; 1, 3-thiazine-2-amine, amide and hydrazides; 1, 3-thiazines with Schiff’s bases. Herein natural and synthetic 1, 3-thiazine possessing molecules and their therapeutic actions are discussed

This case describes the management of a 12 year-old boy with mild hemophilia A, who was referred to Department of Pediatric Dentistry for orthodontic extractions. This case was treated under Desmopressin and tranexamic acid cover with caution related to local anesthesia administration technique which highlighted the importance of close and detailed liaison with the hematology team to formulate a comprehensive treatment plan.

This study investigates the job burnout components impact on manufacturing workers job commitment since burnout known as a syndrome that influences employees’ motivation and their commitment level. As well, each organization also aims to increase the company profit and productivity by reducing the level of strain among their workers which may reduce the performance and commitment level. The present study also aim to investigate if there is any significant relationship between emotional exhaustion, personal accomplishment and depersonalization towards job commitment among the manufacturing workers in Melaka. There have been limited study done in manufacturing sector and this study focused on manufacturing sector, in order to minimize the negative effect on employee productivity and their commitment level. The Maslach Burnout Instrument-Human Service Survey (MBI-HSS) and Employee Commitment Survey (ECS) were used in this study. This study examines the direct relationship between emotional exhaustion, depersonalization and personal accomplishment on job commitment. A quantitative approach with descriptive analysis method and multi-stage sampling method were used in this study. Where, cluster method was conducted followed by stratified and simple random sampling method. A total of 780 questionnaires were distributed to the manufacturing workers in Melaka who had agreed to participate in this study. However, out of it only 518 questionnaires were returned and about 383 questionnaires were usable for further analysis. Results showed that emotional exhaustion and depersonalization were significantly negatively associates with job commitment while personal accomplishment was significantly positively associates with job commitment.

Complete cleaning and shaping of the root canal system is essential for success of endodontic treatment. Accurate measurement of working length and 3D obturation till the apical constriction is necessary for ensuring fluid tight seal. One of the disadvantages of overextended root canal obturations is post-operative pain. The treatment options in such cases are endodontic surgery to remove the extruded filling material or Intentional Replantation. This case report discusses the advantages of Intentional Replantation and the procedure involved in endodontic retreatment of a mandibular molar with this technique.

“Drug – induced” or “medication- related” forms of enteropathy are known to result in alterations in small intestinal architecture and function causing “sprue- like” mucosal changes, diarrhoea and malabsorption. Many drugs are proved to induce these changes and these include chemotherapeutic agents like colchicine, vincristine, and immunosuppresants like methotrexate, azathioprine, mycophenolate mofetil [1]. Several cases of villous atrophy following use of immunosuppresants are reported. But, literature search revealed only two cases of intestinal villous atrophy secondary to methotrexate [2]. We present this third case of sprue- like syndrome secondary to methotrexate treatment in a psoriatic patient

Implant supported Over dentures are prescribed in order to enhance retention, support and stability. Over denture is the treatment of choice when lip or facial support is required. Implant supported over dentures have been found to be very useful prosthodontic treatment modality. A number of case reports suggest the use of customized implant abutments in order to enhance esthetics as well as to rehabilitate excessively angulated implant fixtures. Several studies have indicated the use of stress breaking as well as soft relining material which would have a protective effect on perimplant tissue. This article will throw a light on the use of customized implant abutments as well as soft relining material in an maxillary implant supported over denture.