This paper demonstrates the imperativeness of public participation if the people who are entrusted with leadership in a country misgovern amid the watch of constitutionalism. For social justice to occur—for the vast majority of Kenyans to access healthcare, adequate housing, adequate and nutritious food, safe water, social security, education, to ensure their well-being—governance is the sine qua non. It is not governance per se, but governance that is participatory: a type of governance that values the views of the governed. Kenya, with a population of approximately 50 million, has over 45 per cent of its people living below the poverty line or on less than two dollars a day while some citizens have by far more than they need. The East African country is regarded by the World Bank, UNDP and other authorities as one of the most unequal countries in sub-Saharan Africa. Because of this huge divide between the haves and the have-notes, the country is far from attaining social justice. For social justice to be achieved, social problems have to be mitigated. This is only achieved if people have access to the basic needs such as clean water, food, healthcare, and clothing. But then again, social justice cannot be achieved without public participation, accountability, transparency, effectiveness and efficiency, equity and inclusiveness, responsiveness, and the rule of law. Through literature review, it is clear that participatory governance boosts not only equality and equity, but also efficiency and effectiveness in service delivery, alleviation of corruption, ineptitude, laxity and inertia, and empowerment of the people in their quest to expand their choices.

The article established the relationship between youth livelihood program fund and unemployment reduction in relation to gender in western division, Kabarole District. The study adopted an observational, cross-sectional exploration design with both quantitative and qualitative as paradigms in order to describe the data and its characteristics. Questionnaires, interview guides and focused groups discussions were employed to garner information from the respondents. Data was analyzed using frequencies, percentages and bar graphs. The study findings showed that there was a positive correlation between youth livelihood program fund and unemployment reduction in relation to gender. The study findings recommended that training of the youth groups should be handled on a case by case basis depending on the nature of the enterprises specialized in while considering the group dynamics. There should be regular follow up by the relevant offices to save the situation before it runs out of hand, increase the operational (monitoring) funds for the projects across the board. There is need to ensure capacity building of both men and women to improve their financial management and entrepreneurship skills, give males and females equal opportunities and treat them equally and have equal and easy access to the funds, the study also suggested that both males and females should be involved in policy making processes of their own groups so as to feel a sense of belongingness of their own projects.

Superficial fungal infections are generally more prevalent in tropical environments because of the enhancement of their growth by the high temperatures and high humidity conditions prevalent in these regions. The aim of this study is to investigate the antifungal potency of herbal ointments formulated with aqueous extract of Cassia alata. The in vitro antifungal activity of crude extract of leaves of Cassia alata as well as herbal ointments were determined against Candida albicans, Trichophyton mentagrophyte, Aspergillus niger and Penicillium using the Agar cup plate method. Herbal ointments were prepared by incorporating the crude extract of Cassia alata (10 % w/w) into ointment bases and evaluated for their in vitro antifungal efficacy. The crude extract showed moderate antifungal activity against Candida albicans, Trichophyton mentagrophyte and Aspergillus niger with zones of inhibition of 23 mm, 21 mm and 19 mm respectively at 200 mg/ml but no activity against Penicillium. The antifungal activity was retained in the herbal ointments with higher zones of inhibition for corresponding concentrations. The formulation containing Cassia alata extract in aqueous cream showed comparatively better antifungal activity. The herbal ointment also compared favourably with a commercial brand of Miconazole cream used as standard. This study shows that Cassia alata possesses antifungal activity and also has high potential as antifungal agent when formulated as ointment for topical use and could therefore explain the successes claimed in the folk use of the plant in the treatment of common skin conditions, hence the need to have herbal topical dosage forms.

Ectopic pregnancy is an entity which when reports to emergency department requires prompt diagnosis and treatment. Index of suspicion is high in fertile women but it poses challenge and demands knowledge to manage if the woman has history of sterilization where suspicion of pregnancy is far remote. We present one such experience of ruptured ectopic pregnancy in a woman who had history of bilateral tubal sterilization 6 years back.

This paper attempts a reinterpretation of European colonisation of Africa with particular reference to settler and non-settler colonies in Africa. Colonial system whether it is “indirect rule” practiced by the British, the French “assimilation” and “association”, German “paternalism”, Portuguese “Luso-tropicalism” etc have the same motives and tendencies aimed at exploitation, peripherialisation and pauperisation of the African people in all parameters for their material benefits. The methodological approach adopted in this research is “qualitative method”. Secondary source materials have been utilised, which comprised mainly published books that have been critically analysed. In the findings, why some colonies have been inhabited by white settlers while others not and why the settlers did not vacate after independence and the implications of this development in Africa. This paper also attributed most of the present conditions and situations in Africa to be connected to colonial legacies. These include conflicts of different kinds, militancy, social dislocation, complexity in Africa as well as neocolonialism. It has been observed that colonial conquest of Africa resulted in strangulating the African societies and making them dwarf and the bereft of mental initiatives towards societal development.

The study presents a survey designed to measure levels of intrinsic and extrinsic motivation in Saudi learners of English in the United Kingdom. As part of the study, a 32-item structured questionnaire and some open-ended questions were administered to a randomly selected sample of 80 Saudi learners who were studying either Academic or General English in various language institutions and universities across the UK. Data collected through the survey were subjected to some basic statistical analyses, such as "mean" and "standard deviation", inferential statistics, such as correlations and ANOVA, and thematic analysis for the open-ended questions. Based on the results from the analysis, a number of generalizations and conclusions were made in relation to the role of motivation in learning English for Saudis temporarily studying in the UK educational setting. In addition, some recommendations are offered, which can help Saudi teachers and learners of English achieve better learning outcomes.

Postoperative period is very crucial from recovery point of view. For fast and smooth recovery, postoperative period should be free of complications especially pain. It became more important in case of ceaserean section as patient also has to look after her baby. Cautious use of analgesic drugs has to be made in postoperative ceaserean section patient as they can adversely affect health of the baby also. Intraperitoneal instillation of ropivacaine is effective analgesic and has lesser side effects than pharmacological drugs. Our hypothesis is that intraperitoneal instillation of ropivacaine reduces postoperative pain in patients undergoing ceaserean section. This randomized control study was conducted on 60 patients of ASA grade 1 and 2 after taking ethics committee approval. Group I (n=30) is control group with no local infiltration and Group II (n=30) Local infiltration of 15 ml at incision site and intraperitoneal instillation of 5ml Inj. Ropivacaine 0.2%. Diastolic, systolic and mean blood pressure, heart rate were measured throughout the procedure. Time of rescue analgesia and VAS score was recorded postoperatively. Intraperitoneal instillation of 0.2% ropivacaine provides postoperative analgesia. Mean duration of rescue analgesia in group I was 115.67±4.09 that was significant (p<0.05) in comparison to group II 170.33±3.69. intraperitoneal instillation of 0.2% ropivacaine reduces postoperative pain in patients of ceaserean section under spinal anaesthesia.

Virtual Learning Environment (VLE) in higher learning institutions presents a podium for academic material accessibility that entails creation, evaluation, communication and general course administration with customizable interfaces. Virtual learning environments are online based platforms which are used to ease the student’s course content access and improving learning ability. Virtual learning environments bear features such as collaborative tools, embedded external recourses, detailed reporting logs, roles and permissions and calendars. However without finding out the factors for the low adoption rates, the effort to implement VLE remains in question. This paper discovers the factors that have brought about the low adoption rates of VLE in higher learning institution. The study adopted both qualitative and quantitative case study research approach and a purposive (non-probability) sampling technique where both staff and student respondents were selected from the case study institutions. A survey questionnaire was administered to 22 staff members and 305 students making a total of 327 respondents using Chris Morgan (1999) formula for sample determination. The results indicated power fluctuations, poor internet connections, and luck of management support, slow computers, and skills to access the VLE platforms as the major factors. The research suggests that, institutional readiness assessment, Virtual learning environments implementation framework, implementation policy formulation, training of trainers and improving the infrastructure should be given a high priority if VLE are to be successfully implemented in higher learning institutions.

We had investigated the xanthine oxidase inhibitory activity and uric acid lowering effect of newly marketed xanthine oxidase inhibitor, febuxostat and compared its effect with allopurinol in vitro. In hyperuricemic animal model serum uric acid, lowering effect of these drugs was evaluated. Serial dilutions of febuxostat and allopurinol were made, ranging from100 µg/ml to 0.75µg/ml. Xanthine oxidase inhibition was carried out in vitro. Hyperuricemia was induced in Wistar rats by potassium oxonate injection on day 1, 3 and 7. Febuxostat and allopurinol (5mg/kg) once daily was given for 7 days. Serum uric acid was measured on day zero, 1, 3 and 7 by uricase method. Michaelis Menten equation was applied to calculate IC50, Vmax and Km. IC50 of allopurinol and febuxostat were 9.07 and 8.77 µg/ml respectively. Km and Vmax of febuxostat were 8.89 and 107.13 where as allopurinol showed Km 7.77 and Vmax 194.14.Graded dose response was observed for both allopurinol and febuxostat. Hyperuricemia was successfully induced with potassium oxonate. Treatment with allopurinol reduced serum uric acid levels up to 3.21±0.8mg/dl on day 7, but reduction was less than febuxostat 0.81 ± 0.12 mg/dl. From this study, we have concluded that febuxostat is an effective option for cases of hyperuricemia.

Higher education is not a form of cost but is one form of investment. This form of return can be in the form of a high bargaining value when the relevant person gets a job offer. Higher education not only has economic value in individuals, but in society One of the economic values of higher education is the existence of employment opportunities for the community when higher education is held in a location where economic value can be in the form of employee recruitment or the opening of new jobs in the informal sector for the surrounding community. The challenge for the education sector is to develop educational systems capable of improving basic education equity, education quality and relevance of education to development needs, as well as science and technology education. Because everything that has been proven to have direct and indirect impact on economic growth of the Indonesia Economic.This study uses a qualitative approach with study methods case. The data analyzed is the result of interviews with the field of service and direct observation in the field of services and general fields, and review documents at Private Universities in Surabaya

The aim of the present study was to increase the solubility and thereby improve the oral bioavailability of Furosemide by incorporating the drug in nanostructured lipid carriers (NLC) and in solid lipid nanoparticle (SLN) and also to compare the efficiency of NLC over SLN. Both the NLC and SLN were prepared by solvent diffusion method using labrafil m 2130 as solid lipid, capryol pgmc as liquid lipid, and tween 80 as surfactant. Properties of Furosemide loaded NLCs & SLNs such as drug content, entrapment efficiency, loading capacity, particle size, PDI , zeta potential, morphology, storage stability, in vitro drug release and mechanism of drug release were investigated and compared. Drug content, entrapment efficiency, loading capacity, average particle size, PDI and zeta potential of Furosemide NLC were found to 83.56%, 75.50%, 25.63%, 99.24nm, 0.302 and -31.2mV and that of Furosemide SLN were found to 84.55%, 71.07%, 24.62%, 193.4nm, 0.835 and -36.1mV respectively. Morphology study by scanning electron microscopy (SEM) analysis showed spherical particles with smooth surfaces. As compared to in-vitro drug release of Furosemide pure drug, both the NLC and SLN showed fast initial release followed by a sustained release, best fitted to Higuchi equation. Pure drug followed Zero order release kinetics. Furosemide NLC showed higher entrapment efficiency, drug loading capacity, in-vitro drug release, reduced the drug expulsion in storage when compared to SLN. This investigation demonstrated the efficiency of NLC over SLN for improved oral bioavailability of Furosemide and it was deduced that the liquid lipid (capryol pgmc)was the principal formulation factor responsible for the improvement in characteristics and pharmacokinetics of NLCs.

This study was designed to investigate the influence of Postate cancer awareness campaigns on the knowledge, attitude and practices of men in SouthEastern Nigeria. The study employed the survey method of enquiry. The population of the study is 8,184,951 adult males in South-Eastern Nigeria. Five research questions guided the study. The data was analysed using Statistical Package for Social Science (SPSS). The result of the data analysed revealed that the awareness and knowledge level on postate cancer is relatively low among the men in South-Eastern Nigeria. Also, most information on postate cancer were made known to the respondents by medical practitioners, however, those respondents that are exposed to the campaigns agreed that the campaigns have influenced their behavior positively. The study recommends that, awareness campaigns should be well structured both in English and the target audience local language to sufficiently and effectively convey the Prostate cancer campaign messages. Thus, the risks and the effects of the negative attitudes of men towards this campaigns must obviously be stated citing relevant examples. Also, campaign planners should involve the target audience/opinion leaders as participants in the campaign and too, lower the age for screening, so that early detection and prevention can be detected before it becomes late. There must always be emotional, physical and psychological appeal in the campaign messages.

А device for the isolation of nucleotide complex from biomass of Saccharomyces cerevisiae cells was developed, and the biological active substances in the extract were analyzed. The isolated nucleotide preparation can be used to stop oxidative stress and improve immunity. The developed device allows extraction of biologically active substances from Saccharomyces cerevisiae cells in series by extractants: distilled water under the action of an alternating voltage with a frequency of 105 Hz, a solution of hydrochloric acid with pH = 1.0-1.5 without using voltage. After acid extraction, the extract was neutralized with sodium hydroxide solution. The extracts obtained were combined and dried. The technical result of the device is a more complete two-fold extraction of the nucleotide complex from native Saccharomyces cerevisiae biomass. The use of our constructed device makes extraction of biologically active substances easier and complete. The content of biologically active substances, such as adenine nucleotides, amino acids, vitamins, micro-, macro- elements in the obtained extract was analyzed. A comparison of the activating effect of the isolated nucleotide preparation on Ca2+-dependent NO - synthase with T-activin was performed. Experiments showed that the nucleotide preparation, obtained by new device has a pronounced activating effect on Ca2+ -dependent NOS from rat thymocytes.

This study aims to analyze the behavior of the use of Information Systems in registered taxpayers at the Palembang Middle Tax Service Office through the Unified Theory of Acceptance and Use of Technology. Specifically the purpose of this study was to examine trust in government, hedonic motivation, and social influence on the Behavior Intention and User Behavior of e-faktur and test Behavior Intentions towards User Behavior of e-faktur. This research is Quantitative Descriptive Research. The sampling method is proportional stratified random sampling method. The number of samples was 282 respondents are director and accounting major in company who registered in Middle Tax Service Office Palembang. The method in this study is statistics using SmartPLS 3.0. The results of this study indicate that trust in government has a significant effect on Behavior Intention whereas behavior does not have an effect as well as Hedonic Motivation which has a significant positive effect on behavioral intentions while behavior does not affect. Social Influence does not have a significant effect on the Behavior Intention and User Behavior of e-faktur. As well as Variable Intentions of Behavior towards User Behavior e-faktur has a significant effect. In the next study we suggested adding gender, age, experience and voluntary variables.

Multiple sclerosis (MS) is an important cause of neurological disability. Familial MS is uncommon in India and is seen mostly in the high prevalence countries like United States of America, Canada and New Zealand. In the present paper, two members of the same family were diagnosed as having MS. As the disease is uncommon, there was initial diagnostic difficulty in the first case. The clinical and radiological findings are described with a note on the treatment and follow up.