Implementation of herbal medication is traditionally employed for treating broad spectrum diseases. Among this remedial flora, Nigella sativa is emerging as potent pharmaceutically significant plant with supportive religious background. Produce formulated from N. sativa have been found effective as anti-inflammatory, analgesic, antipyretic, antimicrobial, antineoplastic drugs for various disorders and also as an ideal healer for variety of wounds. As in daily routine, minor injuries, abrases and burns are common and inevitable. In consequence, wound healing which is a physiological and systematic process in response to injury may be impaired due to several external and internal factors like in case of several infections and in diabetic patients, and it may lead to diabetic foot ulcers with significant morbidity and mortality risks. Retarted diabetic wounds’ healing is mainly due to interlukin-8, hyperglycemia and other contributing factors are like poor epithelialization, angiogenesis and skin regeneration. Biochemically, black seeds contain 35% fatty acids, 21% proteins and 38% carbohydrates and vast variety of other vitamins and minerals. Among them, thymoquinone frequently reported constituent as potent wound healer either of diabetic origin or due to other reasons. So far explored broad spectrum efficacy of this plant is also directly a proof of hadith of Prophet Muhammad (UBPH(: ―Use black seeds regularly; because, it cures every disease excluding death‖. So its biochemical screening and dose optimization to cure and heal not only the diabetic wounds in better way but also for other pharamcognosal pursuits should be explored in future to provide general public of third world countries like Pakistan, as local cost effective alternative drug in replacement of expensive synthetic drugs for better medical treatment.

This research was conducted on the basis of a violation of the sale and purchase of plots of land which continued the construction of residents' houses in the East Coast Surabaya (Pamurbaya) protected area. Protected areas are areas that are defined by the main function of protecting environmental sustainability which includes natural resources and artificial resources. Included in the Pamurbaya area are Gunung Anyar District, Rungkut District, Sukolilo District and Mulyorejo District. This research also explains the implementation of the Government in fulfilling the right to adequate shelter to the community but on the other hand protected areas are very important for cities. Eviction or control is considered a good solution, but needs to be studied in advance regarding the impact caused by the control. In this study, we will discuss the steps to restore the function of the East Coast Surabaya (Pamurbaya) protected area, the impact on the fulfillment of the rights of the people who are at Wisma Tirto Agung Phase IV, and the impact caused by eviction. This study uses qualitative analysis methods, types of sociolegal research, as well as an empirical juridical approach, researchers collect all the data needed both primary data sourced from interviews or other secondary data. The results of this study indicate that the Surabaya City Government has not provided a clear solution to the cases that occur, residents of Wisma Tirto Agung stage IV remain in their homes. The plan to restore the function of protected areas by conducting evictions is still in the assessment stage because the Surabaya City Government cannot decide on evictions without regard to the rights of the community to have a decent place to live. In carrying out evictions, of course there are impacts caused. Can be seen from the psychological, economic, and social aspects.

This study aims to examine: 1) the effect of tax avoidance on earnings quality; 2) the influence of corporate governance on earnings quality; and 3) Effect of leverage on earnings quality; The research method used in this study is descriptive and verification. The population target in this study is banking companies listed on the Indonesia Stock Exchange (IDX) with observations in 2012-2017. Data to be used in research is secondary data in the form of data from annual reports and company financial statements. Validity and reliability testing is done before testing the hypothesis. This study uses the SPSS Version 25 analysis technique. The conclusion of tis research shows that tax avoidance, institutional ownership, independent commissioners, independent auditor, and leverage affect the quality of earnings by 31.1%. Almost 69.9% is explained by other variables outside the model.

This study investigates the link between organisational ergonomics and academic staff performance in federal universities in the South-South zone of Nigeria. It sought to examine the extent of the influences of three organisational ergonomic dimensions (teamwork, job design and effective communication) on the research output- a proxy for academic staff performance. A total of 7,086 academic staff constituted the population of the study. Primary data were collected from a sample of 1,236 respondents that were drawn from the population using the questionnaire. Data obtained were analysed using descriptive statistics, Pearson product moment correlation and multiple linear regression techniques. Results revealed that teamwork had the highest significant level of influence on the research output. This was followed by job design and effective communication. It was therefore concluded that organisational ergonomics has a significant positive influence on the research output of academic staff. Hence, management of Nigerian universities should prioritise the practice of organisational ergonomics and also pay attention to the implementation of policies that would encourage research collaboration among academic staff in their institutions

This paper x-rays the meaning of scientific literacy and compares it to how science is taught in Nigeria schools, in order, to know how Nigeria has fared in making her citizens scientifically literate. It was concluded that science teaching in Nigeria schools were meant for students to pass examination and not to feel the impact for societal growth. The consequences are that most farmers do not want to use fertilizers, graduates in science and applied science are highly superstitious, people do not know that brakes can fail, that sickle cell disease is genetic and not from evil spirits e.t.c Therefore, the impact of science is not felt. It was recommended that science curriculum should emphasis on why science, organize workshop for teachers on linking science to the society, so that the people would feel comfortable knowing what science is all about, even though they do not know much about science.

This paper uses conceptual blending theory to study the emotional poetic metaphors related to flowers in A Dream of Red Mansions. Exploration of how these emotional poetic metaphors are related to flowers in constructing meaning achieves the creative intention of the author. The proposal of this paper also reveals the "cognitive iceberg", which is hidden in the emotional poetic metaphors related to flowers in A Dream of Red Mansions so as to provide the readers with a wider range of reading horizons. Because human emotions are highly abstract, people tend to use metaphors to vividly express these abstract emotions. In A Dream of Red Mansions, the poet uses a lot of emotional poetic metaphors related to flowers to express the characters’ various inner emotions, including sadness (including loneliness, worrying, longing, hopelessness, helplessness, despair, etc.), happiness, and pride. These emotional poetic metaphors are mainly constructed by using the images of appearances, characteristics, periods, colors, fragrances, and growth environments of flowers. Through this analysis we can understand the metaphorical process, which projects from the flowers to human beings, is actually a process of conceptual blending. Through the mechanism of conceptual blending, the poet projects the flower onto human beings, using the flower to metaphorize human beings, making the abstract things more concrete while making the strange things more familiar, so as to facilitate comprehension and offer a deep impression. In addition, every poetic metaphor should be rooted in a certain cognitive model and culture model. In the process of conceptual blending of poetic metaphor, cognitive models and culture models play very important roles. The cognitive model provides certain possibilities for the formation of poetic metaphor, and the culture model is the key factor which allows these possibilities to become a reality.

This study aims to observe and determine the relationship of Islamic banking learning to saving interest in FKIP students at Muslim Nusantara University (UMN) Al Washliyah in Islamic banks. This research is a descriptive-quantitative study with 56 samples of UMN Al Washliyah Medan students. Based on the results of the study there is a significant relationship between product learning, Islamic bank services to interest in saving students in Islamic banks. The output of SPSS data shows that product variables, service variables and saving interest variables can be concluded that the value of F Change is 0.000 <0.05, so there is a significant correlation with the degree of moderate correlation relationship where the correlation coefficient is 0.524 located between 0.41 to 0, 60 on the Pearson correlation value.

At the center of the investigation of this study is the organizational complexity of the school The problem area concerns the (Italian) School with its articulations that presents a series of evidences and criticalities that deserve reflection. Instrumental functions (the middle manager), in Italian schools, represent temporary positions, which interpret and represent an organizational model anchored to the functioning of intermediate roles and support to the management strategies of the School system, but with little identity. The temporary nature of the assignment and its electoral nature also failed to guarantee the legitimacy of this role. The problems are very controversial with which we reason in the Italian context. It is not clear whether it is the middle management, that is, middle managers who collaborate with the head teacher in the exercise of predominantly organizational-managerial functions or, rather, if they represent figures expressed by the college of teachers because they are capable of interpreting the "vision" of the school, to gather the best professional energies. The results of the study seem to confirm that middle managers possess different characteristics of professional figures even if they are not officially known within the school's organizational structure.

Anaplastic carcinoma of thyroid is a rare high grade neoplasm with unfavourable prognosis, accounting for less than 5% of all thyroid malignancies. It is responsible for high mortality and morbidity rate due to aggressive nature of carcinoma. Anaplastic carcinoma of thyroid is infrequently reported in the literature. Here we present a rare case of anaplastic carcinoma of thyroid in a 77 year old female who presented with large neck swelling.

The objective of this study was to determine the impact of promotion on job satisfaction and organizational productivity among staff of Usmanu DanFodiyo University Sokoto, Nigeria. Sample was selected through stratified random sampling technique and data was collected from 341 staff (academic, senior non-academic and junior staff) category of the university, out of which 308 questionnaire was retrieved and therefore, analysis was based on the 308 returned questionnaire. The analysis was done with the use of SPSS software version 21, using descriptive analysis to describe demographic characteristics of respondents, Pearson product moment correlation to test the relationship between the variables while chi square and regression was also used in analyzing the data obtained from the field. The result indicated that there was positive significant relationship between promotion opportunity and job satisfaction. The study therefore, recommends that organization should consider promotion variable as a means of retaining best brain and reduce brain drain in the organization

Background: Dermatological lesions display a wide spectrum of diseases. Although common in the developing countries, they are not considered significant on assumptions of being always non-lethal and insignificant but are sometimes indicators to underlying systemic diseases. Aims and objectives: To observe and analyse the spectrum of dermatological disorders through histopathological examination. Material and Methods: This was a prospective study, carried out at tertiary care centre of Ahmedabad, Gujarat, India. A total of 127 cases including punch and excision biopsies of skin were studied over a period of 1 year and 6 months. Results: Out of the total 127 cases, 56 were males and 71 were females showing a slight female predilection. Skin lesions were divided into six groups of which inflammatory, malignant & benign neoplastic; & infectious skin lesions showed female predilection while spongiotic, psoriasiform and lichenoid skin lesions as well as leprosy and tuberculous skin lesions showed male predilection. Vesicobullous lesions were found to be gender neutral. The overall male to female ratio was found to be 0.8:1. Inflammatory lesions (33%) of skin formed the most common group of skin lesions in this study followed by benign tumours/cysts (27.5%) of skin. Conclusion: Skin lesions show a wide variety of histomorphology and they are sometimes an important manifestation of systemic diseases. Hence, a proper histopathological examination remains the gold standard in diagnosing skin diseases.

Summary: Due to its impact and its epidemiology, the black Sigatoka disease caused by Pseudocercospora fijiensis is a multidimensional problem, given the insured nutritional and economic importance by the banana and plantain in our region. The limits of existing therapies and especially the inaccessibility to the latter as well as the consequences in the environment and the health lead to the search for new sources. It is in this framework that this work has focused on the evaluation of the antifungal activity of extracts from 14 plants used in traditional medicine against fungal infections of the human resources in the Kisangani region. It has been tested by the method of inhibition of the growth of the mycelian explantant on Potato Dextrose Agar (PDA) medium in a Petri dish. The main results obtained show, after the evolution of the diameters of growth of mycelian explantants on media containing different extracts compared to the diameter of the light during the incubation period, that all plants tested have antifungal effects at different levels and/or moments during the incubation. And these effects have been observed either during the entire incubation period, or at the beginning of the incubation, or toward the end of the incubation, or only slowed growth in relation to the witness without as much completely inhibiting it. Carica papaya has been the only plant having kept its inhibitory effect complete for all forms of extracts tested.

Background: Candida infections are among the most common fungal infection affecting immunocompromised patients in various disciplines of the health care system. In recent decades, due to dramatic increase in invasive fungal infections and related more common use of the antifungal therapy, resistance to antifungal agents has become an issue. Objectives: To determine the prevalence of candida species in various clinical specimen & their resistance to azole group of antifungal agents. Materials & Methods: This study was conducted at tertiary care hospital during January 2014 to June 2015. Total 23,896 samples (urine, blood, high vaginal swabs, oropharyngeal swab, body fluid, corneal scrapping, etc) were received over study period. Result: Out of total 8864 culture positive specimen, candida species were isolated in 644 specimens. Among total 644 Candida isolates, C.albicans is the most prevalent species (44%). Amphotericin B (99.6%) had the maximum rate of susceptibility amongst all the antifungal agents, followed by Voriconazole with 94.8% susceptibility. Fluconazole, Itraconazole & Miconazole were 73.3%, 73.44% & 74.22% susceptible respectively. Conclusion: Azole derivatives represent one of the major groups of antifungal drugs used in clinical practice to treat fungal infections. Empirical usage of Fluconazole in immune-compromised patients appeared to have played a major role in rising emergence of non albicans species resistant to Fluconazole.

The first level health facility is the spearhead of the first level health data collector for the health office in the territory of Indonesia, in supporting the National Information System development strategy. The management information recording and reporting system as a means of supporting the processing of health data in first level health facility will be useful in producing quality information that is used as a basis in making decisions to establish health programs. This research is a descriptive study with a quantitative approach to measure the description of perceptions and implementation constraints faced by users of the management information recording and reporting system. The survey was conducted on 59 respondents by answering questionnaire questions. Based on the results of the study, the perception of the use of the management information recording and reporting system produces a good perception. While based on perceptions of acceptance: officers aged 36-45 years at tambakaji health centers are better than Ngaliyan health centers. Officers with female gender are the least likely to encounter obstacles, while officers with <5 years of work are most vulnerable to problems. The management information recording and reporting system is very supportive in operational activities in first level health facility.

Background: Large intestine and anal canal harbors various neoplastic and non-neoplastic lesions. Colorectal carcinoma is one of the leading cause of death. This study was aimed to evaluate and correlate the spectrum of various lesions of large intestine including anal canal in relation to age and sex of the patients and to compare the study done in our institute with other studies. Material and Methods: This one year study was done during the period of January 2018 to December 2018 in a tertiary care center which included 58 cases from large intestine and 16 cases of anal canal. All biopsies and resected specimens were fixed in formalin and stained with H&E and special stains like Periodic Acid Schiff (PAS) and Ziehl Neelsen (ZN) were done in required cases. Results: Out of 58 cases of large intestine 36 cases were non-neoplastic and 22 were neoplastic cases. 16 cases from anal canal were non-neoplastic lesions. Adenocarcinoma was the commonest malignant neoplastic lesion. Most of the cases presented with symptoms like bleeding per rectum, abdominal pain and constipation. Conclusion: The present study observed that non-neoplastic lesions were more common in large intestine and anal canal. There was a higher incidence in male patients. Neoplastic lesions were common in 3rd and 4th decade. Adenocarcinoma was the commonest among neoplastic lesions. This study also emphasizes histopathological evaluation is essential for early diagnosis of the tumors which will increase the survival rates of the patients.