This study highlights the characterization and biological activities (in vitro) of root extracts of Indigofera hirsuta (Ih-E) and Afrormosia laxiflora (Al-E). The results showed that total phenolic and flavonoid contents in dry Ih-E were 54.38 mg and 116.03 mg/gram, respectively, while in Al-E were 170.46 mg and 80.23 mg/gram. Both extracts exhibited antioxidant activities since they decreased lipid peroxidation, but increased antioxidant activities and anti-inflammatory activities as shown from inhibition of RBC haemolysis and inhibition of albumin denaturation. Also, they have cytotoxic effect against normal BHK-21 and HepG2 where IC50 for Ih-E were 309 µg/ml and 95µg/ml, respectively (selectivity index 1.58), while for Al-E 57.50µg/ml and 144.50 µg/ml, respectively (selectivity index 0.40). Ih-E has antimicrobial activities towards Pseudomonas aeruginosa, Staphylococcus aureus, Vibrio species and E-coli, while Al-E showed no antimicrobial activities. Conclusion: Both extracts possessed antioxidant, anti-inflammatory and anticancer activities, thus, can be used as pharmacological tools.

Honey bees are crucial in maintaining the biodiversity by pollinating number of plant species whose fertilization requires an obligatory pollinator. The European honey bee, Apis mellifera used by the bee keepers in Fiji is found as most economically valuable pollinator and has shown great adaptive potential against the variation in climate. The species is found almost on every agricultural crop worldwide and in highly diverse climates. In context to climate change, the variability in life history of Apis mellifera regards to temperature and the environment shows that the species possesses genetic variability; this could give rise to the selection of development cycles suited to new climatic conditions. Taking the above into consideration, it is to be examined the potential impact of climate change on honey bee behaviour, its physiology and distribution, as well as on the evolution of the honey bee’s interaction with diseases.

This study aims to determine the effect of the internal control system, information asymmetry, and environmental uncertainty on the budgetary slack at Manufacturing companies in the Cikarang Region, Bekasi. This research data collection technique used a questionnaire and was processed using the Partial Least Square (PLS) program. The results of this study indicate that the internal control system has a negative effect, while the information asymmetry and environmental uncertainty have a positive and significant effect.

This study was conducted with the aim to determine the effects of local government size, income per capita, local government wealth and audit opinion on the quality of internet financial reporting disclosures in local governments in accordance with Minister of Home Affairs Instruction No. 188.52/1797/SJ. The population in this study was all the official websites of the provincial governments in Indonesia, which covered 34 provinces. The samples in this study were all the official websites of the provincial governments in Indonesia with the observation years of 2015-2017, so the total amount of data in this study was 102 data (34 x 3 years). The samples in this study were selected using the survey data method on the official websites of the Provincial Governments in Indonesia. The results showed that the size of the local government had a significant effect on the quality of internet financial reporting disclosures in local governments, while income per capita, local wealth and audit opinion did not affect the quality of internet financial reporting disclosures in local governments.

In developing countries like Ethiopia where concrete is widely used there is a steadily increasing the cost of concrete. This made construction work very expensive, due to less availability of concrete ingredients. In recent years, the use of natural fibers is become increasingly common in the civil engineering sector, as a part of energy-efficient and sustainable trends. Several researches demonstrated good properties of sheep wool fibres which a basis for compressive strength, tensile strength and improve environmental issue. The paper was focus on investigation on effects of sheep wool usage as a concrete composite material in C-25 concrete. The investigation is very important because, at present, the knowledge and the application of sheep wool fibers in this sector are relatively limited in our country. So an attempt has been made to achieve improved strength results using sheep wool fiber in conventional concrete. Experiments were conducted on concrete cubes and beam of various percentages of sheep wool fiber such as 0, 0.5, 1, 1.5 and 2% by weight of cement were tested for their workability, compressive strength and flexural tensile strength. The sheep wool were collected from different sources and dipped into salt water for 2 days to make hair surface rough. The wool has been sun dried. The mix ratio for C-25 concrete specimen was done in accordance with ASTM 595 and ACI 544.1R-96. From the study workability of the mix was reduced as percentage of sheep increase. The optimum amount of sheep wool fiber to produce concrete was 1.5%. Using 1.5% of fiber increase concrete compressive strength, flexural strength and split tensile strength property. It can be concluded that using sheep wool fibered concrete were preferable particularly to improve flexural strength.

This study aims to look at employee performance, especially the Marketing Funding section at PT. Bank Danamon Indonesia Jakarta branch. The planned activities (1) Formulate problems. (2) Develop a frame of mind. (3) Arrange hypotaesis. (4) Perform data experiment / processing. (5) Drawing conclusions. (6) Reporting and scientific publications in ISSN journals.

The purpose of review article is to find herbal drug for treatment of some diseases. Several side effects came from chemical drugs. Use of non-chemical, non-invasive natural remedies have no major adverse effect because contain naturally active biological components, therefore they have paying much attention within recent years. Possible usage of leaf extract of Papaya for treatment of dengue fever promising cure for dengue patients. Pomegranate contains high level of antioxidants which make it one of the best fruits for boosting blood count. Phenolic compound extraction from extra virgin olive oil has immune modulatory and anti-inflammatory effects in Systemic lupus erythematosus (SLE) patients. Wound healing properties are exerted from aloe Vera gel. Fenugreek seed best natural remedy for Poly ovarian cyst syndrome (POCS). Garlic and ginger are organosulfur compounds consisting upon its bio actives having an important role in cardiovascular diseases and cancer respectively.Nigella sativa recently demonstrates the role in diabetes mellitus. Allium cepa. L (Onion) contain phytochemicals that have antidiabetic, anticarcinogenic, anti-inflammatory, antibiotic, antioxidant, antimicrobial and antiplatelet effects on the human health.

This study was undertaken to investigate the level of life stress among college students, and to compare differences in life stress level between different groups of time online spent daily. Samples of 191 accounting students registered in strategic management course at a selected public university in Bangkok, Thailand agreed to complete the online questionnaire through Google platform. Results indicated that the overall level of life stress among accounting students was at a medium level (M = 2.91, S.D. = .704). Analysis of this study also demonstrated that the most frequently stress relief approach used by this group of students was “consulting with a reliable person” whereas “seeing a psychiatrist” was reported as the least frequently stress relief method used. Additionally, a Kruskal-Wallis H test showed that there was a statistically significant difference in level of life stress between the different groups of time online spent daily, χ2(2) = 11.410, p = .003, with a mean rank life stress score of 82.13 for less than 5 hours group, 86.03 for 5-8 hours group, and 113.29 for more than 8 hours group, respectively.

Introduction: Ursodeoxycholic acid (AUDC) is the standard treatment for primary biliary cholangitis (PBC). Prescribing it at an early stage slows the progression of the disease and improves survival. Thus, the biological response to AUDC is considered as the main predictor of survival without liver transplantation. New scores, the Globe-score, and UK-score have recently been validated as the main prognostic factor during PBC. The purpose was to study the association between the Globe-score, UK-Score and the AUDC response during PBC. Patients and Methods: This is a retrospective study of all PBC cases treated by AUDC at a dose of 13-15mg/kg over a 22-year period (January 1998-May 2019). Treatment response was defined by the Paris II criteria at 1 year (a serum alkaline phosphatase (PAL) level 1.5 times the upper limit of normal (LSN), an aspartate aminotransferase (ASAT) level 1.5 times the LSN, normal bilirubinemia). The Globe-score and UK-PBC score have been calculated for all our patients. The statistical analysis of the data was done using the SPSS software. The comparison between good treatment responders and non-responders was made using the Chi2 test for qualitative variables and the Mann-Whitney test for quantitative variables. A combination of variables was considered statistically significant if p < 0.05. Results: During the study period, 90 cases of PBC were collected. There were 85 women and 5 men. The average age was 49 12.3. 52.3% patients (n=34) had a complete therapeutic response while 31 patients (47.7%) retained non-response after one year of AUDC treatment. The average Globe score for good responders was -0.62[-0.72; -0.36] and for non-responders was 1.53[1.32; 1.75] with a statistically significant difference (p0.001). The average UK-score value at 5 years; 10 years; 15 years for the correct answers was 1.8% [1.6-2.5]; 5.9%[5.2-8.2]; 10.7%[9.5-14.8] and for non-responders was 9.1%[6.7-9.9]; 27.4%[20.4-29.5]; 44.9%[34.6-47.8] respectively with a st

Money laundering is a phenomenon which undermines the country's economy and political stability. This phenomenon is a national and international concern. Put simply, this practice is the conversion of black money into white money. If done successfully, it will allow the perpetrators to maintain control of their results and ultimately provide legal protection for the sources of income of the perpetrators. Money laundering is playing a crime money to facilitate the ambitions of smugglers and terrorists. This research uses quantitative methods with descriptive analysis and primary data. The results of this study are that PT Asuransi Jiwa X already has and implements policies and procedures, Supervision conducted by the Board of Directors has been very effective and the company has a special work unit, has monitored and updated customers, reporting STR, has a list of terrorists and all employees new and existing ones have attended AML and CTF training and have been carried out by requesting information and supporting documents for prospective customers.

The aim of this paper is to identify the impact of negative reductions on negative questions in English which have different meanings in linguistics; semantic meaning and interpretation meaning. Auxiliary and Modal auxiliary have an order available to control all negative questions and those have interpretation meaning of positive assumption and negative assumption in the sentences. The important elements are needed as substantial ability of English grammar that non-native is able to speak and write English correctly. The data obtained from audio-longitudinal recordings of samples; narrative stories, descriptions of images form of negative questions. The research purposes of this study are (1) to know impact of negative reductions on negative questions in semantic based on the developmental category found in sentences, and (2) to know the types of negative questions in semantic using negative reductions which are largely made by categories. The descriptive method used in this study was qualitative; the data was extracted from Corpus data, library research, and conclusions. The results of study show that negative reduction appeared in global forms of various types of negative questions in English, It had different relationships and functions of meaning. In context; negative reduction provided basic terminology which, within this framework, will allow the birth of explicit relationships in the interpretation of meaning. Negative questions have founded all the negative rhetorical questions, yes/no questions and Wh/ H question.

In the current study, we tested the feasibility of using three species of imported plants to combat desertification in Saudi Arabia. Delonix regia, Jacaranda mimosifolia, and Simmondsia chinensis were chosen for the evaluation because they have previously been reported to have marked drought and heat tolerance characteristics. To examine the feasibility of using these non-native plants for the mitigation of desertification, we aimed to determine the evolutionary relationships between the imported and local plants. DNA extracted from the non-native plants was compared with that of 45 local taxa. Two genes, Maturase K (matK) and ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit (rbcL), were sequenced and aligned for all species of imported and local plants analyzed in this study. The two molecular markers are known to be evolutionary conserved. A molecular phylogenetic tree was generated using the local and imported plants, and it showed similarity between Delonix regia and Cassia senna, indicating that they belong to the same family (Leguminosae). Similarly, Jacaranda mimosifolia (a member of Bignoniaceae) was found to be closely related to the local plants Plantago ovata and P. arenaria. Simmondsia chinensis was determined to be distantly related to many taxa of flora found in Saudi Arabia. The results of molecular analysis and the physiological features of Delonix regia and Jacaranda mimosifolia indicate that both species are closely related to Saudi Arabia flora, more so than Simmondsia chinensis.

Antepartum Hemorrhage (APH) has always been one of the most feared obstetric emergencies which contribute to significant maternal and perinatal mortality and morbidity. Aims and objectives: To determine the causes of Antepartum Hemorrhage. To study the maternal and fetal outcome in various types of antepartum hemorrhage. Methods: It is a study conducted in OPD,Labour room and Intensive Care Unit(ICU) admissions in Department of Obstetrics and Gynaecology, Government General Hospital, Kakinada over a period of one year from April 2018 to March 2019 were analysed retrospectively. All cases of APH with gestational age more than 28 weeks whether diagnosed previously or during antental visits or during delivery, referred from other hospitals, emergency admissions are included in the study. Data was statistically analysed using SPSS 20 software. Results: The present study included 70 patients who was diagnosed as having placenta previa, abruptio placentae or APH due to undetermined causes presented with or without bleeding per vaginum in OPD, labour room,ICU. Majority of the patients (57.1%) had Placent previa while 41.4% had abruptio placentae; one case of APH is due to undetermined cause. Most of the cases of APH (64.3%) belong to the mean age group of 20-24 years both in placenta previa(57.5%) and abruptio placenta(75.9%) .65% of the cases are unbooked cases in placenta previa and 72.4% of the cases are unbooked cases in abruptio placenta. 90% of the cases of placenta previa are delivered by Caesarean section.55.8% of the cases of abruptio placenta are delivered by vaginal route.

Ovarian neoplasms have become increasingly important not only because of the large variety of neoplastic entities but more so because they have gradually increased mortality due to female genital cancers. Ovarian carcinoma represents the sixth most common female cancers and the fourth leading cause of death due to cancers in women. Surface epithelial tumors were commonest variety of ovarian tumors followed by germ cell tumors. Angiogenesis is a critical factor in tumor growth and metastasis, because tumor proliferation is severely limited by nutrient supply to proliferating tumor cells. Hence tumorigenesis of malignant neoplasms associated with extensive neovascularization. The analysis of tumor vascularization by microvessel density (MVD) and it’s prognostic significance has been evaluated in many tumors including ovary. Many studies have established MVD as an important prognostic factor in solid tumors, but there is paucity of literature regarding characteristics of the tumor blood vessels in ovarian surface epithelial tumors. The present study aims to evaluate not just the density of microvessels in ovarian surface epithelial tumors but also the maturity characteristics of proliferating tumor blood vessels with the aid of IMMUNOHISTOCHEMISTRY there by differentiating between benign and malignant epithelial tumors of ovary and predicting the prognosis. Objectives: 1) To determine the incidence of ovarian surface epithelial tumors at our hospital. 2) To clarify the differences in angiogenesis between benign and malignant epithelial tumors.

Background: This case study represented a patient’s case with a relatively uncomplicated arterial blockage of the Heart, and after prompt Yoga Prana Vidya (YPV) Healing, was successfully treated thereby avoiding costly bypass surgery. Initial medical investigation report stated 90% block in the arteries of the heart and recommended for open heart surgery. Methods: This is a case study method, going through full detailed records of the patient’s health conditions pre and post treatments using YPV healing system observed through lab test records, as well as data collected from follow-up interview of the subject. Results: Analysis of the medical case documents show positive results of improvements obtained with YPV healing method used by healers. Medical investigation after YPV healing confirmed that the arterial blocks disappeared after healing sessions. Conclusion: This case study documents the evidence gathered on the effective uses of YPV in healing and treating arterial blockage. To produce holistic and optimum results, YPV uses a combination of approaches such as, (1) physical exercises including rhythmic yogic breathing, (2) Salt free diet; fruit diet, (3) Meditation techniques, (4) healing by trained and experienced healers, patient participation in group healing, self-healing by patients with regular self-practice of some specified techniques. There is ample scope to conduct further research on the application of YPV as alternatively effective and low cost medicine for various medical conditions.