Background: Basis of recurring chest radiography and admission to sanatorium started at some stage in World War 2, for the prognosis of pulmonary tuberculosis in asymptomatic sufferers/soldiers of battle. Meanwhile the declining incidence of Tuberculosis and discovery of recent screening exams result in decrease in chest radiographs screening method. Chest radiographs account for majority of clinical expenditures international. Objective: The objective of this study is to determine the prevalence of chest radiographs PA view in general population of Mirpur Azad Kashmir. Methodology: This cross-sectional study was performed in District Mirpur. The data has been collected from patients at radiology department of DHQ Hospital Mirpur. The study duration was three months after the approval of supervisors. Total 180 patients participated in this study. This included males and females. Convenient sampling technique was used for the collection of data during October 2021-December 2021. Conclusion: In our study mostly patients came with symptoms if cough and according to radiographic findings must patient have cardiomegaly. It is concluded that all patients with the symptoms of SOB ,cough and fever must not have chest infection there could be another cause of these symptoms .Most patients were with cardiomegaly so prevalence if cardiomegaly is higher than chest infections like TB and other infections.

This work is aimed at formulating a polynomial function for the nonlinear analysis of CCCS isotropic rectangular thin plate. The previous researchers used trigonometry function as their shape function on the decoupled Von Karman’s equations to obtain particular stress and displacement function respectively. Trigonometry function can only be used effectively for SSSS and CCCC plates; apart from these boundaries conditions its efficiency reduces. This present work hence used a polynomial function to formulate the approximate shape function for the CCCS plate. Direct variational calculus was used applied on Von Karman’s equations to obtain the general form of minimized total potential energy which serves as a platform for the determination of coefficient factor( Amplitude or coefficient of deflection). The numerical values of CCCS plate under unit load were obtained using Amplitude equation formulated. These values were obtained for various aspect ratio (ranging from 1 to 1.5 with an increment of 0.1). This work was compared with the previous work [1] and the percentage difference in the results are within the acceptable limit. This results indicate that the approach adopted by the present work is adequate, reliable and satisfactory for the analysis of CCCS rectangular plate.

Guaifenesin is an expectorant and belongs to BCS class I which exhibits high solubility and high permeability. Guaifenesin has a half-life of 1 hour; in order to increase its duration of action gastroretentive tablets are formulated. Guaifenesin shows poor flow properties so the method opted for the preparation of this tablets is Top spray granulation. In which HPMC K100LV/HPMC E6LV/HPMC K100M/HPMC K15MPCR is used as swelling matrix polymer, Povidone is used as binder, Magnesium stearate is used as lubricant and MCC is used as diluent. Tablets are evaluated for floating lag time, total floating time, thickness, hardness, friability and invitro drug release studies were performed. The optimized formulation showed less floating lag time, sufficient floating time and with maximum drug release of 88.9% at the end of 12 hours.

Background: Studies from Rivers State have demonstrated high burden of drug resistance among pulmonary tuberculosis (PTB) patients and declining cure rate despite adequate treatment retention and highly effective directly observed treatment short-course. Aim: to explore the perception of clients on how PTB disease or its treatment affect their health (health-related quality of life), which could impact on TB treatment success rate among clients with PTB. Methods: A total of 225 adult clients with PTB were recruited by systematic random sampling method from each of the 8 randomly selected centers out of 40 active treatment centers in Obio/Akpor LGA of Rivers State. The SF 36 was used to collect responses which were grouped into 8 domains yielding 2 summary measures. Scores ≤49 were classified as poor, 50-74 relatively favourable and good for scores ≥75. Categorical data were presented as frequencies and proportions using tables and pie charts while quantitative data were presented as means and standard deviations. Results: Specific domains mean scores ranged from 34.9±33.7 (role physical) to 61.8±11.9 (general health) while physical component summary (PCS) and mental component summary (MCS) recorded 53.35±16.79 and 51.11±12.26 respectively. The overall HRQoL mean score for the study was 55.2 (± 3.6) with an undesirable score of 20.7%. Conclusion: Pulmonary tuberculosis patients in treatment centers in Obio / Akpor LGA had poor to relatively favourable HRQoL mean scores. Strengthening counselling practice may help improve support for the clients in coping with the disease and the effect of its treatment.

Different efforts have been made especially in the fields of nanotechnology that employed various combinations of nanoparticles to overcome the stresses occurred in the agricultural lands. Nanoparticles that potentially designed through nanotechnology applied to the soil in the form nanofertilizers that increased the yield also good impact on soil composition. Application of nano-SiO2 improves also seed germination throiugh rooting applications, chlorophyll content with proline accumulation. Soil composition also improved the overall fruits and vegetables varieties in such a way that nanoparticles makes intact combinations with inner layers of soil. Biological applications of iron sulfate (FeSO4) in the form of foliar spray also showed excellent resistance to the salinity stress tolerance in the case of sunflower cultivars. Nano zeolite; another type of newly modified materials efficient for long term delivery of nutrients and minerals in soil composition and mineral balance ensures for plant growth. Nanopesticides can be used for efficient crop protection also promote plant stress tolerance and soil enhancement. Nano-Si that improves the various other stresses in plants species such as nickle and chromium. Nanotechnology has several advantages over other technologies due to cost efficient and simple to use and imply on more effective treatment and remediation methods.

Aim and Objective: To evaluate the probiotic potenties along with safety of probiotics within infant faecal origin. Methods and Results: The present study isolates lactic acid bacteria from infant feces were characterized and identified by 16S rRNA sequencing. On evaluation of in vitro probiotic capability, the test isolates exhibited in vitro probiotic potency, antagonistic property and better cell surface properties. The Bile salt hydrolase activity, cholesterol assimilation, antioxidant activity and angiotensin converting enzyme inhibitory action of the test isolates proves their health conferring potency. Standard protocols were used for the estimation of lymphocyte proliferation rate, phagocytosis rate, cytokine response and faecal enzyme levels. Animal experiment using different doses of L. plantarum (MBTU-S1B) substantiated its immunotolerance against inhibitory effects of supraoptimal concentration of both T and B cell mitogens with significant reduction on β-Glucosidase and Nitroreductase activity with p< 0.05, while contrasting effect was noticed for β-Glucuronidase. Findings of the in vivo study proved higher dose of probiotic would not provide any additional benefit on host body. Conclusions: The test isolates possesed in vitro probiotic potency and the in vivo study with MBTU- S1B proved their applicability in nutraceutical and pharmaceutical industries. Significance and Impact of Study: To conflict disease outbreaks by improving general immunity via probiotics.

Moringa oleifera leaves and Ginger crops still remain an underutilized commodity because of limited information on its wider use. Moringa oleifera is very rich in nutrition but has undesirable taste and flavor. However, addition of ginger takes the edge off the bitter spinachy taste of Moringa oleifera leaves. Lactic acid bacteria (LAB) are important microbes that have long been used in both traditional and modern industrial food fermentation. Lactic acid bacteria can be used for production of food due to their ability to coax microorganisms into producing In the process of food fermentation; microorganisms produce enzymes to break down complex compounds to simple bio-molecules for several biological activities such as proteinase, amylase, mannase, cellulase, and catalase. The aim of this research work is to determine the effect of Lactic acid bacteria (LAB) fermentation on the quality attributes of tea-like beverage produced from blends of Moringa oleifera leaves and Ginger(Zingiber officinale). The results showed that The phenotypic and biochemical characteristic of Blends of Drumstick leaves (Moringa oleifera) and Ginger (Zingiber officinale) reveals that the isolates were presumptively categorized to belong to the genus Lactobacillus, the isolates are gram positive, cocci, rod shaped, either, short rod or long rods, non-sporulating, ferments carbohydrate, non-motile and catalase negative. Technological properties of isolates are the properties that indicate the quality of the isolate to be used as a starter culture in the course of fermentation. A total of 35 colonies were isolated from the blend samples. Of them, 3 colonies were identified as Lactobacillus species, through observation of phenotypic characters, and identification, It was found that L. plantarum had tolerance under acid conditions, as its viable cell count remained at pH 2.0 and under 1.0 % bile salt condition, after 72 h incubation time. The proximate and energy content of fermented beverage produced from the blends shows that percent Dry matter, Moisture content, Crude protein, Ether extract , Crude fibre, Ash, carbohydrate and energy value were ranged from 10.00- 30.00, 4.0-5.0, 35.00 -71.00, 3.0-5.0, 11.00 - 18.00,3.0-10,7.0-15 and 74Kcal - 396Kcal respectively. The study concludes that The phenotypic and biochemical characteristic of blends of drum stick leaves (Moringa oleifera) and Ginger (Zingiber officinale) reveals that the isolates were to belong to the genus Lactobacillus. Also, Many of the LAB metabolites such as low molecular weight acids, alcohols, carbon dioxide, diacetyl and hydrogen peroxides have broad spectrum antimicrobial activity against other species of bacteria. The proximate and energy value of the beverage plays a crucial role in assessing its nutritional significance (P<0.05). Consequently, the fermentation of these blends with LAB species might provide a means of retaining more of the nutrients that are trapped in the matrix of the cells of these plant materials.

The aim of this study is to evaluate the estrogenic effects of the methanolic extract of the stem bark of Cylicodiscus gabunensis in the female rat. The evaluation focused on the effect of the extract on the oestrous cycle, the evolution of the fresh weight of the uterus and ovaries, the total cholesterol level, and the total protein and oestradiol levels. The doses of extract administered to the female rats were 100, 200 and 400 mg/kg for 28 days. Administration of C. gabunensis extract at 400 mg/kg induced an increase in total protein levels. The administration of the extract at doses of 100 and 200 mg/kg gives the same results as the negative control which is distilled water. No significant variation of the C. gabunensis extract on the other parameters studied was observed compared to the negative control. This study shows that C. gabunensis would have anti-estrogenic effects, additional work should be carried out in order to validate the use of this extract in the treatment of female infertility.

This article aims to analyze the research trend and hotspots in the field of comparative literature by using the method of bibliometrics. The data is derived from the Web of Science Core Collection Database. The visualization software VOSViewer is utilized to draw keyword co-occurrence knowledge graph. R programming language is employed to analyze the quantity of publications, core journals, highly cited papers, the most contributing authors, and keyword word cloud. The results indicate that ever since 1975, this study field has entered a period of rapid development; top journals with most publications are mainly from France, the United States, the United Kingdom and Canada. Most of the highly cited articles have emerged in the recent two decades, and quite a few of them inherit the academic tradition of adopting a geographic perspective. The keyword word cloud and the keyword co-ocurrence knowledge mapping reveal that comparative literature study is shifting its focus from literary history and intertextuality to identity, culture, literary theory and world literature. The recent reserch hotspots in this field are mainly identity, culture, world literature, literary theory, Latin American literature, appropriation, genre, theatre, ethics and digital humanities, etc.

Introduction: Preterm labor is one of the clinical events that can change a normal pregnancy into a high-risk one for both the mother and the fetus. Preterm labors are thought to be caused by a combination of factors, including decidual bleeding and uterine deformation. Aim of the Study: The aim of the study was to observe the maternal complications of preterm birth. Methods: This cross-sectional study was conducted at the Department of Obstetrics and Gynecology, Chittagong Medical College Hospital, Bangladesh. The study duration was 6 months, from January to June of 2015. Purposive sampling method was used to select a total of 100 women from those admitted at the study hospital for deliveries according to inclusion and exclusion criteria. Result: Most of the patients were from the third decade of life. Majority (61.0%) patients had multi para. Majority (39.0%) patients were gestational age 34 weeks. More than half (53.0%) had infection, among which urinary tract infection were the most common. Neonatal death was 61%, and most common cause of neonatal death was septicemia, followed by respiratory distress syndrome. Conclusion: Most of the patients were in 3rd decade of life, and did not receive regular antenatal check-up. Infection and pre-eclampsia were the most common maternal complications, while respiratory distress syndrome was the most common perinatal morbidity. Septicemia and respiratory distress syndrome were the most common cause of perinatal death.

Background: Worldwide, head and neck cancer (HNC) was the 6th most common cancer in 2020 in all ages and both sexes. In Bangladesh, lip and oral cavity cancer was the 2nd most common cancer in 2020. Up to 60% of HNC patients presents with locally advanced disease. Aim and Objective: To determine treatment Interruption and hospital admission in head and neck cancer patients during concurrent chemoradiotherapy with or without prophylactic nasogastric tube feeding. Materials and Method: A quasi-experimental study was performed in Radiation Oncology Department of National Institute of Cancer Research & Hospital from 1st January 2020 to 31st December 2020. A total number of 68 Patients (34 patients in each arm) was included in this study according to inclusion and exclusion criteria by purposive Sampling technique. All patients in Arm A and Arm B were planned for total 66 Gray in 33 daily fractions, 2 Gray per fraction, 1 fraction per day, 5 fractions per week over 6½ weeks and inj. Cisplatin 40mg/m² was given intravenously 2 hours before radiotherapy on 1st day and then weekly. All the information’s were recorded in a pre-tested and semi-structured questionnaire. The analysis was done by using independent sample t test for continuous variables and chi-square test for categorical variables and data were presented in tables and graphs. Results: In this study, mean age was 52.5 ± 8.5 years and male: female ratio was 4.2: 1 among all patients. The Incidence of treatment interruption was significantly lower in Arm A compared with Arm B (29.4% in Arm A and 70.6% in Arm B, p-value < 0.05). There were fewer patients who required hospitalization in Arm A (23.5% in Arm A and 55.9% in Arm B) and length of hospital stay was less too (5.3 ± 1.7 in Arm A and 10.0 ± 1.9 in Arm B, p value <0.05). There were no significant differences in treatment response and toxicities between the two groups. Conclusion: Prophylactic nasogastric tube feeding at the beginning of CCRT in head and cancer patients is beneficial in terms of preventing treatment break and reducing hospital admission.

The antiquity of the Federal Republic of Nigeria is replete with the search for effective and efficient models of governance to aid harmonious co-existence among the federating units. This has unfortunately led to an unending discussion on constitutional restructuring. The Legal framework and the institutions charged with the responsibilities of developing these models is and are established by the 1999 Constitution of the Federal Republic of Nigeria (as amended). Nigeria is increasingly becoming a theatre of war and terrorism centre where human life is not valued. Nigeria is stressed and distressed, with ‘revolutionary pressures’ everywhere. How did we get to this gridlock? How do we get out of it? And where do we go from here? Why is a country that was once ranked with India, Malaysia, Singapore, and South Korea still moving in circles instead of moving up? Why are we still a country in transition, more than a century after the Amalgamation? Are we fated to be a banana republic? This paper is to examine, cross-examine and re-examine these and other questions. It is the view of the researchers that all though the 1999 Constitution of the Federal Republic of Nigeria (as amended) is not a perfect document, the major problem is that those saddled with the responsibility of implementing the provisions of the constitution are allowing the primordial sentiments of ethnicity and religious inclinations to becloud their sense of patriotism and nationhood, hence the constitution is implemented more in breach and default. There is therefore the need for a mental re-orientation and national re-birth to forge a greater sense of unity among the diverse ethnic groups that make up the Nigerian nation. The paper concludes by suggesting for the rapid mental renovation of political office holders and all citizens to embrace the rule of law where justice, fairness, and equity will regulate human conduct. This will ultimately metamorphosed into building a strong institution rather than strong personalities in Nigeria. The researchers ultimately advocates for sincere implementation of the provisions of the constitution as it is, pending constitutional amendment. The research methodology utilized by the researchers is the Qualitative Research methodology.

This present paper deals with large deflection of clamped thin rectangular isotropic plate under uniformly distributed load. The analysis of clamped plates is of great important and its structural behavior has not been completely understood. Previous studies have made a great in road in the analysis of clamped plates through varied approaches mostly assuming trigonometric series as displacement field. A variational method based on the principle of minimization of total potential energy has been employed through assumed displacement field. Therefore, the von Karman differential equation was decoupled through direct integration retaining its non-linear character. The aim of this present studies is to provide solution to analysis structural behavior of clamped (CCCC) thin rectangular isotropic plate under uniform distributed. The analysis was accomplished through a theoretical formulation of shape function based on polynomial series and subsequently, the formulated shape function was used on Ritz energy method. The resulting functional was minimized to obtain a general amplitude equation of the form K1∆3+K2∆+K3. Where K1, K2 and K3 are coefficients of amplitude equation and ∆ is the deflection coefficient (factor). Newton-Raphson method was used to evaluate the deflection coefficient. Values of ∆ from Timoshenko and that from present study were compared with an aspect ratios ranging from 1.0 to 1.5 with an increment of 0.1. From results obtained, the average percentage difference for the pervious and present studies is 3.7646%, The percentage difference for the plate was within acceptable limit of 0.05 or 5% level of significance in statistics. It is shown from the comparison that good agreement exists between the present and previous works and that this approach provides simply, direct, straightforward and highly accurate solutions for this family of problems.

The Liquid-Liquid equilibria of Tertiary-Butyl Alcohol – Water – Benzene System were measured experimentally at 30°C and 1atm pressure. The experimental binodal curve compositions were obtained using the cloud point method. The compositions of the two equilibrium phases were analysed using Agilent 7820A series Gas Chromatograph. The consistency of the experimental data was determined using the Hand, Othmer-Tobias and Bachman- Brown correlation equations while the plate point was determined using the Treybal’s method. The effectiveness of the solvent in the extraction was determined by calculating the distribution coefficients and separation factors. The experimental tie-line data were correlated with the Universal Quasi-Chemical (UNIQUAC) and Non-Random Two Liquid (NRTL) activity coefficient models. Also, the deviation between the experimental and calculated equilibrium compositions were calculated using the root mean squared deviation equation. The UNIQUAC predicted data gave a closer resemblance to the experimental.

This study this study therefore examines guessing parameters and 2016 and 2017 NECO Mathematics multiple choice test items in Calabar education zone. The research objectives specifically compared the guessing parameter of the 2016 and 2017 NECO Mathematics multiple-choice test items; and also, compared the measurement theories and year of examination on reliability coefficient of 2016 and 2017 NECO Mathematics multiple-choice test items in Calabar education zone, Cross River State. To guide the study two research questions and hypotheses were further formulated and tested at 0.05 level of significance. The instrumentation research design was adopted for the study. One thousand three hundred and fifty-one (1,351) students were selected using the stratified random sampling procedure. Two instruments, namely the 2016 and 2017 NECO mathematics multiple choice tests were used for data collection. Using ANOVA and correlated t-test to analyze data collected from the field, the result reveals that guessing parameter and reliability indices of the 2016 and 2017 NECO mathematics multiple choice tests were significantly different. It was concluded that guessing parameters differed significantly with the years of study and also, there was a significant influence of measurement theory and year of test on item reliability on NECO mathematics examination papers significant difference exists between psychometric properties using the different measurement theories. Based on these findings, it was recommended that NECO should use the item response theory (IRT) in assessment for its relative merit over the CTT.