Background: Hyponatremia, which is defined as plasma sodium concentration of less than 135meq/L, occurs primarily due to imbalance in water homeostasis, antidiuretic hormone (ADH) regulation and renal handling of filtered sodium. The two most common causes are effective circulating volume depletion causing non-osmotic release of ADH and the syndrome of inappropriate ADH secretion, disorders in which ADH secretion is not suppressed despite decrease in plasma osmolality. Methods: Observational Study conducted at Medicine wards and, Medicine OPD of SMS hospital, Jaipur. Patients were interviewed for demographic data such as age and sex. History of other comorbid conditions along with presenting complaints was noted. Further these patients were subjected to a physical examination for clinical signs. These findings were recorded on a predesigned and pretested proforma. Results: In our study, lethargy(50.4%), headache(42.3%) and anxiety(31.7%) were most common symptoms. Majority of the cases were admitted and treated in the ward i.e. 249(87.7%), while few patients were treated in ICU i.e.35 (12.3%). Conclusion: Based on the findings of this study it may be concluded that, hyponatremia can present with protean clinical manifestations. The presentation can vary from mild symptoms such as vomiting, lethargy, malaise to severe forms such as confusion, seizure and coma.