This study was carried out to investigate the antioxidant and serum lipid effects of the leaf extract of Momordica charantia on male wistar rats. The animals were divided into three (3) groups of six (6) rats each. Group one (1) served as control and received distilled water. Group two (2) and group three (3) were treated with 200mg/kg bw and 400mg/kg bw of the hydromethanol extract respectively. Extract was orally administered once daily for 30 days. The results obtained showed that the extract caused a significant increase in the catalase and gluthathione enzyme activity and a significant reduction of malondialdehyde level. There were no significant alterations of low density lipoprotein cholesterol (LDL-c), high density lipoprotein cholesterol (HDL-c), triglyceride and total cholesterol concentrations. The lipid ratios like the Castelli’s Risk Index I and II were not affected. This study showed that, the leaf extract of Momordica charantia demonstrated anti-oxidant effects but did not influence risk ratios for developing cardiovascular diseases in wistar rats.

Systemic diseases hold major importance in relation to the prosthetic restorations supported by the dental implants in medically compromised patients. It is essential to monitor each stage of the treatment from beginning of the treatment plan to the long term follow-up it is under thereby a necessity of the interdisciplinary approach to the underlying disorder.

Background: The population of persons living with diabetes and hypertension is increasing worldwide. Despite this increment, data on this subgroup of patients is scarce. Objective: To study the socio-demographic, clinical and biochemical characteristics of patients living with type 2 diabetes and hypertension co-morbidity. Subject and methods: This is a cross-sectional study carried out at the cardiology unit of the department of Internal Medicine University of Portharcourt Teaching Hospital. One hundred and sixty adults18years and above living with hypertension and diabetes were recruited. 80 adults living with hypertension matched for age and sex served as control. Data on patient’s age, sex, duration of hypertension, DM, family history of diabetes , hypertension, history of sedentary life style, alcohol consumption, peripheral neuropathy, smoking and ischemic heart disease, body mass index, waist circumference, blood pressure ,pulse pressure, fasting blood sugar, fasting lipid profile and serum electrolyte ,urea and creatinine were obtained. Results: The mean age of the cases was 57.51±9.1 years. There were 60% females and 40% males among the cases. Family history of DM and hypertension were found in 81(50.6%) and 107 (66.9%) respectively. History of ischemic heart disease was positive in 63(39.4%) of the cases and positive in 40(50%) of the controls. The mean body mass index was statistically higher in the cases compared to the controls (29.46±4.4kg/m2 vs 26.66±4.40kg/m2 p=0.022). The prevalence of sedentary life style was significantly higher in the cases than the controls 58(36.2%) vs 19(23.8%)p=0.001). The systolic BP and triglyceride of the cases and control were comparable. Mean e-EGFR was significantly lower in the cases than the controls 68.98±25.14mls/min vs 88.33±28.94ml/min. Conclusion: Sedentary lifestyle, obesity and renal impairment were common in people living with hypertension diabetes co-morbidity. Ischemic heart disease based on history was less common.

Background: We evaluated the predictive power of the C-reactive protein (CRP)/albumin ratio for intraparenchymal injury and the severity thereof in patients with head trauma. Methods: One hundred and seventy-five consecutive adult patients with head trauma admitted to our tertiary care emergency department from January to December 2017 were included in this retrospective study. The patients were divided into the following two groups: those without (group 1) and with (group 2) pathological findings related to head trauma on cranial computed tomography (CCT). The patients were also divided into two subgroups based on the presence or absence of traumatic parenchymal lesions (e.g., brain swelling, cerebral contusion, intracerebral hematoma, and pneumocephalus, defined as traumatic brain injury (TBI). Observations and Results: CCT revealed that 124 (70.8%) patients had pathological findings (CCT+), of which skull fracture was the most common (n = 50 patients). Compared to head trauma patients without pathological lesions on CCT (group 2), the mean serum CRP/albumin ratio was significantly elevated in patients with pathological lesions (group 1). Of the 175 patients, 104 (59.4%) exhibited trauma-related parenchymal lesions on CCT. Compared to head trauma patients without TBI, the mean serum CRP/albumin ratio was markedly elevated in patients with TBI. Conclusions: An increase in the serum CRP/albumin ratio in patients with TBI enables discrimination of those with and without pathological lesions on CCT. The CRP/albumin ratio might be predictive of trauma-related parenchymal lesions in patients with head trauma.

Internal hernias represent less than 1% of the causes of acute intestinal occlusions of mechanical origin, they can be acquired or congenital, among these hernias, an internal hernia of appendiceal origin has never been reported, we report the case of a patient who presented acute apendicitis complicated with strangulated internal hernia.

Respiratory infections are quiet common in today’s world. Endemics ad Pandemics like SARS and Corona Virus infections has made headlines already. Especially in the urban or semi developed areas the people more prone to such conditions. This study puts in an effort to find pathological complications of Upper respiratory tract.

The street play based learning is becoming more popular to support learning process of students in professional colleges by asking students to understand the basis of clinics and also the attitude and behavioural learning using a street play which the students will display to other students. Bed side clinics are the gold standard but as the number of colleges is increasing the number of patients is slowly decreasing. It is practically impossible to show all the cases to the learning students. But there is a way and it is in this way that the professional actors or the doctors themselves who has knowledge of the disease can enact and thus teach the students. This study puts in a sincere effort to find the answer of which method is better.

Tuberculosis is one of the dreaded infections which are commonly found in our country. In fact there is a saying that if none of the medicines wok and the patients is still ill then there is a high chance of the patient suffering from tuberculosis in India. Vitamin D has been observed to be low and has been always understood to have an influence in the patient’s outcome also. There is no base line study done to understand the involvement of the Vit D in the patients. So this study is one such novel effort to understand the same.

Acute respiratory infections are one of the causes of morbidity and mortality in our country. The present study was undertaken to study the complications of lower respiratory tract infection.

Facial perception is the first aspect to recognize and understand a person. Thereby, for these reasons, the face has always been significant historically. Moreover, mouth significantly affects the appearance of face. Several people regularly make serious requests to the dentists in order to meet their aesthetic demands, like some of the people pay less attention to the health of their posterior teeth, but they do give attention on the anterior tooth decay, or their malformation and want them to be treated as early as possible. Since the facial region contributes to the self esteem and self respect of an individual both positively and negatively which leads to the prime motivation towards having a beautiful and attractive face. A pleasant face makes people to feel better and also impart positive effects on the social relationships.

Implant treatment is regarded as a safe technique with high rates of success. Nevertheless, it has, as every surgical procedure, several complications that can occur and that must be known in order to prevent or solve them. Implant surgery complications are frequent occurrences in dental practice and knowledge in the management of these cases is essential. While dental implants are increasingly becoming the choice of replacement for missing teeth, the impediments associated with them are progressively emerging too. The aim of this review was to highlight the challenges of treatment plan-related, anatomy related and procedure-related surgical complications as well as to discuss the etiology, management and treatment options to achieve a satisfactory treatment outcome.

Latex allergy is an occupational hazard in healthcare workers. This review is aimed at highlighting reaction types, clinical presentation, diagnosis, and management of latex allergy in healthcare workers (HCWs).

Aim: To investigate the retinal nerve fiber layer (RNFL) thickness in patients with Alzheimer disease (AD) without visual impairment using optical coherence tomography (OCT) and to compare the results with healthy control. Study Design: Case Control, Quantities, non-randomized study. Methods and materials: This study was conducted in the neurology and ophthalmology department, King Faisal Specialized hospital, Riyadh, Saudi Arabia from January 2015 to April 2015. Sample: This study was included 22 participants, 11 Alzheimer's patients and 11 healthy controls between the age of 50-75 years old female and male. Examinations: After sinning the informed consent, a number of examinations in the ophthalmology performed and the retinal nerve fiber layer thickness was measured by 3D OCT-2000 Spectral Domain OCT. Statistical Analysis: All statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS), version 21.0, for MacBook Pro. Data were expressed as mean ± standard deviation. All the data were analyzed and compared using Mann–Whitney U test. A P-value ≤ 0.05 was considered to indicate statistical significance. Results: Patients with AD showed a significant reduction in the total RNFLT compared to the control group (84.21 ± 12.68 μm versus 98.27 ± 16.25 μm; P = 0.006). Furthermore, the nasal and inferior RNFL thickness were significantly lower in patients with AD compared to the controls with a P = 0.007 and P = 0.010 in the nasal and the inferior quadrant, respectively. Also, no significant thinning in the temporal and the superior quadrant in AD retinal nerve fiber layer was detected. Conclusion: Patients with Alzheimer disease exhibit a thinner retinal nerve fiber layer (RNFL) than the healthy control subjects.

Purpose and objectives: Decrease in length of Post-Anesthesia Care Unit (PACU) recovery time has been linked to both patient satisfaction and reduced healthcare cost. This was a quality project which retrospectively reviewed patients` chart to assess recovery time whether administration of co-analgesics and sedatives in combination with propofol prolong recovery time. Primary outcome: PACU recovery time using the modified Aldrete scoring system. The ideal anesthetic for ambulatory cases should provide rapid and smooth emergence and recovery. Propofol is recently preferred short acting agent for gastrointestinal endoscopic procedures for induction, maintenance of anesthesia/deep sedation (1). The randomized controlled trials indicated that the potential benefits of propofol include a shorter recovery time, greater sedation, and improved patient cooperation (2). However, high dose of propofol may cause side effects and delay emergence. Study Design: This was a quality project which was retrospectively evaluating consecutive Gastroendoscopy cases at Parkland Hospital. Eligible subjects who received esophagogastroduodenoscopy (EGD) in 1 years’ period between 2014 to 2015. All patients in the review received propofol as their primary anesthetic, while some received additional co-analgesics and sedatives (midazolam, fentanyl, etomidate, ketamine, diphenhydramine). Recovery and PACU discharge time were compared between the propofol only groups versus the propofol plus adjuvant drug based on the modified Aldrete scoring system. Data was electronically collected in encrypted and password protected Excel file. At the end of the data collection, this Excel file was de-identified for the data analysis. Data was stored in secure encrypted research computer or secure research server and only research team will have access to electronic files. Retrospective analysis of consecutive patients undergoing esophagogastroduodenoscopy (EGD) at Parkland Hospital. The consecutive cases were evaluated for the Postoperative recovery time. The sample size of the project is the expected number of patients underwent EGD during 2014 to 2015.