Acromegaly is a condition caused by an excessive secretion of growth hormone due to a somatotropic pituitary adenoma, leading to an acquired dysmorphic syndrome. The aim of this study is to evaluate the effectiveness and tolerance of medical treatment using Lanreotide LP 120 mg in 15 patients with acromegaly, who were followed up at the endocrinology department of Ibn Sina Hospital in Rabat between 2017 and 2018. The quality of life of the patients after Lanreotide treatment was evaluated using the AcroQol questionnaire. 80% of the patients were found to have acrofacial dysmorphic syndrome, with the diagnosis based on clinical, biological, and radiological data. Magnetic resonance imaging revealed a pituitary macroadenoma in 86.7% of the cases. All patients were treated with medical treatment using Lanreotide LP 120mg. Fourteen patients underwent adenomectomy, with 4 of them receiving GammaKnife radiotherapy. During treatment, complications were observed in 80% of patients, with half of them related to vesicular lithiasis. The AcroQol scores obtained in the study were less satisfactory than expected, indicating a lower quality of life compared to the general population.

A case of carpal tunnel syndrome was incidentally discovered during an occupational pathology consultation in a 51-year-old class teacher, with more than 24 years of service, presenting with tingling and tingling in the right hand and pain radiating to fingers and forearm. The use of chalk on the blackboard and the pen on paper constituted the professional causes found. The symptomatology was exacerbated after each working day, calmed down during weekends and holidays, and awoke to rare domestic work such as (washing linen, sifting flour, etc.). The patient, after numerous consultations in traumatology for joint pain in the wrist, was also followed by another doctor for arterial hypertension. The result of the first ultrasound was contradictory to the clinic, concluding with De Quervain's tendonitis. The CT scan of the wrist did not provide any evidence for the diagnosis. The requested electromyogram was not made available. The infiltration of corticosteroids helped to calm the pain and the associated signs.

Taurine chemically known as 2 aminoethanesulfonic acid; NH2CH2CH2SO3H it’s a non essential amino acid, due to absence of carboxyl group it does not participate in protein synthesis, it does not metabolized and thus not involved in gluconeogenesis, thereby not constituting a direct energy source, This wonderful molecule was discover in 1827 by two German scientist Tiedemann and Gmelin from bile of ox (Bos taurus), Ten years later, this amino acid got its name as Taurine by Demarcay, and 20 years later Jacobsen and Smith discovered that its structure contains sulfur. In a wide variety of invertebrate and vertebrate tissues the natural occurrence of taurine has been recognized, It is also present in plants algae and fungi. In this review we try to cover all possible beneficial role of taurine.

This review article examines the importance of postoperative management and follow-up for individuals who undergo bariatric surgery. The study covers various aspects of postoperative care, including patient selection and preparation, nutritional management, physical activity, monitoring and follow-up, and psychosocial support. The article provides recommendations for each aspect and discusses the factors that influence weight loss outcomes after bariatric surgery. Strategies for addressing psychological and emotional challenges are also explored, along with the role of support networks in achieving long-term success. The findings suggest that a comprehensive approach to postoperative care, including regular monitoring and follow-up, nutritional management, physical activity, and psychosocial support, is crucial for achieving optimal weight loss outcomes after bariatric surgery. The study has important implications for clinical practice, and future research should focus on identifying ways to improve postoperative care and outcomes for individuals who undergo bariatric surgery.

We present thirteen examples of pulmonary pneumocystis (PCP) in patients without HIV infection. Eight men and five women, average age 55, with one instance of breast neoplasia, two cases of DICV, one case of "Goodpasture's syndrome," one case of idiopathic fibrosing PINS treated with extended corticotherapy for two years, and the other patient without known immunosuppression. In 11 cases, there is persistent dyspnea and severe hypoxia. Lymphopenia (9 instances), with a 920.76 element/mm3 average rate. Except in two cases where examination of the bronchoalveolar lavage fluid was required, the diagnosis was established by the isolation of Pneumocystis jiroveci in the induced sputum. The evolution was positive in every case while receiving trimethoprine-sulfametaxazole and corticosteroid therapy.

Nonketotic hyperglycemia is a rare cause of hemichorea-hemiballismus. We report a case hemichorea-hemiballismus secondary to nonketotic hyperglycemia revealing an inaugural diabetes mellitus. A 55 year-old woman, admitted for subacute-onset of continuous involuntary movements in the right upper and lower limb since three days ago. The movements increased with action, decreased with relaxation, and disappeared during sleep. As the condition did not affect her trunk, other limbs, or her face and no other conditions were evident. At admission, the right upper and lower limb was moving involuntarily. The movement was wild, flailing, and repetitive with varied amplitudes and frequencies. No tremor and rigidity were elucidated and cerebellar signs were negative. Laboratory tests revealed diabetes mellitus, with a fasting blood glucose level of 4,60 g/L and a hemoglobin A1C level of 14.0%. The urine examination was negative for ketones. CT of the brain showed left pallidum hyperdensity. The brain MRI revealed hyperintense signal in the left pallidum on T1-weighted images and isointensity on T2-weighted images. Other laboratory results were within the normal range. A diagnosis of hyperglycemia-associated hemichorea-hemiballismus was made. An insulin treatment and oral antidiabetics were instored. She was subsequently discharged after 14 days of hospital stay with improved glycemic control. Three months after, her chorea-ballismus was completely resolved. A control of brain MRI six month after showed marked improvement in the putaminal changes. Vigilance for this cause of hemichorea-hemiballism is important, since the movement disorder may be the presentation of potentially dangerous underlying hyperglycemia.

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a rare congenital disorder that affects the female reproductive system, resulting in uterovaginal agenesis. It’s typically presented as primary amenorrhoea in adolescence in female with normal development of secondary sexual characteristics and 46, XX karyotype. In this article, we report an unusual case of MRKHS of a girl of 7 years old who consulted for premature thelarche & pubarche. She has a normal karyotype (46, XX) with normal external genetalia. Gonadotropin releasing hormone (GnRH) stimulation test revealed a peak LH level of 1.77 UI/l and peak FSH level of 5.44 UI/l. Imaging disclosed advanced bone age at 10 years. Pelvic MRI showed uterine hypoplasia with partial vaginal agenesis.

Background: Chronic kidney disease (CKD) is a non-communicable disease that includes a range of different physiological disorders that are associated with abnormal renal function and progressive decline in the glomerular filtration rate (GFR). Chronic kidney disease (CKD) is the 16th leading cause of years of life lost worldwide. Like other developing countries, the prevalence of chronic disease is increasing trends in Bangladesh. Prior conception regarding the socio-demographic status of patients with chronic kidney diseases may be helpful for respective health professionals and researchers. Aim of the study: This study aimed to evaluate the socio-demographic status of patients with chronic kidney diseases. Methods: This was a descriptive cross-sectional study that was conducted in the Department of Medicine and Nephrology, Dhaka Medical College & Hospital (DMCH), Dhaka, Bangladesh during the period from January March 2018 to September 2020. A total of 150 diagnosed cases of CKD were enrolled in this study as a study population. Properly written consent was taken from all the participants before data collection. All data were processed, analyzed, and disseminated by using MS Excel and SPSS version 23.0 program as per necessity. Results: In this study, male participants were dominant in number and the male-female ratio was 1.7:1. The mean age of the respondents was 53.31±10.28 years. The highest number of our participants were unemployed 65(43.3%) and the majority of our respondents 106(70.7%) were married. Among the total participants 83(55.3%) patients were with hypermagnesemia whereas 10(6.7%) with hypomagnesemia. In this current study, among the total respondents 51(34%) had CKD stage 5, 42(28%) had CKD stage 4, 38(25.3%) had CKD stage 3, 14(9.4%) had CKD stage 2 and only 5(3.3%) had CKD stage 1. Conclusion: As per the findings of this study, we can conclude that male people are prone to chronic kidney diseases (CKD). Early investigation and proper treatment can decrease the occurrence of CKD as well as the mortality and morbidity of such theses.

Background: Cataract is a common cause of visual impairment in the elderly and the leading cause of blindness worldwide. Bangladesh is not exception of this. Though cataract treatment is available across the country but there is no nationwide strategy to prevent this disease. Therefore, this study tried to explore the distribution of this diseases among the elderly patients in Bangladesh to provide some insights about the prevention strategies of cataract. Methodology: This descriptive cross-sectional study was conducted among conveniently selected 1020 cataract patients attending in two eye camps of Bagura and Jaypurhat districts in Bangladesh. Face to face interview was taken by using a structured validated questionnaire. Descriptive statistics such as frequency, percentage, mean, median, and standard deviation as well as inferential analysis were used for both categorical and continuous variables with the application of Statistical Package for Social Sciences (SPSS) version 26. Results: Out of 1020 cataract patients, male and female were 53.5% and 46.5%, respectively where 69.5% were in the age group of 15-64 years. Approximately 50% of participants were illiterate and 70.6% had family history of cataract. About 42.8% of respondents had identified age as the cause of disease and almost 50.8% were suffered from 1.1 to 3 years. 39.4% had delayed in receiving treatment for having financial issues. Age and gender had statistical significant association (p<.05) with the cataract. Conclusion: Age and gender based prevention strategies should be planned and implemented as cataract is found to be prevalent on these variables in this study.