Aesthetics is a major concern for dental patients and is a challenge in contemporary dental rehabilitation for clinicians and dental technicians. Discolored frontal maxillary teeth can result in excessive psychological suffering for the affected individual. Here we describe the use of zirconia CAD/CAM restorative materials for the treatment of teeth in the aesthetic zone for a 26-year-old teacher. Maxillary central and lateral individual zirconia crowns were manufactured and cemented with dual-cure resin cement. Harmony with the existing shade of all teeth was achieved. The patient reported improved self-esteem and better relationship with their students as well as social interactions.

Pulmonary tuberculosis is the second most common infectious killer, claiming more than one million lives each year. The tuberculosis is common worldwide, but it is endemic in some parts of the world, such as Asia and Africa. The documented cases of endobronchial tuberculosis are less than that the magnitude of the problem because bronchoscopy and high resolution computed tomography is usually not performed in all cases of suspected or confirmed pulmonary tuberculosis. The complications and late sequelae are major challenges where infrastructure and expertise in Interventional bronchoscopy are warranted.

For management and treatment of diabetes several medicinal plants are used worldwide as well as these are being utilized customarily for the management of diabetes in human. The current study explored Stevia (Stevia rebaudiana) and gurmar (Gymnema Sylvestre) to determine their hypoglycemic activity compared to the standard drug metformin. Streptozotocin was used to induce diabetes in rats (55 mg/kg) intraperitoneal. For a time period of 60 days stevia (100mg/kg), gurmar (500mg/kg), and their combination (500mg/kg) was administered orally as well as metformin at the rate of 800μg/kg after 2 weeks of STZ injection. Hypoglycemic effects were shown best in combined stevia-gurmar extract than the individual doses of stevia and gurmar. (OGTT) oral glucose tolerance test and measurement of blood glucose levels were assessed. Reduction in body weight by STZ was also found to increase in all rats except stevia treatment. In conclusion, the extracts of stevia and gurmar showed hypoglycemic effect as well as improving body weight effects in diabetic rats. Therefore, it can be suggested that stevia as well as gurmar extracts have a potential in preventing diabetes and can be used as antidiabetics in herbal medicine.

The irruption and global spread of pandemic Covid-19 since the end of 2019 has led to a serious and a comprehensive chaos affecting almost all aspects of the life. The consequence resulted in an international concerns where the control of the pandemic went out of control by the World Health Organizations (WHO) as well as the developed countries. The pandemic looked as a biological war being launched by the giant countries USA and China particularly against the elderly people to trim down the world populations of them due to the increase the life span in the well developed countries and the increase in rate of birth in developing countries. The overall mortality has exceeded a few millions without any ironic action to stop spreading the virus nor protecting the lives. Most of the modern global measurements taken so far to overcome the crisis have failed to contain the pandemic. While all the man-made laws failed to contain the pandemic the measurements driven from the activation and application of the divine laws, represented in Islamic values e.g. faith values, could guarantee the overcome the worldwide crisis.

Introduction: Congenital heart disease (CHD) is the most common birth defect. Emotional and behavioral problems are among the most prevalent chronic health conditions of childhood and often have serious negative consequences for a child’s academic achievement and social development. Iron deficiency is one of the most common nutrient deficiencies. Aim of The Work: To determine the effect of iron deficiency and congenital heart disease on the behavior of children. Subjects and Methods: This is a case control study of 90 children, 60 children had congenital heart disease they divided into two groups: 30 cyanotic and 30 acyanotic. All studied children subjected to the following: Assessment of behavioral disturbance using an adapted Arabic translation of. Conners’ PARENT rating scale and specific laboratory investigations including: serum ferritin, serum iron, total iron binding capacity, transferrin saturation capacity. Results: Behavior disorders were more frequent among congenital heart disease patients (33, 3%) compared to controls (13.3%) regardless the type of congenital heart disease either. Iron deficiency was more prevalent among children with congenital heart disease 25 (41.6 %) in comparison to control group 4 (13.3%) specially in cyanotic heart disease as we found 43.3% had iron deficiency in comparision to cyanotic heart disease (33%) . .There was slight increase in behavioral disorder in children with iron deficiency specially in those with cyanotic heart disease. Conclusion: Children with CHD are at higher risk of behavioural disorder specially those how suffering from iron deficiency.

Radish is consumed and cultivated globally and is reflected as a part of human-diet, although this root vegetable is not common in many populations. Different varieties of radish have the different soil and climate requirements for better growth and yield but the most beneficial and important agro-technique is nutrition for better performance. For better quality and optimal radish production, fertilization by organic, inorganic and bio-fertilizers are very important constituents. Other pharmaceutical uses of radish include treatment of chronic diarrhea, neuralgic-headache and sleeplessness. Toxicity of Ni in radish plant is confirmed by inhibition of growth, chlorosis, necrosis and wilting. This report based study conducted to investigate the biological, physiological effects of heavy metals on the radish. In this study it was noticed that nickle sulphate act as suppressor on growth of the plant and it also decreased the content of carotenoids and chlorophyll contents such as Chlorophyll-a, b. Statistical analysis was achieved after collection of data by using appropriate computer software such as ANOVA.

Objective: The purpose of this study is to compare the kinematic differences of different level jumping athletes in the process of squatting on different ground, and to reveal the photomechanical mechanism of the effect of squatting on the different ground on training effect. Methods: The subjects were 11 first-class and above jumping athletes (excellent group) and 11 second-class athletes (ordinary group). The kinematic data were photographed by SONYDCRHC52E high-speed camera with a sampling frequency of 50 frames per second, and the data were analyzed by SIMI-Motion three-dimensional motion analysis system. Subjects squatted and jumped on four kinds of ground (force platform, balance pad, gymnastics pad, and sand) with their hands on their hips. Results: In the intra-group analysis, it was found that the athletes of different levels squatted and jumped on four different kinds of ground, but there was no significant difference only on the balance pad and gymnastics mat (excellent group p=0.344, ordinary group p=1). In the inter-group analysis, it was found that there were significant differences between different levels of athletes in balance pad (p=0.043) and sand (p=0.02). In the buffering stage of the squatting jump, there was no significant difference in the buffering angle displacement of lower limb joints of different athletes on different ground. In the stage of pedal and extension, the angular displacement of the ankle on the middle platform of the excellent group was significantly different from that of the balance pad (p=0.014), gymnastics pad (p=0.017), and sand (p=0.013), but in the ordinary group, the ankle angular displacement of the middle platform was only significantly different from that of the gymnastics pad (p= 0.048) and sand (p=0.017), but not significantly different from that of the balance pad (p=0.166). The maximum angular velocity of the hip joint of athletes of different levels was significantly different among different ground groups. The maximum angular velocity of the ankle joint of the common group was significantly different in force platform and sand (p=0.032), gymnastics ma,t and sand (p=0.008), but there was no significant difference in balance pad. Conclusion: Different places have a great influence on the ordinary group, and on the ground with lower elastic coefficient, the maximum angular velocity of the ankle joint in the ordinary group is much smaller than that in the excellent group, which indicates that the rapid contractile ability of ankle muscles in the ordinary group is poor on the ground with low elastic coefficient. When squatting and jumping on the ground with a lower elastic coefficient, the excellent group has better body control and coordination and lower joint energy loss, which makes the jumping effect better, while the ordinary group squats and jumps on the ground with a low elastic coefficient and unstable ground. The jumping effect is poor.

The natural healing process of skin wounds and burns is a time taking phase during which there is also risk of pathogenic invasion and to avoid this possible complication, various types of wound dressings i.e., organic, herbal and synthetic origin have been prepared and applied. Among them, recently explored dermal healing potential of collagen of wasted fish skin is getting attention. It is not only a low cost locally available form of organic waste but also exhibit antimicrobial properties. Recent data indicates that a wounded or burnt skin coated with fish skin recovers comparatively faster. Thus, further optimization is required to make pharmaceutically accessible for general public.

The development of a Web-based learning environment is time-consuming and complex. Hypermedia and interactive aspects are problem-specific and usually require a special authoring tool. This article describes how the development of hypermedia environments for computer graphics is preceded by the development of a hypermedia authoring tool. The implemented architecture is presented, which meets the requirements with regard to the inexpensive construction of a new environment, its consistent modification, its step-by-step internationalization, personalization and the integration of interactive virtual experiments and learning methods.

The knowledge of engineering properties is vital in designing postharvest equipment. In this research work, some physical and thermal properties of kariya (Hildegardia barteri) kernel were studied with respect to moisture content in the range of 8.83 to 27.42 % dry basis (d.b). The surface area, geometric mean diameter, arithmetic mean diameter, bulk density, true density, aspect ratio, sphericity, volume and porosity ranged between 154.09 and 200.29 mm2, 7.75 and 8.64 mm, 144.40 and 216.66 mm, 0.65 and 0.72 kg/m3, 1.01 and 1.29 kg/m3, 0.64 and 0.69 mm3, 12.40 and 14.59, 226.94 and 340.23 cm3 and 40.28 and 98.46, respectively. The static coefficient of friction ranged from 0.42 and 0.53; 0.40 and 0.51; 0.42 and 0.52 for galvanized steel, stainless steel and glass surface respectively. Thermal properties were found to increase from 0.17 to 0.51 kJ/kgK, 1.2 to 2.0 x 10-7m2/s and 1.43 to 2.73 W/moC, for specific heat, thermal diffusivity and thermal conductivity respectively. Models were established for all the parameters measured for the kariya kernel as a function of moisture content, with high correlation coefficients. These models can adequately predict the properties within the moisture range examined.

The tourism object with the greatest potential to be developed in Tanah Laut Regency is the Takisung Beach which is located in Takisung District. This tourist attraction is one of the largest contributors to regional revenue in the tourism sector. The development of Takisung tourism also advances the community's economy. Therefore there is a need for a tourism development strategy on Takisung Beach so that the application of city branding by developing the tourism sector. It is considered as the fastest to affect regional economy because it involves the community directly, and tourism has the potential to develop economic opportunities through tourism industry by involving the community. The research method used a qualitative research approach and descriptive type. Researchers conducted structured interviews with informants in Tanah Laut Regency Government (Tourism Office), Takisung Beach UPT (Technical Implementation Unit) and parties from tourism awareness groups called POKDARWIS, using data analysis, namely SWOT analysis. The results showed that Tanah Laut Regency Tourism Office had tried their best in developing the existing potential. The strategy carried out by Tanah Laut Regency Tourism Office includes several steps, namely preservation, coaching and development, which are said already run well. To support its existence, several facilities have been provided by Regional Government and the private sector which are classified into several aspects, namely the aspects of attractions that are differentiated based on the criteria of what can be seen (something to see), what can be done (something to do), and what can be purchased (something to buy); accessibility / transportation aspects; facilitation aspects consisting of hotels and inns, restaurants, souvenir shops / stalls, clean water and sanitation infrastructure, solid waste, electricity networks, telecommunications facilities and infrastructure, gazebos / shelters and other supporting facilities; as well as information and promotion aspects.

Problem: Despite the growing problems of global alcohol abuse, accurate information on the prevalence of alcohol abuse among university students in Kenya is still inadequate. Objective: The study therefore aimed to determine the prevalence and socio demographic determinants of alcohol abuse among university students Design. The study design was a cross-sectional analytical, that utilized quantitative methods. Setting: The study was conducted in Kakamega County, located in Western Kenya. Sample: Stratified random sampling was utilized to select the study group. Analysis: Data was analyzed using SPSS version 25.0. Both descriptive and inferential statistics were used. Data presentation was done using frequency tables, charts and in narratives. The alpha level for all the computations was considered significant at an α <0.05. Main outcome measures: The Alcohol Use Disorders Identification Test questionnaire (AUDIT) was used to assess the prevalence of alcohol abuse Results. The participants included 112 students in year 1, 101 students in year 2, 80 students in year 3 and 162 students in year 4. Prevalence results showed that majority of the respondents (78.9%) claimed to have never taken a drink containing alcohol and most of the respondents (86.5%) were at low risk level of alcohol abuse with scores of between 0-7 in the AUDIT. The study found significant association between the prevalence of alcohol abuse and the year of study, marital status, family's economic status and the living arrangements (with whom). There was no significant association between the prevalence of alcohol abuse and age, course of study undertaken and place of residence. Conclusion: It was concluded that alcohol abuse is generally less prevalent among university students and is associated with year of study, marital status, family economic status and living arrangement. Recommendation: Based on the findings of this study, there is need to detect, strengthen various policies and programs and accordingly make changes to address the factors that contribute to alcohol abuse in the institutions of higher learning in Kenyan.

The sponge Suberites carnosuswas collected during low tides from West Coast of Mumbai. Crude extract was obtained by taking 10 gram of sponge samples in10 ml of methanol. In the present investigation we found the crude protein contents in Suberites carnosus as 0.096 mg/mL. The Neuromodulatory Na (+)-K+ ATPase activity and AChE on Sprague dawley rat brain and chicken brain extract may contribute to the pathogenesis of metabolic complications of the central nervous system, and that the undetectable enzyme activity in chicken brain convulsing chicken brain may result from considerable damage or necrosis of brain tissue during seizures. In A Ch E our study is evident that both the sponge extract showed enzyme inhibitor activity at certain concentrations. In hemolytic activity showed potent toxin which is responsible for hemagglutination. Hemagglutination activity is generated by the presence of protein and the protein found in sponges which usually show hemmaglutination activity that might be because of presence of lectin which showed hemolytic activity. In CAM study showed that methanolic extract has strong antiangiogenic activity. The protein bands showed lectins have variety of effects on cells, such as agglutination, mitogenic stimulation, redistribution of cell surface components, modifying the activity of membrane enzymes, inhibition of bacterial and fungal growth, cell aggregation, toxicity, immunomodulation.

The purpose of the study was to evaluate the physicochemical and sensory properties of non-descriptive deshi and naked neck chicken meat. A total of 40 male and female mature Naked neck chicken (NNC) and non-descriptive deshi chicken (NDDC) were purchased and the chickens were randomly allocated to a 2 (Sex) × 2 (Breed) factorial arrangement in a completely randomized design. The carcass properties of the NNC and NDDC thigh, drumstick were alike (P>0.05) except for breast muscle. Sex affected on all physicochemical properties of carcass. Breed, sex and post slaughter time interactions effects on color attributes of drumstick and thigh meat except for breast meat CIE redness (a*) and CIE yellowness (b*) values. The pH value differed significantly (P<0.05) among the breeds, sex and post slaughter time. The sensory traits evaluations of the chicken breeds were alike (P>0.05). Fatty acid profiles of the chickens were not affected (P>0.05) by sex or breed. The ratios of omega-6 (n-6) and omega-3 (n-3) fatty acids were significantly lower in both breeds which are anticipated in reducing the risk of many heart-related illness. Therefore, the results obtained from this study could be contribute to stimulate the production of naked neck and non-descriptive deshi chickens as well as increases the consumer’s consciousness for healthier meat choices.

A 42 year old lady approached OPD of the Ayurveda hospital, Aniyakanda, Kandana, Sri Lanka and got registered in OPD in February, 2016. She was seeking leach therapy for bluish, dilated and twisted varicose vein at the right poplitial fossa. She reported no history of diabetes mellitus on the past but on advice she did basic laboratory investigations prior to leach therapy i.e FBS, BT and CT. The blood report showed FBS of 220 mg/dl dated on 1st of March 2016. This patient was investigated as recently diagnosed case of diabetes mellitus and laboratory test was repeated 03/03/2016 to confirm diagnosis which revealed FBS of 201 mg/dl and PPBS of 240 mg/dl. Patient was advised not to take any allopathic medicine. Treatment was employed according to ilaj bil dawa (Pharmacotherapy) , half a cup of decoction was prescribed twice a day which consisted 15g of Amla (Phyllanthus embilica),15g of Gilo (Tinospora cordifolia),15g of posth e Neem (Azadirechta indica), and 15g of Darhaldi (Coscinium fenestratum) along with appropriate ilaj bil ghiza (Dietotherapy) prescribed. Patient was assessed every other week with repeated FBS for a period of 3 months. The observed mean FBS during the course of treatment was 136 mg/dl. At the end of this case study the FBS was found to be 108 mg/dl. Efficacy of variety of mufrat advia (single drug) has been already established by some studies. We need to conduct randomized clinical trial in larger sample size in order to establish the effective management for DM.