Vitamins are organic substances that the body need; it obtains and absorbs them from plants and animals. Cobalamin, another name for vitamin B12, is a substance that belongs to the cobalamin family. Deficiency of cobalamin affects the heart uses energy, causing arrhythmia and enlargement of the left ventricle, demyelination, causing neurological symptoms such as numbness, tingling, and difficulty walking Apathy, anorexia, irritability, growth retardation, and developmental regression. Cardiovascular disease (CVD) is the leading cause of mortality in developed countries. It was determined that B12 is an essential micronutrient for a healthy brain in young people and the elderly. Various conditions are responsible for B12 deficiency. If there is a nutritional shortfall, prompt and appropriate supplementation is required. This supplementation can prevent the damage to nervous system. Deficiency may leads to cognitive decline and vascular risk factors in neuropsychiatric disorders, cardiovascular disease, and heart fail. Some cardiovascular or psychological disorders are related to anxiety, dementia and depression, heart attack which can be improved with B12 supplementation.

Talon cusp is an uncommon dental anomaly characterized by the presence of an accessory cusp-like structure projecting from the cingulum area of an anterior teeth. This anomaly generally poses problems for the patient in terms of esthetics, caries control and occlusal accommodation. This cases report with mini-review presents a brief classification of talon cusp, summary of published case report worldwide, and a unique occurrence of maxillary talon cusp in a 23-year female and 9-year male patient. The clinical and radiographic findings, along with the management of this rare dental anomaly are discussed.

Ebi Yeibo’s poem The Forbidden Tongue is a powerful example of how Ijaw proverbs and idioms can be used to explore the cultural and historical experiences of the Ijaw people. The poem makes use of Ijaw proverbs and idioms to convey a strong sense of nostalgia for a lost culture and tradition. By analyzing the parables/ idioms of the poem, we can gain a deeper understanding of the poem’s meaning and significance. The poem also raises important questions about the preservation of the heritage. The title of the work is “The Significance of Ijaw Proverbs and Idioms”. The aim of the work is to explore the cultural and linguistic significance of Ijaw proverbs and idioms. The methodology used is literary analysis of Ijaw poems and texts. The theoretical framework is based on the concept of linguistic relativity, which suggests that language influences thought and culture. The contribution to knowledge is a deeper understanding of the role of proverbs and idioms in Ijaw.

The integration of professional experience, patient preferences, and the best available evidence has become the cornerstone of evidence-based practice (EBP), which has been widely accepted in the field of healthcare. This review looks at the value of EBP, adoption tactics, implementation obstacles, and how it affects patient outcomes in different hospital settings. This review highlights the significance of EBP in enhancing healthcare quality, patient satisfaction, and cost-effectiveness through an examination of recent literature. It also covers the obstacles to implementing EBP and provides advice on how to get beyond them.

In fact customs are the doorkeeper of international trade. All international trade must the processed by the respective national customs and such a processing takes time. In order to facilitate trade, each party shall adopt or maintain simplified customs procedures for the efficient release of goods, instruments sufficient to cover payment of the customs duties, taxes, and fees its customs authority ultimately applies in connection with importation of the good. There is no doubt that trade facilitation activities have a positive impact for international traders when they are implemented effectively. Streamlining customs formalities for imports, exports, and transit of goods has the multiple benefits of increasing trade activity while reducing bureaucratic red tape and expensive delays for traders as well as lessening administrative costs at the border. Primarily, customs authorities facilitate international trade by overseeing the import and export of goods. They are tasked with enforcing trade regulations, assessing and collecting customs duties and taxes, and ensuring the correct classification of goods according to international nomenclature. Moreover, customs play a crucial role in maintaining security by preventing illegal trade. They implement border control measures to halt the smuggling of illicit goods, such as drugs, weapons, and counterfeit products, thereby contributing to national and international security.

World Railways is making significant progress in introducing high-speed trains to fulfil the increasing demands of the traveling public. Massive energy is needed for electric railroads. Many railroads operate their specialized power plants. An energy-storage grid-tied photovoltaic solar plant has been proposed as a strategy to boost the capacity of the rail network grid connection and enable the railway to become self-sufficient. To use the ballast-less rails as energy transporters, The current plan calls for installing solar panels along an HS train network. Ballast-free tracks require very little upkeep, and the space between them provides plenty of surface area for the installation of PV module arrays to harvest solar energy. This generated energy will feed into the main power line by using the concept of an on-grid solar system this energy is not more in numbers to drive the entire traction system, but it helps a lot. From this project we have developed hybrid parallel power sharing for the railway network, under this project the current will be shared in the main power line by matching the grid frequency and voltages. The primary power is solar when it can generate enough electricity. Still, in an abnormal condition, like in the absence of sunlight, the main power continuously feeds electricity without disturbing the traction system.

Odontogenic keratocyst is a common and aggressive cystic lesion derived from tooth remnants in the jaw. It is frequently found in the posterior mandible and less common in the maxilla. This report presents a rare case of an odontogenic keratocyst in maxillary sinus which associated with ectopic third molar. Due to its symptomatic resemblance to other maxillary sinus lesions such as sinusitis or antral polyp, pathologists often face challenges in accurately and promptly diagnosing odontogenic keratocyst.

A plethora of research has implicated hundreds of putative biomarkers for depression but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance diagnosis, treatment, and prognosis. This lack of progress is partially due to the nature and heterogeneity of depression, in conjunction with methodological heterogeneity within the research literature and the large array of biomarkers with potential, the expression of which often varies according to many factors. We review the available literature, which indicates that markers involved in inflammatory, neurotrophic, and metabolic processes, as well as neurotransmitter and neuroendocrine system components, represent highly promising candidates. These may be measured through genetic and epigenetic, transcriptomic and proteomic, metabolomic, and neuroimaging assessments. The use of novel approaches and systematic research programs is now required to determine whether, and which, biomarkers can be used to predict response to treatment, stratify patients to specific treatments, and develop targets for new interventions. We conclude that there is much promise for reducing the burden of depression through further developing and expanding these research avenues.

Language plays a fundamental role in combatting HIV and AIDS. In Kenya, English and Kiswahili are used as the languages of communication in HIV and AIDS related issues. The literacy rate in Kenya stands at 87.4% but research has indicated that only 17% of the population speak and use English effectively while, 65% speak and understand Kiswahili. The use of Kiswahili in health communication cannot be underscored given the fact that majority of the Kenyan population can understand and interpret Kiswahili messages received in a communication string. The fight on HIV and AIDS includes use of songs and poetry. A number of Kenyan artists have invented ways of fighting this scourge in their use of music and this entails use of metaphor in their songs. One such musician is Jackoniah Oyoo who employs metaphor in his song Merimela. Human beings use metaphor to make sense of reality. Metaphor is defined as understanding and experiencing one kind of thing in terms of another. In this scenario, a concrete or clearly organized source domain, being more clearly related to physical and bodily experience, is used to talk about a more abstract and less clearly structured target domain. Metaphorical conceptualization of concepts is so natural and at times unconscious to human beings that they do not even realize that they are using metaphor. This article seeks to examine the metaphorical conceptualization and interpretation of the metaphors used in the song Merimela. The ubiquity nature of metaphors makes it possible for a number of metaphors to be used in the song Merimela. This article reveals how metaphor reflects and structures Kenyans understanding of reality particularly the fight against HIV and AIDS.

Background: Unani system of medicine is based on the theory of Mizaj and Akhlat which is considered as the basics of Unani therapeutics. Mizaj is defined as the admixture of four humours (Akhlat), the quantity and quality of which determines the particular Mizaj of an individual. Every individual has its own unique Mizaj (temperament), hence reacts to various internal and external stimuli viz. Air, water, diet, drug, climate, emotions, body reactions etc. differently according to temperament. Hence, Mizaj plays an important role in diagnosis and treatment of any disease. According to the classical texts of Unani Medicine, it is the concentration, quality and quantity of humours which forms the base and cause of health and disease in an individual. As per Unani doctrine, Mar’d (Disease) is caused either due to Su’ Mizaj (abnormal temperament), Su’tarkib (abnormal composition/structure) or Taffaruk Ittesal (discontinuity). This study was conducted at Majeedia Hospital, Faculty of Medicine, Hamdard University, New Delhi India to evaluate the Mizaj (Temperament) of patients of COPD. Out of 60 patients enrolled for the study, 52 (86.6%) were Balghami, 03 (5%) were Damwi, 05 (8.3%) were Safravi and none was of Sawdawi Mizaj. Thus, it was evident that COPD is more common in Balghami Mizaj patients.

Criminal justice system administers justice and safeguards the lives and properties of individuals in the society. It is regarded as the stage a defendant passes through until the final determination of his case. One of these stages is the criminal trial of the defendant. Criminal trials are often bedeviled with challenges relating to the appropriate procedures to be followed for proper administration of justice in respect of a criminal charge. When the prosecution or the court faults procedures, it affects the constitutional rights of the defendant and often leads to injustice. When a charge is preferred before the court and the plea of the defendant is taken based on the charge before the court, courts in most cases have formed the usual practice of convicting the accused person based on the evidence of the prosecution whose evidence discloses a different offence from the one charged. This practice violates procedural rules and it is a breach of the right to fair hearing of the defendant. This study examined the procedure in criminal trial, the duties of the court in criminal trial and the constitutional provisions on the rights of the defendant. The study adopted doctrinal research methodology with specific reliance on primary and secondary sources such as judicial decisions, statutes, textbooks, articles, online materials among others. The study concluded that the necessary procedural steps should be observed where the evidence of the prosecution discloses a lesser or different offence other than the one charged and pleaded to by the defendant.

This research aims to analyze the weaknesses of the current regulations for examining suspects in Indonesia currently and to find the legal reconstruction for investigating suspects based on Pancasila values of justice. The research method used is sociological legal research or empirical legal research, using the constructivism paradigm. The approach method used in this research is social legal research. This research uses primary data and secondary data. Data collection techniques through literature study, interviews, and questionnaires. The collected data was analyzed qualitatively. The research results show that the weaknesses in the legal substance of the regulations regarding the examination of suspects, namely: the Criminal Procedure Code has not regulated the legal consequences of deviations from suspects' rights to be free to provide information about investigators and the results of investigations, the Criminal Procedure Code has not regulated supervision of investigators' actions, including in examining suspects, and the Criminal Procedure Code has not regulated alleged irregularities in the examination of suspects. as the object of pretrial examination. Weaknesses in the legal structure, namely weak supervision of investigative institutions over the investigation process, limited regional police institutions in providing free legal aid, and the absence of a police budget to provide interpreters and translators for suspects, and weaknesses in legal culture, namely violations of the rights of suspects. suspects' rights, investigative engineering, individual investigators involved in bribery, and investigators who do not understand local culture. Therefore, It is necessary to reconstruct the values of justice and norms in the regulations for examining suspects so that they are based on the Pancasila values of justice. The value of Pancasila justice, especially Principle 2 of Just and Civilized Humanity, must be reflected in the provisions for examining suspects so that suspects are truly made into subjects who have dignity and respect that must be respected by investigators and protected by the state. Meanwhile, the reconstruction of norms in the regulations for examining suspects so that they are based on Pancasila values of justice, namely improvements to Articles 52, 117, 77, 79, and Article 81 of the Criminal Procedure Code.

Therapeutics systems are governed by public health laws of the nations in which these are rolled out & practiced. The current article discusses the therapeutic system of Homoeopathy of AYUSH in India & the public health laws that govern this therapeutic system in India. The next step which the article goes through is the journey of the therapeutic system in the nation which becomes the pivotal for the article. The current article deals with the current situation of the homoeopathic therapeutic system at global followed by the national level. As an intervention strategy to deal with the roll out modalities of homoeopathy, the article discusses the journey of its related public health laws also. Finally, the article discusses the role of homoeopathy of AYUSH ministry of India in the current context & proposes a multi stage involvement based on the successful therapeutics in Homoeopathic Materia Medica. The focus of the article on homoeopathy & its related public health laws is critical as it can cover masses as it is cost effective, therapeutically effective & has no side effects. In order to achieve the roll out of these beneficial properties, the related public health laws need effective implementation.

A seropositive patient who developed a granular cell tumor on the dorsum of the tongue is referred. The lesion was surgically excised. His clinical state is thoroughly studied, along with the histopathological and immunohistochemical examinations findings. Numerous histogenesis theories and the appropriate tumor treatment are mentioned within the article being always in accordance with the relative literature. The case mentioned contributes to the literature by being the first report of a seropositive patient with a tongue granular cell tumor ever noted.

Triumfetta cordifolia is a medicinal plant that has been widely utilized in Africa for its therapeutic properties in treating various ailments. The purpose of this research was to investigate phytochemicals and in vitro antioxidant activity of the leaf extract of T. cordifolia. Standard methods were employed to conduct qualitative phytochemical screening of the plant extract. This study used the DPPH (1, 1diphenyl-2-picryl hydrazyl) radical scavenging and ferric reducing antioxidant power method to assess antioxidant activity. Phytochemical analysis of T. cordifolia leaves indicated the existence of saponins, tannins, terpenoids, cardiac glycosides, alkaloids, flavonoids but no anthraquinones. In the DPPH scavenging test, the IC50 value of the methanolic extract was discovered to be 1.29 µg/mL, and the standard reference value for ascorbic acid was 2.14 µg/mL. The leaf extract of T. cordifolia displayed stronger inhibition of DPPH activity, showing a higher potency than ascorbic acid. The DPPH scavenging activity was also shown to increase with concentration. In FRAP assay, the T. cordifolia leaf extract and the ascorbic acid revealed reducing power of 71.01±0.15 and 548.39±1.62 μM Fe2+ per mg of extract, respectively. The FRAP assay demonstrated that ascorbic acid exhibited greater antioxidant activity than the leaf extract of T. cordifolia. The presence of flavonoids and phenols in T. cordifolia leaves may account for the observed antioxidant activity. In conclusion, the study's findings suggest that that T. cordifolia leaf extract could be a source of lead compounds with promising antioxidant activity.