Introduction: Cranial wounds encephalic penetrating by stab are rare and repesent 0.4% of Head trauma. They are often observed in an attempt at autolysis in mentally ill people, or in physical aggression. We report here a case of an adolescent victim of attack by the penetration of a knife into his brain. Patient and method: This is a patient aged 17 years old, with no known medical history, admitted to the Emergency Reception Department of the Gabriel TOURE University Hospital for open head trauma following a physical attack with the penetration of a knife inside his headrane. The entire blade of the weapon was lodged in his brain parenchyma. The entry point was the right parietal bone. The patient had a Glasgow score of 15/15, with good hemodynamic status. The cranial scanner encephalic which was carried out a few minutes after his admission high lighted the presence of the knife blade at the level of parietal and temporal lobe of her hemisphere right. Result: The patient was operated successfully with extraction of a knife whose blade measured 6 to 7cm. A good postoperative evolution followed. Conscious and without motor deficit, he received a follow-up CT scan on day 7. Then he was released from the hospital with out patient follow-up. Conclusion: Cranial wounds-encephalic by penetration of a bladed weapon are very rare. The CT scan in emergency is the key examination to clarify the location, the number of foreign bodies, as well as brain lesions. They require rapid surgical treatment after CT evaluation. Their prognosis remains reserved regarding the severity of the head trauma, endocranial vascular lesions and infections.

This article examines the potential and limitations of director rotation as a response to the "boardroom bubble" phenomenon in Nigerian companies. Gaining traction as a key corporate governance practice, director rotation seeks to mitigate stagnant decision-making within boards. The research explores how this approach can enhance corporate governance, accountability, and oversight. Our study suggests that while director rotation holds significant promise in reducing board entrenchment and strengthening corporate governance, it is not without drawbacks. These drawbacks include: Lack of independence among directors, reduced knowledge continuity on matters such as ESG (Environmental Social and Governance) factors or long-term strategies, difficulty finding suitable successors who share their predecessors’ characteristics (e.g., gender) as well as turmoil created when introducing inexperienced members onto Boards at times of crisis. Additionally, it does not address other important aspects of board diversity i.e., racial or ethnic background or educational achievements, which remain overlooked through this process alone. While acknowledging the benefits of rotation as a potential remedy for the “boardroom bubble,” this paper advocates for a nuanced approach to board rotation in Nigeria. Our research undertakes a comprehensive examination of Nigeria’s legal and regulatory landscape for implementing rotational boards, employing a rigorous doctrinal approach. The analysis delves into primary sources of data, such as the relevant Acts of the National Assembly and pertinent case law, while the secondary data are mainly books, journals, periodicals and web-based materials. In addition, the work proposes further research to explore specific regulatory frameworks and best practices tailored to the Nigerian context.

Background: Acute diarrhea poses a significant health threat to children globally, often leading to severe morbidity and mortality, particularly in developing countries. Electrolyte imbalances, including hyponatremia and hypokalemia, are common complications associated with acute diarrhea, further exacerbating the risk of adverse outcomes. Objective: This study aimed to evaluate the frequency of sodium and potassium abnormalities, specifically hyponatremia and hypokalemia, in children presenting with acute diarrhea. Methodology: A prospective cohort study was conducted at the Pediatric department of a tertiary hospital from July 2022 to June 2023. A total of 130 pediatric patients aged up to 5 years, presenting with acute diarrhea, were included in the study. Clinical examinations were conducted, and demographic data, including age, gender, residence, and socioeconomic status, were recorded. Serum sodium and potassium levels were determined from venous blood samples, and hyponatremia and hypokalemia were defined as sodium levels <130 mmol/l and potassium levels <3.5 mmol/l, respectively. Statistical analysis was performed using SPSS 24.0. Results: The mean age of the patients was 2.38 years, with a disease duration of 3.54 days. Male patients accounted for 60% of the cohort, and urban residency was predominant (55%). Clinical symptoms included loose motion (100%), abdominal pain (70%), fever (35%), vomiting (31%), and lethargy (27%). Hyponatremia was observed in 30% of patients, while hypokalemia was present in 40% of cases. Conclusion: Sodium and potassium imbalances are prevalent among children with acute diarrhea, highlighting the need for vigilant monitoring and appropriate management strategies to prevent adverse outcomes. The high incidence of hyponatremia and hypokalemia underscores the importance of early recognition and intervention in pediatric patients presenting with acute diarrhea.

Government is aiming to establish India as global manufacturing hub through various policy measures and incentives to specific manufacturing sectors. Launched in 2014, the Make in India initiative aims to transform India into a manufacturing, design, and innovation hub. The initiative spans 27 sectors, supported by policies like PLI schemes, GST, corporate tax reduction, and ease of doing business reforms. The One District One Product (ODOP) initiative promotes regional development by highlighting unique products from each district, fostering socio-economic growth. In this paper we have taken quarterly and yearly data of Manufacturing Sector 2012-13 to 2023-24 from Ministry of Statistics and Programme Implementation. In this paper we have seen the growth rate on yearly basis, CAGR, trend analysis and performance of Manufacturing Sector in pre and post-pandemic period. Is there any fluctuations in the growth rate of this sector during pre and post pandemic or any type of pattern?

Background: Long COVID, or post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms that last weeks to months following the acute phase of COVID-19. This condition affects a substantial number of COVID-19 survivors, impacting multiple organ systems and significantly reducing quality of life. Method: This literature review synthesized research on the delayed and long-term physical side effects of COVID-19. A comprehensive search was conducted using Google Scholar and PubMed to identify open-access, English-language studies. Keywords included "COVID-19 side effects," "long COVID," and "post-acute sequelae of COVID-19." Relevant studies were screened and analyzed for key findings and limitations. Findings: The review identified significant long-term symptoms affecting COVID-19 survivors, including fatigue, dyspnea, chest pain, cognitive impairments, and musculoskeletal pain. These symptoms persist across diverse populations, regardless of the severity of the initial infection. Key limitations in existing studies include small sample sizes, single-center designs, and potential biases in self-reported data. Conclusion: Long COVID presents a major public health challenge, necessitating a multidisciplinary approach to manage its extensive and multifaceted impacts. Continued research, standardized diagnostic criteria, and comprehensive care models are essential to address the long-term needs of COVID-19 survivors and mitigate the broader economic and social burdens.

In recent years, biogenic approaches to crafting silver nanocomposites have garnered considerable attention outstanding to their potential in developing semi-healthcare and para-pharmaceutical consumer products. This study presents a novel, environmentally benign method for synthesizing silver nanoparticles operating the previously unexplored mucus derived from the Common carp (Cyprinus carpio). Thorough characterization of the resultant materials using UV–Visible Spectroscopy and FTIR Spectroscopy techniques confirms the successful formation of silver nanoparticles within the common carp mucus matrix. Subsequent testing against a diverse selection of bacterial strains, including Gram-positive (Escherichia coli) and Gram-negative (Bacillus subtilis), as well as a fungal strain (Terbinafine), using the well diffusion method, reveals potent antibacterial and antifungal properties exhibited by the silver nanoparticles embedded in the mucus matrix. Further experiments were conducted to ascertain the inhibitory concentration against both bacterial strains. Cytotoxicity assessments conducted via in vitro analysis using blood intriguingly heightened cytotoxic activity of the biogenically synthesized silver nanoparticles within the biocompatible mucus, suggesting potential applications in anticancer therapies. Moreover, evaluation of antioxidant properties (DPPH, TPC, TFC) and enzymatic activities (SOD, POD, CAT, TSP) of the mucus-based nanoparticles demonstrates promising outcomes, indicative of their potential utility in formulating antimicrobial.

The aim of this research is to analyze the influence of motivation and self-confidence of swimming athletes on the results of the 50 meter freestyle. This research is descriptive quantitative with a correlational approach. The sample for this research was selected through purposive sampling, so that the athletes involved were athletes who had won at the provincial level. A total of 32 athletes aged 13 – 17 years, athlete characteristics (mean ± SD), age 16.03±3.6 years, training experience 6.8±7.8 years, competition involvement in 1 year is 2 - 4 times. The instrument uses a questionnaire and a 50 meter swimming test which is then recorded based on the best time. The data shows a normal distribution and the linearity test is carried out through the F test (p-value > 0.05) which explains the influence between motivation and self-confidence and the results of the 50 meter freestyle swimming which are declared linear. Correlation results show that there is a positive and significant relationship between motivation and self-confidence on the results of the 50 meter freestyle swimming 0.000 < 0.05. The coefficient of determination shows that the influence of motivation and self-confidence on freestyle swimming results is (R2 = 0.877) or 87.7%. The conclusion is the importance of psychological factors such as motivation and self-confidence in achieving good results in swimming. These results can serve as a guide for coaches and athletes to strengthen motivation and build self-confidence which in turn can improve performance and achieve better results in swimming competitions.

Background- Blood pressure (BP) ≥140/90 mmHg, taken after a period of rest, on two occasions or ≥160/110 mmHg on one occasion in a previously normotensive woman is labeled as pregnancy-induced hypertension. [1,2] Pregnancy-induced hypertension (PIH) is a pregnancy-specific condition that includes gestational hypertension, pre-eclampsia (PE), and eclampsia (E). It is linked to intrauterine death, abruptio placentae, maternal mortality, and intrauterine growth retardation (IUGR) [3, 4]. Aim - to find the prevalence of pregnancy induced hypertension in women attending antenatal clinic in a tertiary care hospital. Materials and methods- Total 200 pregnant women with a gestational age of 20 weeks or greater visiting ANC clinic were included in the study during the period of 5 months (December 2023 to April 2024) at VVP rural hospital, Loni. Demographic details and blood pressure were collected. Data collected was analyzed using Microsoft Excel 2013 and pspp version 1.0.1. Results- Mean age of participant mothers was 23.2 years. Out of total 200 participants, 15 (7.5%) women presented with PIH (8, gestational hypertension and 5, pre-eclampsia and 2, eclampsia). Mean age of pregnant women presenting with PIH was 29 years as compared to the mean age of pregnant women without PIH which was 22 years. Out of 15 participants with PIH, 10 were primigravida, 8 and 3 were from lower and lower middle class respectively. Conclusion- PIH is still important problem and health education and awareness is still needed especially in rural communities.

Background- Anaemia is one of the common health issues that pregnant women and children in developing countries face. Anaemia in pregnancy is related to poor fetal and maternal outcomes contributing to significant morbidity and mortality. Anaemia is a treatable and preventable condition. Aim - to determine the prevalence of anaemia among pregnant women visiting the ANC clinic in a tertiary care centre. Materials and methods- Total 100 pregnant women visiting the ANC clinic in a tertiary care centre were included in the study during the period of 5 months (December 2023 to April 2024) at VVP rural hospital, Loni. The World Health Organization's diagnostic criteria for anaemia was applied for determining hemoglobin levels. Demographic details and hemoglobin levels were collected. Data collected was analyzed using Microsoft Excel 2013 and pspp version 1.0.1. Results- Out of total 100 participants, 51 were anaemic. Out of them, 30 (58.8%) women had mild anaemia, 19 (37.3%) women had moderate anaemia and 2 (3.9%) women had severe anaemia. Mean age of women with Anaemia was 23.3 years as opposed to mean age of women without anaemia which was 26.7 years. Out of 51 cases, 10 (19.6%) women were primigravida, 32 (62.7%) women had birth spacing of less than 2 years, 9 (17.7%) women had birth spacing of 2 years or more. Conclusion- Prevalence of anaemia in our study was comparable to NFHS-5 data. There is need of antenatal and pre-conceptional health awareness about implications of anaemia, preventive measures and spacing between births which will reduce prevalence of anaemia, thus maternal and fetal morbidity and mortality.

Introduction: The presence of distant metastases is one of the important predictive factors of poor outcomes in patients with thyroid carcinoma. It is rarely observed at early presentation of differentiated thyroid carcinoma (DTC). This study aimed to analyze the frequency of distant metastasis in differentiated carcinoma of the thyroid. Methods: This cross-sectional observational study was conducted at the Department of Otolaryngology, Rajshahi Medical College Hospital, Rajshahi, and Department of Otolaryngology Bangabandhu Sheikh Mujib Medical University (BSMMU), from July 2011 to Jun 2012. A total of 40 patients were selected as study subjects by simple random sampling technique. A descriptive analysis of data was carried out by using a statistical package for social science (SPSS) 22.0 for Windows. Result: In this study, a majority (35, 87.5%) of the patients suffered from papillary carcinoma, followed by (5,12.5%) follicular carcinoma. Considering the distant metastasis, 2 (5.71%) patients had metastasis to the lung among the patients with papillary carcinoma (n=35). 1 patient had lung metastasis and another 1 patient had bony metastasis among the follicular carcinoma patients. In terms of distant metastasis, 50% of the patients had distant metastasis from each papillary and follicular carcinoma. Conclusion: This study concludes that metastasis in differentiated thyroid carcinoma is not uncommon. Distant metastasis is more common in follicular thyroid carcinoma than papillary carcinoma. Lung and bone metastasis are common regarding the site of metastasis.

Background- Contraceptive methods are preventive methods to help women avoid unwanted pregnancies. They include temporary and permanent measures to prevent pregnancy resulting from coitus. Indian women prefer to avoid unwanted pregnancy, but appropriate information which affects the decision of contraception is not accessible to everyone. Preference of contraceptive method/s depends on multiple factors. Aim- to study the preferred method of contraception among women of age 18 to 30 years attending a tertiary care centre. Materials and Methods- The cross-sectional study was conducted on 200 married women of age 18 to 30 years attending BVP RMC Loni, Maharashtra. The study duration was of 5 months (December 2023 to April 2024). Pregnant, lactating women were excluded. After taking written informed consent, sociodemographic details and contraception details were recorded. Microsoft Excel 2013 and pspp version 1.0.1 were used for the analysis of the gathered data. Results- Out of 200 participants, only 83 participants were using contraception. Thus prevalence of participants using contraception was 41.5%. Out of those 83 participants who were using contraception, majority i.e 35% participants used traditional method like withdrawal and/or rhythm method, 25% used IUD, 16 % participants preferred OC pills or emergency pills, 8% used combination of any two or more methods, 6% used male condoms, 6% were sterilised, 4% used injectable contraceptive. No participant’s husband had undergone vasectomy. Conclusion - Health education about contraceptive methods is needed. Health and social awareness is needed in men about sharing the burden of contraception.

Fruit and vegetables provide nutrition and food security, income-generating opportunities, ecosystem services, and contribute to cultural identities. Protecting these species, and by extension, demands urgent action. The present study is to understand the diversity of vegetables sold in the markets of Tirunelveli District Tamil Nadu. Field visits were made to the local markets in and around Tirunelveli covering nearly 30 km2. A major survey was done at Tirunelveli Town Wholesale Market Complex, Palayamkottai Market complex, and various farmer markets (Ulaver Santhai). A total of 62 species belonging to 41 genera and 19 families were identified in the study. Out of 62 species, 61 belong to angiosperms and 01 to fungi. Cucurbitaceae is the dominant family with 11 species. Brassica largest genera share 10 species. Totally 20 species of geophytic vegetables were recorded in the study area. Out of them majority (45% of the species) were monocots, and family Brassicaceae, is dominant with 5 species. The present study concluded with an appeal for sufficient, sustained funding to ensure a global rescue plan for vegetable diversity can shift the research and development agenda to focus on nutrition and well-being.

Background: Labor pain is intensely severe, often leading to hyperventilation and hormonal releases that can harm the fetus by reducing oxygen supply and causing metabolic acidosis. Effective pain management during childbirth is crucial for both physical and mental health. Various pharmacologic and non-pharmacologic methods are available, with epidural analgesia being a prominent choice. It is widely used in high-income countries, provides substantial pain relief, and benefits uterine contractions and placental perfusion. Epidural analgesia has potential side effects and controversies, such as delayed labor and higher intervention rates. Aim of the Study: The study aimed to examine the impact of epidural analgesia on the mode of delivery. Methods: This observational study, conducted from July 2021 to June 2022 at the Department of Gynecology and Obstetrics in a 250-bed District Hospital in Bagerhat, Bangladesh, included 50 participants divided into two groups of 25 each: Group A (with epidural analgesia) and Group B (without epidural analgesia). Approved by the Ethical Committee, the study included women aged 18-35 years, 37-41 weeks gestation, in labor with regular contractions, at least 4 cm cervical dilatation, and a regular fetal heart rate pattern. Excluded were women with medical or obstetrical complications, uterine scars, or spinal deformities. Data were collected via interviews, observations, and clinical examinations. Result: In this study of 50 participants (25 per group), most women were under 30 years old, with mean ages of 22.4±4.5 and 22.9±5.2 years in groups A and B, respectively. Gestational ages ranged from 37 to 40 weeks, and BMIs were 18.5-24.9 kg/m². Both groups had similar parity distributions. Normal vaginal births occurred in 84% (Group A) and 88% (Group B), with LSCS rates at 4%. Group A had 60% male neonates with average birth weights of 2.86±0.27 kg, and Group B had 56% males with weights of 2.88±0.26 kg. APGAR scores were high in both groups. Conclusion: Epidural labor analgesia is safe and does not increase instrumental deliveries or affect neonatal outcomes, making it a viable pain management option. Obstetric care providers can use this information to counsel women.

This research paper evaluates the effectiveness of working individually versus in cooperative groups in a classroom setting of undergraduate students. It also investigates how these two tactics enhance learning outcomes and considers their advantages and disadvantages. The literature review places a strong emphasis on the importance of students’ involvement in the learning process and the need for effective teaching strategies that can aid in students’ different styles of learning. The research involves a sample of undergraduate students who are randomly assigned to complete tasks designed to test their capacity for knowledge acquisition, critical thought, problem solving, and communication. The results of the study are analyzed using statistical methods to determine the effectiveness of each approach in enhancing the learning outcomes of the students. The findings of the study contribute to the existing literature on this topic and provide practical recommendations for educators on the most effective ways to structure learning activities in the classroom.

Background: Rabies is a cosmopolitan anthropozoonosis for which humans are accidental victims. In Morocco, rabies is an endemic disease, with new cases of human rabies reported every year. The aim of our study is to analyze the epidemiological aspects of rabies in the province of Ouarzazate. Materials and Methods: This is a retrospective study using records available at the Ouarzazate Municipal Hygiene Office. It includes 1,759 cases of exposure to animal bites between 2016 and 2019. Results: We identified 1,759 cases of animal bites during the period of 4 years of study, representing an average annual exposure rate of 190/100,000 inhabitants. Most cases were rural (65%). The median age of bitten cases was 28 years, with people under 15 years of age exposed in 32% of cases. Males predominate, with 61.3% of cases. Dogs are the main animal aggressors at 47.8%, followed by cats at 33%. The upper limbs are the preferred sites of aggression (89.2%). Exposure was grade III in 76.8% of cases. Lesions were multiple in 52.1% and superficial in 62.6%. No cases of human rabies have been recorded since 2001, despite 20 cases being exposed to a biologically confirmed rabid animal during our study. Conclusion: Rabies remains a public health concern in the province of Ouarzazate, despite the presence of a national rabies control program. Effective control of this zoonosis requires strengthening education and community engagement, as well as close collaboration between animal health and human health sectors for integrated management of bite cases.