For their protection during the very adverse conditions produce different types of primary and the secondary metabolic compounds. As these stresses progressed in plants, a multi - gene response is triggered which caused changes in many of the proteins, signaling molecules, primary and secondary metabolites, amino acids and so on. The metabolism in plants is disrupted which leads to metabolic enzymes inhibition, substrates shortage, an increased demand of some particular compounds or all these factors combination. In this review, we showcase various kind of abiotic stresses which harms the plant. We also describe how the time scale variable stresses impact profile of secondary metabolites which could be used to identify different stresses. This paper has ability to attract researchers’ attention operating on the quantitative trait locus mapping with metabolites and also metabolomics genome wide linkage.