Appendiceal mucocele is a rare pathology, which poses a double problem by its potential malignancy and the risk of peritoneal pseudomyxoma in case of perforation. We report here the case of a 57 year old patient operated for anal fistula in whom the clinical examination revealed a mass of the right iliac fossa. Ultrasound showed a cystic pericaecal mass. The patient underwent a laparoscopic appendectomy removing the caecal base and the appendicular operative specimen measured 130 mm in length and 64 mm in diameter. Pathological analysis of the specimen confirmed the diagnosis of appendiceal mucocele without malignant cells. The postoperative course was simple and the patient was discharged on the sixth postoperative day. The aim of this study was to show the diagnostic and therapeutic features of this condition in our context.