Background: General anesthesia is very common anesthetic procedure which is used in several surgical approaches. Without general anesthesia many of these surgeries are lifesaving or life-changing and would not be possible. But all medical procedures are associated with some complications, even when they are performed by experts. The severity and rate of these complications depend on patient’s state of health, age or general lifestyle. Though the general anesthesia using is considered safe, but it comes with certain complications. Aim of the Study: The aim of this study was to assess the complications of general anesthesia in different surgeries. Methods: This was a prospective observational study. The study was conducted in the Department of Aneaesthesia, ICU & Pain Medicine, Shaheed Suharawardy Medical College and Hospital, Dhaka, Bangladesh during the period from January 2019 to December 2019. In total 57 participants in treatment under various department of the mentioned hospital and was prepared for surgery were included as the study subjects. All the demographic as well as clinical data were recorded. As per necessity all data were processed, analyzed and disseminated by using MS Excel and SPSS version 23.0 program. Results: As the complications of general anesthesia among our participants, we found somnolence, ‘dry mouth/increased thirst’ and pain in operated place were found in more than 50% cases separately which were found in 67%, 79% and 82% cases respectively. On the other hand, in 25>50% cases disorder of consciousness (25%), ‘weakness and pain of muscles (28%)’, ‘nausea and vomiting (30%)’, headache (33%) and ‘sore throat/hoarseness (37%)’ were found separately which was noticeable. Besides these, breathing problems, urination problems and feeling cold/chills were observed in some cases. Conclusion: Usually, general anesthesia is a safe way for ensuring patient’s safety and comfort during surgery, but till now it is associated with some complications which have to be recognized and deal with. Contentious development in the procedure of using general anesthesia is necessary to reduce unwanted complication.