There is growing trend of psychiatric morbidity among children and adolescents all over the world. Medications are prescribed to this age group mainly depending on data obtained from adult population. Proper study to find out exact burden of the problem and the effects of these drugs to young population has not been done in our part of the world. The study was done to identify the incidence of different psychiatric problems with the most common pharmacotherapy given in children and adolescents. It is a cross sectional observational study conducted in the Psychiatry OPD of Medical College Kolkata by the department of Pharmacology from May 2014 to October 2014. After institutional ethics committee approval and consent from guardians, 86 patients of either sex were included in the study. Patient demographics (gender distribution, age of the patients, diagnosis) and drug-related information (antipsychotic drugs, route of administration) was recorded on a customized data collection sheet. Data was analysed using descriptive statistics. 61.9% in children and 67.69% in adolescent age group were boys. Mood disorder, mental retardation and epilepsy are 3 major diagnosis encountered. Average number of psychotropic drug per prescription was 1.41±0.8. 91.73% drugs were prescribed by generic name. 80.16% of the drugs supplied from hospital pharmacy. Antidepressants (29.75%) most commonly prescribed followed by Antipsychotics (26.44%). 30% patients were receiving polytherapy. We found 1-18 year age group was common in psychiatry OPD. Most common diagnosis was behavioural and neurotic disorders, while the most commonly prescribed drugs were antidepressants and antipsychotics.