Implementation of totally implantable venous access devices (TIVADs) is associated with several complications that can be divided into early complications and late complications. The purpose of the present study was to evaluate the different complications related to TIVADs in a single center in Morocco. Our study is based on a prospective analysis, which took place over a period between September 2015 and March 2016 in oncology department of the Avicenne military hospital in Marrakech, in collaboration with thoracic surgery department and vascular surgery department. 36 patients benefited from the placement of TIVADs, with 18 men and 18 women, with a mean age of 55.5 years (from 22 to 71 years). The type of anesthesia was local anesthesia (LA) in 97% of cases with 3% of cases requiring a slight associated sedation. The preferred route was a percutaneous approach. The surgical approach by surgical dissection of the cephalic vein was used only in 2 patients, in 6% of cases after failure of the percutaneous route. The most used vein in our series was the right subclavian vein (RSCV) in 69% of cases, followed by the left internal jugular vein (LIJV) which presents 14% of patients. All patients received a control x-ray after procedure. 50% of the indications were for breast cancers and digestive cancers. Intervention was difficult in 11% of cases. In our series 3 patients who presented complications: 1 case of pneumothorax (3%), 1 case of thrombophlebitis (3%) and 1 case of costo-clavicular clamp syndrome (3%). Elimination of risk factors such as the choice of a technique, the handling of CCI, the use of echo-guidance, aseptic measures can reduce certain complications and their early and adequate management.