Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS)
Volume-4 | Issue-08 | 981-992
Original Research Article
Antioxidant and Anti-Inflammatory Activity of Arthrospira platensis Var. Lake Chad
Etame Loe Gisèle , Dibong Siegfried Didier, Boudjeka Nguemkam Vanessa, Ngoule Charles Christian, Ngene Jean-Pierre, Kidik Pouka Catherine, Dedande Mbaioundakom
Published : Aug. 30, 2018
Abstract
The objective of this study is to evaluate the antioxidant and anti-inflammatory activity of the aqueous extract of Arthrospira platensis var. Lake Chad, also call spirulina. A phytochemical screening of the aqueous extract was done for the characterization of the secondary metabolites. The microbiological quality was estimated and essays of acute toxicity were made. The anti-inflammatory activity was determined by the method of the oedema led by carrageenan; total phenols were determined and the antioxidizing activity was estimated by the method of trapping of the radicals free of the DPPH. The phytochemical test showed the presence of tannins, flavonoids, sterols, saponosides and alkaloids. Subsequently, during the microbiological quality control, no presence of total coliforms, fecal coliforms, molds and salmonella was observed.