Introduction: The lipid profile of a Bangladesh population, which has a lower prevalence of coronary heart disease, compared with others nations, is studied to determine whether lipid-modifying disease prevention programs are necessary. Aim of the Study: The aim of the study was find out the Lipid Profile and Its Association with Risk Factors for Coronary Heart Disease. Methods: This is a cross-sectional study; a total of 172 patients were enrolled and analyzed. The study conducted during January 2020 to December 2020 at the Department of Cardiology in Department of Cardiology, Shaheed M. Monsur Ali Medical College, Sirajganj, Bangladesh. Result: The study population is shown in more than 30% of patients had hypercholesterolemia, 41(23.84%) patients were at the high borderline (5.17-6.19), and 38(22.09%) patients had high-density lipoprotein. Under low-density lipoprotein, 7(4.07%) patients had high LDL-C, and only 2(1.16%) patients had very high LDL-C. The age distribution of the study; 33.72% of patients were from the age group 40-49 years, and 17.44% of patients were aged more than sixty years. Conclusion: WHR is associated with an increase in TG, TC, and LDL-C and supports the view that abdominal obesity may be an important cardiovascular risk factor. This study emphasizes the role of HDL-C, which may avert the CHD risk in females. Further studies with longitudinal data are needed to assess the risk factors for CHD in high-altitude populations.