Steroid drugs for external use can relieve inflammation but cannot kill bacteria. Topical steroids have been used for about 50 years and their introduction was a milestone in dermatology. Steroids led to the adverse reaction such as skin irritation, blackness, pimples, redness, skin eruption etc. According to the constituents of marketed cream which are mentioned on the label there is no any information about steroidal constituents in preparation. In present investigation, by applying chemical test in marketed preparation and in pure steroidal preparation, an attempt was made to evaluate the presence of steroid in various marketed topical preparation. Adverse reaction produced by the marketed topical preparation led to the starting of this research work and evaluated different marketed preparation for the presence of steroid. Salkowaski reaction, Liberman Bruched reaction, Liberman reaction had been applied to test the presence of steroid. From this research it can concluded that many marketed preparation which promises instant fairness, glowing, brighten skin have a dreadfully negative side and show serious side effect on the skin due to presence of steroid