With the growing population of cancer survivors, the concept of quality of life (QOL) has become important. Chemotherapy-induced peripheral neuropathy (CIPN) is one such common, ailing chronic condition characterized by tingling senstaion, pain and sometimes decreased function of hands and foot, which hampers the QOL of patients post chemotherapy treatment. A PubMed search for ‘chemotherapy-induced peripheral neuropathy’ was done. Despite the volume of recent publications, there are limited preventive or therapeutic strategies for CIPN supported by high-level evidence. Recently the effect of alternative non-pharmacological therapeutic approaches and predictive biomarkers have been explored.As CIPN still affects a mojrity of patients’, there is a need for critical analysis of the literature. The present study aimed to review the literature on chemotherapy-induced peripheral neuropathy and its treatment or other possible interventions.