Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS)
Volume-4 | Issue-05 | 579-586
Original Research Article
A Retrospective Study of Recurrent Respiratory Papillomatosis in West Bengal, India
Saileswar Goswami, Shivaam Kesarwaani, Dipankar Kumar Basumata, Subrata Kumar Das, Anton Dev. X, Maragatham Kubendiran Nandhini
Published : May 30, 2018
Abstract
Recurrent respiratory papillomatosis is a rare benign disease of the upper airway caused by HPV, primarily affecting the paediatric age group. A retrospective analysis of 11 cases of recurrent respiratory papillomatosis was done in the present study extending for 30 years in three Medical Colleges of India. The presenting age of the patients was 2 to 7 years. Around 73% of recurrent respiratory papillomatosis cases had been diagnosed within 5 years of age. In our study, we did not find any case of adult onset recurrent respiratory papillomatosis and all the cases were of juvenile onset. Both males and females were affected equally with a male to female ratio of 1.2: 1. The incidence was more in the population with lower socio-economic conditions. Out of the total 11 cases, 6 patients required emergency tracheostomy for obstruction of the airway due to extensive involvement of the larynx. Microlaryngoscopic removal of the lesions with microdebrider was the primary treatment combined with adjuvant nonsurgical/medical treatments to contain the virus and growth of the tumours. In the case of the 5 (45%) patients presenting with hoarseness of voice without respiratory distress, complete microlaryngoscopic excision of the lesions were possible. However there were recurrences in 3 of these 5 cases, requiring further surgeries. In the case of the 6 (55%) patients, who required emergency tracheostomy for acute respiratory distress, complete microlaryngoscopic excision of the lesions were not possible in the first surgery, due to extensive pathology and there were recurrences in all these cases. Collectively, there were recurrences in 9 cases out of the total 11 cases.