HIV/AIDS is a serious challenge for the developing as well as the developed world. Globally, 35.0 million (33.2–37.2 million) people were living with HIV at the end of 2013. [1] Although many HIV‑infected individuals avoid risky behaviours, still substantial numbers of HIV‑infected persons, continue to engage in HIV transmission risk behaviours. To find out the Socio-Demographic, Behavioural characteristics and Clinical profile of People (Males more than 15 years) Living with HIV/AIDS (PLHA). An institutional based cross sectional study was carried out among People (male >15 years) living with HIV /AIDS (PLHA) attending Anti Retro Viral Therapy (ART) Centre of Calcutta School of Tropical Medicine (CSTM) for 12 months from May 2012 to April 2013. A predesigned and pretested schedule was used as study tool to collect required information. Maximum population (40.5%) belong to the age group 31-40 years followed by 24.1% in 41-50 years. Majority had coital debut at the age of 26-30 years (35.9%). First sexual partner among 41.7% was female commercial sex worker; 74.4% participants were not into monogamous relationship. More than half of study population (51.1%) were currently sexually active and 55.36 % of currently sexually active participant consistently used condom. Majority of the study population suffered from tuberculosis (28.2%) followed by candidiasis (24.5%). PLHA should be trained on safe sex strategy, correct and consistent use of condom among themselves & their partner as well as maintaining monogamous relationship. More involvement of Community Care centre to reinforce, care and counselling, support of PLHA against Opportunistic infection will reduce their poor health burden. IEC activities to promote value based lifestyle with reducing vulnerabilities among PLHA and creating a strong network among PLHA will prevent such harmful behaviour