Cutaneous mesenchymal tumors dermal and/or hypodermic are relatively frequent. They are characterised by extreme clinicopathological heterogeneity and dominated by benign tumors. About a series of 126 cases, we have studied the epidemiological, pathological and evolutive profile of these tumors. This is a retrospective study executed at the department of pathology of Moulay Ismail Military Hospital in Meknes-Morocco, between 2014 and 2016. Results: The average age was 41 years-old (15-84 years old). The sex ratio H/F was 1.2. The lower limb was the most frequent location (35%). The surgical pathologic study focused on biopsy material in 100% of cases. 92% of these tumors were benign. They were mainly represented by lipomatous tumors, followed by fibrous and fibro-histiocytic tumors and vascular tumors. 8 % of the tumors were malignant. These were mainly fibrous tumors, followed by vascular tumors. The immunohistochemical study was performed in 11 cases. Surgical treatment was executed in 65% of cases. The evolution was favorable for benign and majority of malignant tumors after a large surgical treatment. One case of death and one case of recidivism were noted. Benign cutaneous mesenchymal tumors have a good prognosis. However, the diagnostic and therapeutic management and the prognostic evaluation of cutaneous sarcomas remain difficult