Literature has confirmed the bitter melon is useful to reduce the levels of blood glucose. A functional food was developed by extracting critical ingredients from bitter melon with advanced techniques. The new ingredient was generally termed as bitter melon peptide, of which had been used as major component of the product in this research. Purpose of this research is testing the effectiveness of this new product in controlling the blood glucose levels of the diabetes mellitus (DM) patients. As a preliminary study, 25 samples were recruited on the basis of volunteer through the participated pharmacies, 52% are female and 80% are aged 45 and above. After a three months period of experiment, the data indicated significant differences in the values of HbA1c and FG between starting (T0) and second month (T2), and T0, and the third moth (T3). The test concluded that the product was effective in reducing blood glucose.