Atherogenic cardiovascular risk assessment is important in the management of dyslipidaemia associated with antiretroviral therapy (ART). Generally, Castelli’s Risk Index (CRI), Atherogenic Index of Plasma (AIP) and Atherogenic coefficient (AC) are becoming useful indices as risk predictors for cardiovascular disease (CVD). We studied the importance of these indices in identifying at-risk HIV individuals receiving treatment. Eighty (80) HIV-patients comprising treatment (n=40) and treatment-naïve (n=40) groups with age- and sex-matched were enrolled. Traditional lipid parameters {Total cholesterol (TC), Triglycerol (TG), and HDLc} were analyzed using spectrophotometry. The LDLc was calculated using Friedewald equation. Non-HDLc, CRI-I (TC/HDLc ratio) and CRI-II (LDLc/HDLc ratio), AIP {Log10 (TG/HDL-c)} and AC {(Non-HDLc)/HDLc} were also calculated. The CD4+ cell count was determined using flow cytometry. The correlations between atherogenic indices and lipid profile were determined using Pearson’s correlation.