Nurses are facing practice problems that causes disturbing and stressful situation. The most common and prevalent issue is moral distress. Moral distress is affecting performance of professional nurses at health care setting. Cross-sectional study design was used. Questionnaire consisted on 5 point Likert scale adopted was used to know the impact of moral distress on nurse’s performance with sample size 187 Nurses from Public Hospital Lahore. Finding of the study shows that there is a significant negative (reciprocal) impact of moral distress on performance of nurses The current study concludes that moral distress decrease the job performance of the nurser’s at hospital settng. This study revealed the negative relationship between moral distress and nurses’ performance. The study findings will enable the health care organizations to enhance the performance of staff nurses by minimizing the factors that are causing moral distress among nurses. Hospital can arrange workshops and education sessions to give awareness to deal moral distress situations