The objective is to explore the effects of law and code-oriented and caring-oriented organizational ethical climates on physician–patient trust and interactions. A questionnaire survey was adopted and physicians of a case hospital were selected as the survey participants. A total of 116 valid questionnaires were collected, which were then analyzed through multiple regression analysis. The law and code-oriented organizational ethical climate had a significant and positive effect on physician–patient trust and interactions. In an increasingly complex medical environment, physicians must be aware of their hospitals’ organizational ethical climate and understand their roles and tasks pursuant to the hospitals’ missions, visions, and values. Such awareness and understanding will strengthen physician–patient relationships and enhance medical service quality