This research was done to formulate an optimized Chronotherapeutic Timed Release Tablets (ChrTRTs) containing theophylline, a potent bronchodilator used in the management of asthma in the inner core as a Chronotherapeutic drug delivery system. Theophylline core tablets (TCT) containing Irvingia gabonesis gum (2.5 %w/w) as binder and maize starch (15%w/w) as disintegrant were prepared at a compression pressure of 30 units on the arbitrary load scale. ChrTRTs containing the inner core tablet with Anarcadium occidentale gum, Irvingia gabonesis gum, and Sodium Starch glycolate at varying concentrations (0, 0.5, 1 and 2 % w/w) to achieve a predetermined lag time for chronotherapy were prepared at a compression pressure of 35 units on the arbitrary load scale. The parameters determined were tablet hardness, friability, drug content, disintegration test and in-vitro dissolution studies. The release profile showed that all the ChrTRTs tablets exhibited a distinct lag time before burst release of the theophylline. Lag time was dependent on the amount of starch glycolate in the outer shell. The lag time of all formulations was between 0 to 6 h and it decreased with an increase in the amount of starch glycolate in the outer layer. Formulation ChrTRT2 was considered as the optimized formulation since it yielded a predetermined lag time of 4 h before burst release of theophylline from the ChrTRTs. The indication is that this design can be exploited and utilized to achieve chronotherapeutic drug delivery systems of theophylline for the management of chronic illnesses such as asthma