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Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS)
Volume-3 | Issue-07 | 752-755
Original Research Article
Assessment of Colocasia esculenta Mucilage as Suspending Agent in Paracetamol Suspension
Alalor CA, Augustine K
Published : July 25, 2017
DOI : 10.36348/sjmps.2017.v03i07.013
Abstract
The purpose of this study is to search for more affordable as well as effective natural excipients that can be used as viable alternative for the formulation of pharmaceutical suspension. The suspending properties of mucilage of Colocasia esculenta were evaluated comparatively with those of compound tragacanth and acacia in Paracetamol suspension. Characterization tests were carried out on Colocasia esculenta mucilage. Sedimentation volume, rheology, pH, degree of flocculation and redispersibility were the evaluation parameters. The values obtained were used as basis for comparison of the suspending agents studied. Colocasia esculenta mucilage showed comparable suspending ability as acacia and compound tragacanth although Colocasia esculenta mucilage was found to be less viscous than acacia and compound tragacanth. Also, the redispersibility of the materials was found to be in the order: Colocasia esculenta mucilage > Acacia > Compound Tragacanth. The Study indicates that Colocasia esculenta mucilage may be useful as a pharmaceutical adjuvant and as a suspending agent
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