We describe a rare case of hypertension and bilateral pleural effusion simultaneously in twenty-two years old otherwise healthy young female in March 2017. The patient presented with an allergic reaction to an insect sting. Hence, she developed a generalized rash and shortness of breathing where she received a methylprednisolone 80 mg intravenously every 8 hourly for five days where she was discharged home. However, the patient readmitted within 24 hours with non-resolving shortness of breathing, dry cough, hypertension and bilateral pleural effusions more significant on the right side are confirmed clinically and radiologically. Five days after methylprednisolone was discontinued, patient became normotensive and chest x-rays was normal. These manifestations that include symptoms, signs and radiological images and their resolutions are given a name of a syndrome called “Yahya Al –Fifi’s syndrome