Needle stick injuries are wounds caused by needles that accidently harm the skin. These wounds are harmful for individuals who work with needles and other sharp equipments. These wounds can happen whenever individuals utilize, or discard needles. Needle stick injury (NSIs) is genuine reason behind blood borne infection transmitted among wellbeing mind personals. Administering infusion, pulling back blood, recapping needles, arranging needles, treatment of junk and dirty materials and exchanging blood or body liquid from syringe to example compartments are typical activities related with sharp injuries. The objective of this study is to assess knowledge and practice of needle stick injury among nurses. The significance of the study is that this study is beneficial for all nurses, undergraduate students and other health organization. In conclusion, the awareness of the nurses regarding needle stick injury and its preventive measure on their practical training was poor. A survey was finished by 253 nurses. In this review, needle stick harm was characterized by percutaneous harm brought about by empty borne needles, suturing needles, surgical tool and blades. In this review 77.1% nurses have great learning 20.2% have poor information and 2.8% have no information about empty borne needles and the fundamental driver of percutaneous wounds with empty bore needles were recapping). The greater part of wounds happened after utilize what's more, before disposal of the objects. . All in all, the familiarity with the nurses to needle stick harm and preventive measure and application on their functional preparing was poor. It would be suggest that the wellbeing training program for needle stick damage and preventive measure should be introduced to all the nurses and encourage them to apply during their daily practice