A disaster is an incident that can causes massive damage and destruption. Disasters are common worldwide event now a days. Nurses role are very important in disaster management and its recovery. The purpose of this study was to assess the nurses' knowledge and practices Regarding disaster management and emergency preparedness. The objectives of this study was To assess the knowledge and determined the current practices of nurses in the emergency department and to identify the hospital specific plans regarding the disasters management. The Quantitative cross sectional study design was used in this study. semi stracture Questionnaire was used to collect the data. The questionnaires were administered by using convenient sampling. Data were statistically analyzed by descriptive criteria such as number, percentage, mean, median and standard deviation on SPSS version 21 and inferential statistics. Chi square test was used to check the relationship between the variable. The results of this study showed that Participant nurses have a good knowledge on disaster and its management. Overall good knowledge was 65.4%. However the practices were poor and overall poor practices were 83.3% so therefore it should be still need to do work on it. The conclusion of this study include that nurses knowledge about the disasters were good but practices were poor in the hospital setting. There is need to work on the practice and knowledge as well in these two hospital. The study revealed that hospitals currently have deficiencies in practices and management. Further, follow up research are necessary for maximizing nursing education and nursing quality.