It is common in the intensive care unit to have many syringe pumps connected to a stopcock manifold and then attached to the port of a central line. The treatment of such critical patients also involves the alteration of flow rates of these syringe pumps. There are varied practices with respect to how the syringe pumps are placed when connected to the central line. Three syringe pumps containing inert fluid with a prefixed amount of different measurable electrolytes were connected to a central line via stopcock manifold .These pumps were commenced at a predetermined flow rate .At the end of prefixed intervals the samples were analysed to assess the quantity of electrolytes in the fluid delivered at the end of a central line. Alteration in flow rates and their subsequent end effect was studied. Further an infusion pump was connected to the distal end of the manifold and the fluid mechanics with various permutations of flow rate were studied. As per the results of our study, when a carrier infusion pump was connected in series to multiple syringe pumps connected to the manifold , the initial 5 minutes showed a significant dilutional effect for the contents of the proximal infusion pump (closest to the central line port)when alteration were made to the other pumps. This laboratory experiment does seem to suggest that there seems to be a significant dilutional effect with the use of carrier infusion in series as compared to when the carrier infusion is not used when drug alterations are done . This study further lays an impetus to study the above experiment in vivo in order to ascertain whether this has biological relevance.