The oral care is essential component of nursing job and it have great impact on patient’s safety and comfort during hospitalization. It prevent from hospital acquired infections. Mortality and morbidity rates are increased due to poor oral hygiene .Nurses are accountable for oral care but oral care is neglected in hospitals due to poor knowledge, attitude and practices. The aim of study was to determine nurse’s knowledge, attitude and practices towards oral care. Quantitative, descriptive cross sectional study design was used to achieve the aim of the study. The study was conducted in services hospital Lahore, Pakistan. The study population was registered nurses working in services hospital Lahore, Pakistan. Sample size was be 222. Data was collected by convenience sampling. Tools: for data collection: I: Demographic characteristics, 2: Mouth hygiene knowledge sheet, 3: Attitudes regarding oral care, Part 4: Practice towards oral care. The data was analyzed using (SPSS) mainly descriptive statistics methods percentage distribution. Chi square to test the associations between variables. Results: the mean and St. D of the age of participants was 1.77+ 0.800 with maximum experience of 1 - 5years 38.7% (n= 86). Educational level of participants was diploma in Nursing 69.8% (n= 115). The nurses had knowledge had fair knowledge >50% and Attitude level was negative < 60% and Practice level was poor < 60%.Majority of nurses do not perform oral care and give it less priority Oral hygiene care is often missed and neglected care. There is need to improve the nurse’s knowledge and practice by training sessions, seminar and workshops. Nurses are in great need to improve the skill and competency to improve patient quality care