Marine algae are in exhaustible sources of chemical compounds contain bioactive compounds that plays an important role against various diseases against the aging process because they protect cells from oxidation. The present study is aimed to analyze the phenol and flavonoids content of the marine red alga Tolypiocladia glomerulata and their potential of free radical scavenging properties. The free radical scavenging capacity of the red alga was analyzed by inhibiting the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS). The maximum percentage of inhibition (61.13 ± 0.02% for DPPH and 50.35 ± 0.00 for ABTS) was observed at the concentration of 900 μg/mL. The free radicals scavenging ability of extracts followed close dependent trend. The results indicate that the red alga T. glomerulata have good free radical scavenging capacity with ABTS and DPPH and it could be used as a potential candidate for natural antioxidants