Studies on gender disparities of traditional cardiovascular risks such as anthropometric factors are limited in black Africans. We aimed to examine the relationship between anthropometric parameters and blood pressure (BP) and possible gender differences in hypertensive adult Nigerians. A cross sectional study was carried out involving 261 adult hypertensive patients recruited consecutively at the medical out-patient clinic of Niger Delta University Teaching Hospital. They comprised 118 males and 143 females aged 26years to 94years. Their BP and anthropometric measurements were assessed using standard protocols. More than 70% of subjects were either overweight or obese. Females had significantly higher WC, WHtR and BMI than males. For females, BP had a significant positive correlation with anthropometric measures and a regression analysis showed BMI in females was the most important anthropometric index in predicting systolic BP (SBP) and diastolic BP (DBP). For males, none of the anthropometric measures correlated with SBP or DBP. Female hypertensives were significantly more obese than males. Indices of adiposity in females had a direct relationship with BP but not so in males. Further studies are needed to assess gender disparities in cardiovascular risk factors.