Cryptococcosis is a potentially fatal fungal disease. The prevalence of cryptococcosis has been increasing for many reasons, including the increase in incidence of AIDS and the expanded use of immunosuppressive drugs. Cryptococcal meningitis is a threatening disease and visual loss is reported as a rare manifestation due persistent papilledema and optic nerve involvement. We report a case of an immunocompetent young male who presented with cryptococcal meninigitis, left lateral rectus palsy and papilledema. Inspite of appropriate medical therapy with amphotericin and flucytosine, his papilledema persisted and developed decreased vision.