Alcohol consumption has been an accepted social practice since time immemorial. Alcohol, a drug, is consumed at some time by up to 80% of the population. The consumption of more than two standard drinks per day increases the risk for health problem in many organ systems. The objectives of the present study was to find out the alcohol usage profile among the adult alcohol users from Chidambaram town and the association between drinks per episode, episode per year, duration of diabetes mellitus and liver enzymes. The study was a descriptive cross-sectional study was carried out in the field practice area of Urban Health centre (UHC) under Community Medicine, Rajah Muthiah Medical College and Hospital (RMMCH), Chidambaram, Annamalai University between October 2015 and July 2016.Majority (78.43%) of the study subjects AST enzyme value of ≤40 units/ litre that shows within normal limit. Majority (83.00%) of the study subjects ALT enzyme value of ≤40 units/ litre and also in normal limit. Majority (88.88%) of the study subjects GGT enzyme value of ≤60 units/litre. Duration of being alcoholic, number of episodes per year and drinks per episode were influencing the liver enzyme values significantly. Candidates having increased liver enzymes also are potential candidates to have hepatic damage. Hence by decreasing the alcohol quantity and also interventions that aid in stopping alcohol would help in preventing hepatic damage